Quote from Ourania on July 11, 2025, 10:34 am

We have been using calcium-D-Glucarate 500 mg once or twice day for the last two weeks.

Very good results : teeth much smoother, bits of tartar falling off! I don’t think this is due to the calcium in it as it is supposed to be a very small quantity. In the morning we don’t have morning stiffness, less and less. I think it mops up stuff which is supposed to go out in lymph but gets reabsorbed again and again.

Not sure how long the honeymoon period lasts, but it is a huge plus.

@lil chick

Quote from Ourania on July 12, 2025, 2:15 am

Thank you @itsme. I suffered from this all my life as well as vA intolerance (not lactose intolerance but a deep hatred for all vA foods). I escaped the consequence as long as I was on progesterone.

I think there is a link there. Interestingly it also works on my husband.

Quote from Tanveen on July 12, 2025, 3:24 am

There seems to be a link between vitamin A and estrogen and cell proliferation.  The first article also mentions thiamine (b1) and riboflavin (b2) relates to estradiol inactivation of liver slices  

https://academic.oup.com/nutritionreviews/article-abstract/3/10/308/1908359?redirectedFrom=PDF

there seems to be some research around vitamin a metabolising estrogen (estradiol) to an inactive form (estrone) 

https://joe.bioscientifica.com/view/journals/joe/148/2/joe_148_2_010.xml

does carotene suppress the normal estrous cycle (they say no but I read with the framework of vitamin a toxicity in mind) 

https://academic.oup.com/endo/article-abstract/29/1/164/2773391

https://www.functionalps.com/blog/2012/04/23/vitamin-a-anti-cancer-and-anti-estrogen/

link to thyroid and progesterone (substitute deficiency with toxicity).  So high vitamin a can lead to high amounts of iron stored in the liver, negatively impacting thyroid hormone conversion and estrogen detox and the hundreds of other essential functions the liver performs  

https://hormonehealingrd.com/blog/vitamin-a/

https://www.tandfonline.com/doi/pdf/10.1080/01635589609514452

Link doesn’t work but the blurb says calcium-D-glucarate lowers estradiol 

https://www.spectracell.com/blog/posts/bid-87780-nutrient-correlation-wheel-on-estrogen

 

 

 

 

 

 

 

Quote from Tanveen on July 12, 2025, 5:23 am

I have been eating a lot of apples for a few days now (as I thought may be the lamb, rice and beans was leading to too much iron and I am getting yellower, skin is red if I itch and apples seem to settle my stomach) and they seem to help (I didn’t realise they contain calcium d glutamate). I am wondering if I do this for a while whether I will then be able to eat the low vitamin a diet 3 times a day again (I’ve been having apples in the day and the low vitamin a diet in the evening). 

Quote from Tanveen on July 12, 2025, 5:31 am

Or may be it is helping with Gilbert’s syndrome (I have high billirubin levels and Gilbert’s Syndrome) 

https://gilbertssyndrome.org.uk/calcium-d-glucarate-helps-fight-gilberts-syndrome-symptoms/

Quote from Shannon on July 15, 2025, 6:00 pm

I have issues with Calcium D Glucarate.

It forces the glucoronidation of metabolites to "stick" and not get de-tagged for re-absorption.

I have a theory that this can cause an uptick of liver metabolism toxic intermediates, but...I'm a bit of a canary in a coalmine here.

If one can handle the CDG, I would think it would be beneficial. I don't know why one would want to reabsorb what was tagged for removal.

Quote from Ourania on July 16, 2025, 2:57 am

Thank you @shannon for your input. At the moment (about three weeks in) we feel well. Less and less rigidity after waking up. As usual it is  much more visible on my husband : the white of his eyes has turned pearly white and the irises very very blue.