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Asprin for treatment of Vitamin A toxicity
Quote from r on July 5, 2024, 12:25 pmThe effect of retinol and acetylsalicylic acid on the release of lysosomal enzymes from rat retina in vitro
THIS study was designed to provide an indirect assessment of the possible role of prostaglandins in retinoid intoxication. If the symptoms of retinoid toxicity are mediated by prostaglandins, an inhibitor of prostaglandin synthesis should ameliorate the symptoms of sublethal intoxication and perhaps even increase the lifespan of mice treated with lethal doses of retinoids. The observations reported here indicate that aspirin can antagonise the toxic effects of retinoic acid.
https://sci-hub.se/https://www.nature.com/articles/269511a0
are 5-ASA similar to aspirin ? if so , it explains why mesalamine works for IBD/UC patients
The effect of retinol and acetylsalicylic acid on the release of lysosomal enzymes from rat retina in vitro
THIS study was designed to provide an indirect assessment of the possible role of prostaglandins in retinoid intoxication. If the symptoms of retinoid toxicity are mediated by prostaglandins, an inhibitor of prostaglandin synthesis should ameliorate the symptoms of sublethal intoxication and perhaps even increase the lifespan of mice treated with lethal doses of retinoids. The observations reported here indicate that aspirin can antagonise the toxic effects of retinoic acid.
https://sci-hub.se/https://www.nature.com/articles/269511a0
are 5-ASA similar to aspirin ? if so , it explains why mesalamine works for IBD/UC patients
Quote from Janelle525 on July 10, 2024, 6:31 amQuote from r on July 9, 2024, 11:48 pmhowever will damage kidneys in long run
I agree my husband was on aspirin for many yrs to help his obstructive sleep apnea and his kidney function is worse than mine. He also has high blood pressure.
Quote from r on July 9, 2024, 11:48 pmhowever will damage kidneys in long run
I agree my husband was on aspirin for many yrs to help his obstructive sleep apnea and his kidney function is worse than mine. He also has high blood pressure.