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Liver detox and vitamin A
Would you recommend doing a liver detox (like coffee enema, herbs, flushes) in order to speed up vitamin A detox?
Is bile flow important for vitamin A detox? When someone has congested liver, will the diet itself help?
Thanks.
That’s an excellent question. Thanks for asking.
I have no first-hand knowledge with it. I did not experiment with a liver detox. But, it sure makes sense that it could be helpful. However, I know nothing about the efficacy of a liver detox.
RE: Bile flow – yes, I believe it is hugely important in detoxing. Unfortunately, most of the vitamin A contained in bile is reabsorbed within the small intestine. So, it is a bit of a closed loop cycle in this regard. Increased bile flow could somewhat offset that reabsorption. It is also why I was speculating that taking activated charcoal at the right time of day might help capture some of that vitamin A content from the bile while in the intestine and pass it out with the waste.
There’s another person who was experimenting with Orlistat to accomplish this same goal.
Kambo is probably worth mentioning here. It's the venom of a south american tree frog that when applied to superficial burns made in the skin, induces a huge amount of vommiting. It's said to be a panacea, it's not unusual for people to vomit up so much bile from the liver that it is orange and darkly coloured.
It can really flaw you for a day, but after that there is a huge improvement in things like fatigue and depression for about a week.
I've heard stories of people restoring vision to 20/20 with kambo, might be worth trying/looking into (it sounds worse then it is 😉 )
I found lean beef to be very helpful. I think the protein helps use up the excess Vitamin A, and the additional zinc helps take care of the retinol. To get more taurine, eat the beef raw(tartare, carpaccio). Taurine is typically cooked out, especially if the beef is well done. Drinking coffee helps stimulate bile. Unsaturated fats and vinegar also stimulate bile. Keep plenty of low/0 vitamin A food around so you don't go hungry. Get plenty of rest and try not to do stressful activities in the evenings. Stretching and light cardio in the morning should help use up Vitamin A as well. Get a massage. Go to a sauna. Anything that increases circulation and perspiration should help get detox moving along. No need to go to extremes.
Quote from ggenereux on November 20, 2018, 8:28 amThat’s an excellent question. Thanks for asking.
I have no first-hand knowledge with it. I did not experiment with a liver detox. But, it sure makes sense that it could be helpful. However, I know nothing about the efficacy of a liver detox.
RE: Bile flow – yes, I believe it is hugely important in detoxing. Unfortunately, most of the vitamin A contained in bile is reabsorbed within the small intestine. So, it is a bit of a closed loop cycle in this regard. Increased bile flow could somewhat offset that reabsorption. It is also why I was speculating that taking activated charcoal at the right time of day might help capture some of that vitamin A content from the bile while in the intestine and pass it out with the waste.
There’s another person who was experimenting with Orlistat to accomplish this same goal.
I came across this blog post today http://paleozonenutrition.com/2019/04/21/ldl-cholesterol-lowered-dramatically-with-psyllium-metamucil-supplement-with-each-meal/
In the section on proposed mechanisms in humans it suggests that psyllium lowers cholesterol because it increases bile acid excretion. Could this be useful as a way of facilitating VA excretion?
Has anyone here tried D-Glucarate or Milk Thistle supplements during their detox?
Quote from Rusty Packer on August 20, 2019, 7:07 pmHas anyone here tried D-Glucarate or Milk Thistle supplements during their detox?
I took Calcium-d-glucarate but stopped after Dr. Smith advised me to. He suggested getting natural forms of glucaric acid, such as apples and cauliflower.
One supplement that I might start again soon, is something called TUDCA. I have a feeling that it's a good supplement to cycle. It's clinically shown to help people that have PBC (primary biliary cirrhosis). Interestingly PBC is an autoimmune condition of the liver, and the symptoms are extremely common to hypervitaminosis A. https://www.ncbi.nlm.nih.gov/pubmed/10968936
Another interesting supplement I'm looking into is apple pectin. Apparently, it binds toxins in the bile pretty well (similar to a bile acid sequestrant like Welchol/Cholestyramine).
Furthermore, simply eating more soluble fiber more frequently can help cleanse the bile. When I was really into heavy metal detox, several people mentioned how eating a small portion of black beans (high in soluble fiber) with each meal, dramatically helped their symptoms. I'm guessing that the body prefers fiber consistently throughout the day rather than all in one shot.
Interesting tid bit from this article: https://experiencelife.com/article/fiber-why-it-matters-more-than-you-think/
"Today, though, scientists are using newer tools to better understand the various ways fiber interacts with our bodies’ basic systems. Some of this new work shows that fiber plays an essential role in a little-known (and critically important) system in our body called enterohepatic circulation. Entero is Latin for relating to the intestines, or gut; hepatic is Latin for pertaining to the liver. This system, which has the key job of clearing all fat-soluble waste from the bloodstream, governs the progression of bile — from the liver, through the small intestine, and back again.
If we don’t eat enough soluble fiber, our bile, instead of being ushered out of the body and then replaced with fresh bile produced by the liver, is repeatedly recirculated in our system. In the process, it becomes more concentrated with toxins, which, in turn, can lead to all sorts of inflammatory diseases such as gallbladder disease, intestinal inflammation, and even skin conditions like acne, eczema and psoriasis."
An interesting study about apple pectin: https://www.ncbi.nlm.nih.gov/pubmed/1309477
Plasma beta-carotene response in humans after meals supplemented with dietary pectin.
The purpose of this study was to determine the effect of pectin on plasma response to beta-carotene in humans. Using a crossover design, we evaluated the effect on plasma beta-carotene in seven subjects when 12 g citrus pectin was added to a 2092 kJ (500 kcal) controlled meal with 25 mg beta-carotene. Plasma samples were collected at 0, 8, 30, 48, and 192 h after the meals. Plasma beta-carotene was quantified with the use of HPLC. The increase in plasma beta-carotene concentration was significantly reduced by pectin at 30 and 192 h (paired t test; P less than 0.005 and less than 0.05, respectively). Mean percent increase in plasma beta-carotene concentration at 30 h after the meal with beta-carotene was reduced by more than one-half when pectin was added to the meal. These results indicate that the inhibitory effect of pectin may provide one explanation for observations of reduced plasma beta-carotene response in humans after the ingestion of carotenoid-rich foods when compared with equivalent doses of beta-carotene supplements.
Hey @empirebuilder31, thanks for the amazing info. When you were really into heavy metal detox did you take a Humic/Fulvic Mineral Complex at all? I'm wondering if this would be a good addition to a Vitamin A detox program...