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Pinetreefire`s log
Quote from puddleduck on October 18, 2019, 7:34 amYeah, it seems like a miracle I'm still alive. I'm almost a non-functional human being now though. At the time I ate a very high protein, high fat diet so maybe that was protective in a way, idk.
From what I understand, protein is protective because it supports a healthy production of thyroid hormones, which are used to make TTR (transthyretin), which carries the retinol bound in RBP (retinol binding protein). In the wrong places, it seems that RBP does damage that TTR prevents it from doing. Not sure on the details, but some studies I’ve read indicated that was the case.
Anyway, I’m sorry to hear about everything that happened to you. And I’m sorry that you are in an almost non-functional state still. That’s a pretty rough set of symptoms. But I’m glad you’re here (welcome, btw!
), and I’m sure that recovery is possible for you. I can 100% relate to noticing fluctuations during this process. Having the toenails starting to grow properly again is awesome. I get why that’s a huge deal, even though it’s not a quality of life thing, it’s proof that change can happen.
You are the first person I have met so far who has also experienced mania and psychosis. I don’t see those on the list of Hypervitaminosis A symptoms, yet I had the worst episode of those symptoms when I was eating 5,000%+DV of vitamin A, so I do feel there could be a possible connection.
Anyway, hope you are doing well today, and that you will see solid improvements.
Thanks for the welcome. I remember reading your introduction a few months ago and finding it very helpful and also comforting in a way, knowing there might be a simple explanation to all this madness.
That's interesting about the protein. I've never heard about TTR before. I was eating huge amounts of protein for a good stretch, between 200-300g a day actually. Of course a good portion of it was probably converted to glucose though, since I ate very little carbs. I remember having cloudy urine very often, which could indicate a protein overload maybe, but who knows maybe I was dumping VA...?
Regarding the psychosis; I haven't experienced a lot of it, but there was one time this spring I had a huge amount of coffee and that triggered I´d say a moderate psychosis. I was actually backpacking alone in the wild at the time, hearing voices everywhere and I thought I was going to have a heart attack if I ever saw someone. Beside that, I've also had a number of milder ones triggered by stress.
These days I still struggle, having constant pressure in my sinus area that seems to never go away. Being emotionally numb, but at the same time highly sensitive to stress. It´s a never-ending nightmare. The worst part for me is for sure the time aspect of this. It really is heavy mentally to keep going, and I feel my patience is running out.
But at least there is no war going on in my country, I'm able to get food very easily, and I have a lot of time on my hands. It´s just going to take some time, unless we find a quicker way to detox 🙂 Thanks again.
Quote from puddleduck on October 18, 2019, 7:34 amYou are the first person I have met so far who has also experienced mania and psychosis. I don’t see those on the list of Hypervitaminosis A symptoms, yet I had the worst episode of those symptoms when I was eating 5,000%+DV of vitamin A, so I do feel there could be a possible connection.
In the FB group "Accutane Long-Term Side Effects" there are many people with psychosis, suicidal thoughts, depression, anxiety.. It seems that high doses of accutane are more detrimental than VA and carotenoids from food. But I personally never had accutane, retinyl palmitate, only natural form of VA from fish oil, food and I had suicidal thoughts, depressions, anxiety, social fobia, anhedonia too. There was one elderly man who had health consequences from accutane his whole life, never married, had no children, it's terrible that one drug can destroy a person's entire life. But if you don't drastically reduce VA in your diet, the body probably never has a chance to switch to detox mode and it's just in the storage mode all the time. (the same with oxalates, heavy metals, copper... etc.)
I have always wondered how people on this low VA diet after some time feel motivated with better mood, happiness, feeling of well-being, better social interaction as if their dopamine level in the brain had increased. And I feel mentally better after copper and after vitamin D (at the beginning of the diet I tried vitamin D and sunshine) - two of the nutrients that VA blocks or depletes. (Dietary copper-deficient animals show a reduction in noradrenaline and dopamine concentrations, together with a depressed tyrosine 3-monooxygenase activity.) Vitamin D is also important for dopamine in the brain (https://vitamindwiki.com/tiki-index.php?page=Dopamine%20increased%20with%20vitamin%20D%20supplementation%20%28in%20rats%29%20April%202016).
Hi Pinetreefire - welcome aboard!! I'm still gathering studies and watching videos on ozone therapy, so I'm not quite ready to start a thread on it, but I'm thinking it is intimately involved in detoxing VA in some way, and if not that directly, then giving a substantial boost to the energetic processes in mitochondria, systemically, and impacting the damage done by RA in that way. There are many ways to get ozone into the body, some professionally administered and some home use. There's an interesting steam-sauna with ozone called Hocatt. Not sure on the relative concentration of O3 compared to intravenous or rectal insufflation, but it's out there. It can be done much cheaper at home. The videos and equipment by the PromoLife folks worth checking-out.
The professionally administered therapy I'm going to try, hopefully this week, is called Ten Pass Ozone Therapy which is an intravenous technology. Some friends and I used to get ozone occasionally when we were chelating with EDTA and some traveling doc with a O3 generator would fill a syringe and shoot it in the drip-bag port. There was always a sense of relief for me. One time it stirred up a clearing of my lungs in a good way, right while I was sitting there. An older man in the room that day was Harry Zerbo, one of the first health-food store owners in the Detroit area way back when. He had 3 or 4 of the O3 injections and walked out of there cherry-red and smiling. He said he hadn't felt so good and warm in years. I'll report back after a Ten Pass session and let you know if it gives me a boost. Dr. Robert Rowan videos are also really interesting. He's one of the old-timers doing ozone therapy. I saw one where he did a Prolotherapy shot that included ozone (Prolozone they call it) into Dr. Hyman's shoulder joint at a training conference. Dr. Hyman is well-known in the US since he's always doing PBS fund-raisers. The look on his face after the shot was amazing, once he realized he had almost total range of motion restored.