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PubMed research papers
I got a heads-up that this Gold Nanoparticle paper was posted by HeyJude back on September 21.
Grant adds some interesting comments in his reply to that.
https://ggenereux.blog/discussion/topic/gold-nanoparticles-ameliorate-ra-induced-cell-death/
Here's an interesting one. I played around with the 'Earthing/Grounding' thing ten years ago. I ran a thick, insulated copper wire from a square-foot copper-mesh pad to a grounding rod I hammered into the earth outside the bedroom window. After reading this paper, I'm tempted to get a grounding sheet for our mattress; one that has silver wire embedded and plugs into the wall-socket for the ground connection. Check out this excerpt:
The concept that the inflammatory barricade forms from collateral damage to healthy tissue surrounding an injury site is supported by Selye’s classic studies published along with his description of the granuloma or Selye pouch (Figure 10).25,30 Moreover, research in cell biology and biophysics reveals the human body is equipped with a system-wide collagenous, liquid–crystalline semiconductor network known as the living matrix,31 or in other terms, a ground regulation system32,33 or tissue tensegrity matrix system (Figure 11).34 This body-wide network can deliver mobile electrons to any part of the body and thereby routinely protect all cells, tissues, and organs from oxidative stress or in the event of injury.23,31 The living matrix includes the extracellular and connective tissue matrices as well as the cytoskeletons of all cells.31 Integrins at cell surfaces are thought to allow for semi-conduction of electrons to the cell interior, and links across the nuclear envelope enable the nuclear matrix and genetic material to be part of the circuitry.23 Our hypothesis is that this body-wide electronic circuit represents a primary antioxidant defense system. This hypothesis is the central point of this report.
The effects of grounding (earthing) on inflammation, the immune response, wound healing, and prevention and treatment of chronic inflammatory and autoimmune diseases
That was me above, forgot to log-in. Here's a really informative one on Polysaccharides with good drawings.
Beneficial Effect of Intestinal Fermentation of Natural Polysaccharides
Here's another curious item, Hydrogen Water, that is reported to counter many of the issues of concern here. It was hard to pick an excerpt, since it is such an extensive review paper, with 338 papers cited, but this bit reminded me of what Grant recently explained regarding the alteration of the protein-making process due to retinoid damage.
Quote:
Hydrogen is able to promote changes in the expression and levels of particular proteins by regulating gene expression. Of particular importance is that hydrogen can inhibit or change the expression patterns of pro-inflammatory, pro-allergic, pro-apoptotic and pro-oxidative proteins. Many, if not most, of these proteins are over-expressed in a variety of chronic and acute illnesses. How hydrogen changes the expression of particular proteins remains an important question that is currently a topic of research in several laboratories.
Quote from John Fry on February 8, 2019, 4:15 pmHere's another curious item, Hydrogen Water, that is reported to counter many of the issues of concern here. It was hard to pick an excerpt, since it is such an extensive review paper, with 338 papers cited, but this bit reminded me of what Grant recently explained regarding the alteration of the protein-making process due to retinoid damage.
Quote:
Hydrogen is able to promote changes in the expression and levels of particular proteins by regulating gene expression. Of particular importance is that hydrogen can inhibit or change the expression patterns of pro-inflammatory, pro-allergic, pro-apoptotic and pro-oxidative proteins. Many, if not most, of these proteins are over-expressed in a variety of chronic and acute illnesses. How hydrogen changes the expression of particular proteins remains an important question that is currently a topic of research in several laboratories.
Was on a forum with many users that tested hydrogen water for few months, myself included. Everyone gave up on it, for most users it will slow metabolism greatly, which will impair/slow any healing. Just my opinion, but I would not recommend it.
Quote from Orion on February 9, 2019, 6:04 amQuote from John Fry on February 8, 2019, 4:15 pmHere's another curious item, Hydrogen Water, that is reported to counter many of the issues of concern here. It was hard to pick an excerpt, since it is such an extensive review paper, with 338 papers cited, but this bit reminded me of what Grant recently explained regarding the alteration of the protein-making process due to retinoid damage.
