I needed to disable self sign-ups because I’ve been getting too many spam-type accounts. Thanks.
idiopathic intracranial hypertension... Amines..broken-down proteins.
"What increases my risk for IIH?
- Being female
- Obesity
- Too much vitamin A or tyramine
- Certain medicines, such as steroids, tetracycline, or birth control pills
- Medical conditions, such as hypertension or sleep apnea"
edited title to add second phrase
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1125522/
"
Not so benign intracranial hypertension
That a common antibiotic, doxycycline, used to treat malaria, acne, and other infections could cause increased intracranial pressure is not a recent revelation.1 Other tetracyclic antibiotics such as minocycline and tetracycline have caused intracranial hypertension.
Benign intracranial hypertension is a syndrome of signs and symptoms of increased intracranial pressure without causative lesions on images obtained by magnetic resonance imaging or computed tomography.2The disorder is controversial from its name to its putative pathophysiology, but it should be considered when anyone taking doxycycline begins to complain of a new headache.
The first controversy surrounding the disorder is the name—benign intracranial hypertension. For over 100 years the condition has been known as pseudotumour cerebri or benign intracranial hypertension.3 Corbett and Thompson, following the lead of Buchheit, made a plea to replace “benign” with “idiopathic,”4 to set apart the idiopathic form of increased intracranial pressure from symptomatic forms, and to dispel the notion that the condition is totally benign.
"
more at link
From Wikipedia:
"Research reveals a possible link between migraines and elevated levels of tyramine. A 2007 review published in Neurological Sciences[35] presented data showing migraine and cluster diseases are characterized by an increase of circulating neurotransmitters and neuromodulators (including tyramine, octopamine, and synephrine) in the hypothalamus, amygdala, and dopaminergic system. People with migraine are over-represented among those with inadequate natural monoamine oxidase, resulting in similar problems to individuals taking MAO inhibitors. Many migraine attack triggers are high in tyramine.[36]"
"Specific foods containing considerable amounts of tyramine include:[6][7][8]
- strong or aged cheeses: cheddar, Swiss, Parmesan; Stilton, Gorgonzola or blue cheeses; Camembert, feta, Muenster.
- meats that are cured, smoked, or processed, such as salami, pepperoni, dry sausages, hot dogs, bologna, bacon, corned beef, pickled or smoked fish, caviar, aged chicken livers, soups or gravies made from meat extract.
- pickled or fermented foods: sauerkraut, kimchi, tofu (especially stinky tofu), pickles, miso soup, bean curd, tempeh, sourdough breads
- condiments: soy, shrimp, fish, miso, teriyaki, and bouillon-based sauces.
- drinks: beer (especially tap or home-brewed), vermouth, red wine, sherry, liqueurs.
- beans, vegetables, and fruits: fermented or pickled vegetables, overripe fruits.
- chocolate[9"
Quote from lil chick on June 22, 2023, 5:20 pm"What increases my risk for IIH?
- Being female
- Obesity
- Too much vitamin A or tyramine
- Certain medicines, such as steroids, tetracycline, or birth control pills
- Medical conditions, such as hypertension or sleep apnea"
The big question would be which types of Vitamin A and/or their metabolites.
I do experience intracranial blood pressure abnormalities along with brain buzziness. And, occasionally, headaches.
But, I imagine it to be a wave of retinyl compounds being metabolized. However, it could also be a release of other carotenoids that I used to consume in high volumes (astaxanthin in supplements / Pacific salmon, lutein from so many plants, etc.)
An "antidote" might be nice (while detoxing, that is). However, it generally is getting better unless I come across too many aldehydes (like a serving of alcohol would generate), or increase NAD+ too much. (fasting, Niacin, etc.)
Click to access 2015%20Migraine.pdf
"Migraine is associated with an overload of Tyramine from food. The liver is only able to process this Tyramine at a rate unique to the individual."
An explanation of why this often affects women in a cyclical fashion (however, I think the description is confusing, I would guess this is an explanation of PMS, and that the days that are worse are the 3 days leading up to menses and during menstruation (so, yes, ten days in all), and the good days are during the first phase of buildup of fertility and preparation of the ova, and the short wait to see if anything implanted):
"In time you will be able to refine the limit. Women will find they have 2 limits, one in the 10 pre- menstrual days and one for the rest of the time. This is due to the liver acting to remove the female hormones at the latter end of each cycle and this action reduces the clearance of Tyramine, hence you will maintain a higher Tyramine level and be more prone to a migraine event."
"Other experiential “triggers” are
Alcohol and caffeine
Darrk green veg, especially cucumber skins, broad bean pods.
Citrus fruit, usually orange, lemon, lime less likely apple and not grapefruit Figs, dried or green
Mushrooms
Stock cubes or gravy brownings
Cheese – especially strong hard or aged cheeses"
Basalmic vinegar really makes me sick. But it's not a migraine kind of sick.
My migraines can be triggered by physical nerve pressure when the sinuses are swollen. I probably subconsciously avoid eating too much of foods that would also trigger.