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How does A leave the body?
How exactly does A leave the body?
- Sadie
Quote from Guest on January 15, 2019, 7:58 pmHow exactly does A leave the body?
- Sadie
I feel that eating foods (or spices such as garlic...think about French cuisine and their butter and garlic in almost everything which I don't think it's a coincidence) with antibiotic properties along with vitamin A and carotene rich foods helps with minimizing absorption. That can explain why in some aspects saturated fats are helpful . All saturated fats have some antiseptic properties and this can explain why butter may be okay despite containing vitamin A. I think that onions even when cooked retain some antibiotic properties too. For example spinach can be edible if you prepare it with tons of cream and butter and add garlic as a spice.
Retinol (fat-soluble) is conjugated with glucuronic acid and then further metabolized to retinal and retinoic acid. Retinoic acid is excreted in feces via biliary elimination. Retinal, retinoic acid, and other water-soluble metabolites excreted in urine and feces.
Ethanol, morphine, paracetamol (acetaminophen), cyclooxygenase inhibitors (NSAIDs), endogenous steroids, and certain benzodiazepines are all capable of contributing to GCA depletion, with ethanol and acetaminophen being the most commonly implicated substances involved in cases of accidental overdoses which have been positively attributed to glucuronic acid depletion.
Probably why smoking helps decrease vitamin A:
Excessive quantities of GCA can also be hazardous to health, tobacco smoke, most barbiturates, and some carbamates are known to actually stimulate GCA production.
Glucuronic acid is a precursor of ascorbic acid (vitamin C, formerly called as L-hexuronic acid). Ascorbate can be biosynthesized by higher plants, algae, yeast and most animals. This ability is lacking in some mammals (including humans and guinea pigs) and also in insects, invertebrates and most fishes. These species require external ascorbate supply, because they lack the biosynthetic enzyme L-gulonolactone oxidase.
I've been thinking about that too. Dr. Smith says that it will get excreted the normal ways - poo and pee and sweat. I've have been low vA for almost 4 months and haven't had many signs of the vA leaving - sometimes lose stools. Finally the last 2 mornings I've had diarrhea which I think is a great sign. I finally slept 7 hours in a row last night. For the past 2 weeks or more I could only sleep 3 to 5 hours at a time so I think my body finally dumped some vitamin A. I don't know why it took so long if that is want indeed happened. I didn't feel sick otherwise so I believe the diarrhea was to get rid of the A.
This makes me wonder if that is why my white clothing tends to get dingy stains in the areas where I sweat the most.
Quote from Guest on January 16, 2019, 8:08 amI've been thinking about that too. Dr. Smith says that it will get excreted the normal ways - poo and pee and sweat. I've have been low vA for almost 4 months and haven't had many signs of the vA leaving - sometimes lose stools. Finally the last 2 mornings I've had diarrhea which I think is a great sign. I finally slept 7 hours in a row last night. For the past 2 weeks or more I could only sleep 3 to 5 hours at a time so I think my body finally dumped some vitamin A. I don't know why it took so long if that is want indeed happened. I didn't feel sick otherwise so I believe the diarrhea was to get rid of the A.
Has your health improved in this period?
Not really. I would say that overall I feel worse than I did a year ago but I am convinced that it is vitamin A that is causing my problems so I will stick with the diet for as long as it takes to heal.
If you're not feeling better in any significant way after a few months on the diet, I would advise you to correct the course.
I would look for ways to support your recovery, or try to identify some other sensitivities/deficiencies your body could have. I myself can't do much beef. Even on a low A diet, beef seems to wreck havoc in my gut and constipate me.
I don't believe we have to suffer through intense detox. Sure, there will be times when you feel sicker, but it should be occasional and for a few days. (That's my point of view, I might be wrong, but Grant did see some improvements from the get go)
I have changed the low vA foods I eat and the amounts of them. Also, one thing I didn't really do for the first 2 to 3 months is eat mostly organic, so that may have been something to hold my healing back. I think there is usually outliers and unfortunately I think I am one of those as far as how long it will take me to improve, though maybe there are many others who are like me and they just aren't heard from - it doesn't seem like there is a big enough sample size to know how long it takes to heal. Grant made a comment somewhere here than he knew of others that didn't improve in the first few months and so they gave up.
I think it very difficult for Vitamin A to leave the body. Its half life is 200-300, and the body also recycles Vitamin A via bile. Additionally, the amount of Vitamin A consumed serves as a signal for body on how to regulate/regenerate skin, cells, etc. Depleting yourself of Vitamin A is very difficult to do even if you go on a low Vitamin A diet for a few months.