I needed to disable self sign-ups because I’ve been getting too many spam-type accounts. Thanks.
Grant's "RBP as Antibodies" blog post
Hey, great blog post! Can we talk about it here?
I lolled when Grant said: "Of course, it always comes down to needing a “drug” to “block” something. Using a non-drug based therapy is completely unthinkable to these folks. "
Sometimes it makes me feel frustrated to think that something that starts out as such a common thing in the vegetable world could cause so many problems. What are we aliens or something?
I digressed into a corn tangent here. To try and fix this, I moved the bulk of the text to a thread titled "Walking Corn". I left a few tidbits since I can't delete the posts entirely.
Eggs laid on rice-based diet, vs eggs laid on corn-based diet:
"We North Americans look like corn chips with legs,” says one of the researchers who conducts such tests." (from a Michael Pollan article) Roundup (which impairs our vit A detox) began to be used in the 1970's... to make using roundup on corn fields easier, roundup ready corn was developed in the 90's.
Thanks lil chick, I wanted to leave a comment to Grant on this blog post but the formatting on the comment field is so messed up that its not possible to post a comment no matter what browser I use. I will post the comment here:
"Hi Grant,
Interesting post, I'd agree that it looks more like the role of RBP is to "shield" the body from RA.
Just a point about some of these techniques you mention like ELISA, Western blot and Immunofluorescence. They are all based on the same principle, but the idea is actually not that what they detect are antibodies, rather all these techniques use antibodies that have been generated to specifically bind a certain protein, to detect this protein, so these techniques are widely used to detect and measure proteins of all kinds, including hormones and neurotransmitters, etc, not just antibodies.
Also, I’m curious, what are your thoughts on how the various “receptors” for retinoids like RAR and RXR fit into this? If retinoids are not actually used as signalling molecules, what is the purpose of these receptors?"
Also, I’m curious, what are your thoughts on how the various “receptors” for retinoids like RAR and RXR fit into this? If retinoids are not actually used as signalling molecules, what is the purpose of these receptors?"
You may find this post of Garrett Smiths interesting. https://www.facebook.com/DoctorAsTeacher/posts/10217830604690666
He is saying that Retinol is not the natural binding molecule for RXR and that it's name (RXR) is not helpful because it propagates the idea that Retinol is necessary.
Wow, Grant, that RBP as Antibody post made my day!! Now we have another unique conceptual tool to apply to deciphering many of these research studies. I'll let you know how it plays with the Alzheimer's fundraisers I have been interacting with lately.
I've always had a problem with the "receptor" thing, jumping from studies to Wikipedia and back to sort out what they actually do. One thing that came to mind while reading your latest was that perhaps the receptors are just anchor-points, where the toxin is held steady, while the insulative protein is wrapped-around it by whatever is doing the crochet-work. It would make some sense of why these toxic molecules are always at the "scene of the crime", like guilty crooks milling about, being detained and interviewed, unidentified as such (by researchers) in the confusion of inflammatory events. And it's not like the threatened cells are simply throwing RBP "nets" willy-nilly, I wouldn't suppose. It has to be a highly-structured process where the "perp" is handled carefully, one molecule at a time as you point out, like when a spider is wrapping its prey, and in this case a dangerous one. Just rambling here, but I've spent a week trying to decode the RA - Microglia thing and there's only a few papers concerning it, but with your new insight, it will be worth plowing through them again to look for clues that might add to your evidential stack. There's a Goldilocks Game they play in these studies, the too-much or too-little game, as if we're little leaves buffeted by unruly winds, too fragile to make our own way without expert guidance and just the right "formula", whatever that might entail (which they never even attempt to elucidate).