Quote:
Hydrogen is able to promote changes in the expression and levels of particular proteins by regulating gene expression. Of particular importance is that hydrogen can inhibit or change the expression patterns of pro-inflammatory, pro-allergic, pro-apoptotic and pro-oxidative proteins. Many, if not most, of these proteins are over-expressed in a variety of chronic and acute illnesses. How hydrogen changes the expression of particular proteins remains an important question that is currently a topic of research in several laboratories.
Was on a forum with many users that tested hydrogen water for few months, myself included. Everyone gave up on it, for most users it will slow metabolism greatly, which will impair/slow any healing. Just my opinion, but I would not recommend it.
Thanks Orion, will keep that in mind. What methods were people using? I looked around at all the options and figured HTWO packaged water was the simplest, if not the cheapest experiment. Were there any particular metabolic symptoms that stood out?
https://www.cell.com/immunity/fulltext/S1074-7613(18)30566-1?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1074761318305661%3Fshowall%3Dtrue
The Short Chain Fatty Acid Butyrate Imprints and Antimicrobial Program in Macrophages.
IMMUNITY – Jan 2019 – Hot off the press
In conclusion, our results demonstrate that butyrate directs the differentiation of homeostatic macrophages that possess strong antimicrobial activity and play an important role in preventing the dissemination of bacteria beyond the intestinal barrier. Butyrate educates developing macrophages via HDAC3 inhibition by regulating their metabolic and transcriptional program. This has implications for prevention and therapy of disorders that are associated with intestinal inflammation, as well as systemic infection.
Here's another one that covers a lot of territory on the Short Chain Fatty Acids - Butyrate, Propionate and Acetate. It's a 2018 Review that covers 94 papers. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244749/
Role of Gut Microbiota-Generated Short-Chain Fatty Acids in Metabolic and Cardiovascular Health
In the Conclusion section: "With emerging effects around the importance of SCFA for the regulation of barrier function and inflammation, it is critical that we understand the relevance of these effects for disease mitigation because there are relatively inexpensive options to intervene at the population level. The role of SCFA in managing adiposity and body weight gain is well documented in animals and the emergent role of SCFA in appetite regulation and obesity in humans also presents an exciting opportunity to intervene at a population level to tackle perhaps the most pressing health issue of our time—obesity".
Quote from Guest on February 9, 2019, 10:00 amQuote from Orion on February 9, 2019, 6:04 amQuote from John Fry on February 8, 2019, 4:15 pmHere's another curious item, Hydrogen Water, that is reported to counter many of the issues of concern here. It was hard to pick an excerpt, since it is such an extensive review paper, with 338 papers cited, but this bit reminded me of what Grant recently explained regarding the alteration of the protein-making process due to retinoid damage.
Quote:
Hydrogen is able to promote changes in the expression and levels of particular proteins by regulating gene expression. Of particular importance is that hydrogen can inhibit or change the expression patterns of pro-inflammatory, pro-allergic, pro-apoptotic and pro-oxidative proteins. Many, if not most, of these proteins are over-expressed in a variety of chronic and acute illnesses. How hydrogen changes the expression of particular proteins remains an important question that is currently a topic of research in several laboratories.
Was on a forum with many users that tested hydrogen water for few months, myself included. Everyone gave up on it, for most users it will slow metabolism greatly, which will impair/slow any healing. Just my opinion, but I would not recommend it.
Thanks Orion, will keep that in mind. What methods were people using? I looked around at all the options and figured HTWO packaged water was the simplest, if not the cheapest experiment. Were there any particular metabolic symptoms that stood out?
Most of the users bought and used machines that generate H2 water, and a few were using the magnesium rods in plastic bottles method.
Mineral hairtests where showing, high Ca and Mg, hence cells overloaded with Calcium causing slow oxidation rates(blocking thyroid).