I needed to disable self sign-ups because I’ve been getting too many spam-type accounts. Thanks.
Immune system vs. gut bacteria: How vitamin A 'keeps the peace'
https://www.medicalnewstoday.com/articles/324066.php
Key quotes:
moderate levels of vitamin A in the intestine prevent the immune system from becoming overactive.
Using a mouse model of the microbiome, Vaishnava and team found that these gut bacteria regulate their hosts' immune responses by adjusting a protein that activates vitamin A in the gastrointestinal tract.
The protein is called retinol dehydrogenase 7 (Rdh7) because it transforms vitamin A to retinoic acid, which is vitamin A's active form.
Furthermore, the scientists found that Firmicutes bacteria — more specifically, bacteria that are part of the Clostridia family — lower the expression of Rdh7. Clostridia bacteria also cause the liver to store an increased amount of vitamin A, the scientists found.
"This research could be critical in determining therapies in the case of autoimmune diseases, such as Crohn's disease or other inflammatory bowel diseases, as well as vitamin A deficiency."
It seems like scientist never challenge the status quo. They assume that vitamin A is a vitamin and build a case from there. I am interested if someone else can draw conclusions out of this maybe Grant can share his opinion?