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Asprin for treatment of Vitamin A toxicity

The effect of retinol and acetylsalicylic acid on the release of lysosomal enzymes from rat retina in vitro

THIS study was designed to provide an indirect assessment of the possible role of prostaglandins in retinoid intoxication. If the symptoms of retinoid toxicity are mediated by prostaglandins, an inhibitor of prostaglandin synthesis should ameliorate the symptoms of sublethal intoxication and perhaps even increase the lifespan of mice treated with lethal doses of retinoids. The observations reported here indicate that aspirin can antagonise the toxic effects of retinoic acid.

https://sci-hub.se/https://www.nature.com/articles/269511a0

are 5-ASA similar to aspirin ? if so , it explains why mesalamine works for IBD/UC  patients 

however will damage kidneys in long run 

Quote from r on July 9, 2024, 11:48 pm

however will damage kidneys in long run 

I agree my husband was on aspirin for many yrs to help his obstructive sleep apnea and his kidney function is worse than mine. He also has high blood pressure.

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