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Another possible effect of winter months on vitamin A toxicity
It's quite cold right now in Quebec (Eastern Canada). At the beginning of the week, I was wearing a light jacket. I was feeling a bit cold outside so I changed to my winter jacket. Since changing my jacket, I have noticed a lowering of my energy levels and cognition ability. My insomnia has also worsened.
I have noticed that my coat is too hot, I get sweaty during transit which include getting on the metro and the bus. Could increased temperature near the skin create adverse effects from retinoic acid?
My theory stems from the fact that the molecule is quite heat sensitive and I think I remember reading that it could be released from fat cells during sun exposure?
Since I have also started lowering vitamin A at about the same time, it could also be this. I will have to switch jackets again to see if I can reproduce the effect.
Grant mentions in his books that warming the skin could allow the retinol to escape from the sebaceous glands, allowing it to be converted into Retinoic Acid. It's probably this.