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Weaning off Zinc/B6 supplements

I am wondering if anyone has discontinued the use of certain supplements after a time on a Low A Diet. How did you know when it was time to do this? Conversely, if you still take your supplements, how do you know that it's good to keep taking them?

I am trying to figure out how to make this call without a lot of expensive bloodwork. I know I may not be able to avoid it, but I figured I'd do some thinking first!

Background: three of my kids and I have been taking Walsh protocol supplements for the past five years. Four different scenarios, similar supps (50-100mg each B6 and p-5-p, 1000mg vitamin C, 25-70 mg zinc picolinate, magnesium, plus B1 and B2 in small amounts). Three of us tested low for zinc (and positive for "pyroluria"), although with supplementation we're up the normal range. One of us had sky-high copper even after three years of heavily supplementing zinc. One of us had high zinc AND high copper but Mensah physicians said zinc was still useful to try to regulate the copper.

Obviously zinc and copper have been dysregulated, and I am finally thinking that the Vitamin A hypothesis must be at least part of the reason why. The zinc has been amazingly helpful over the past five years, but I'm very aware that we are taking very high doses, and don't want to cause damage if/when our needs (hopefully!) decrease.

I'd love to hear about anyone else's experiences with working out new/decreasing supplement regimes.

Heavy metals and especially mercury deranges transport of the minerals - zinc and copper but others too. Andrenal fatigue - copper. Many people in the chelation group have pyroluria.  I think I have serious VA toxicity but I don't need so many supplements as like when I had heavy metal toxicity. Only now I have copper deficiency but it seems that I have already saturated it and now take only low doses as needed.

One opinion from the chelation group: 

"If Pyroluria is a condition on its own that is easily treated with zinc and b6, they why do so many people with pyroluria continue to decline in health? Answer: Because it's a symptom of an underlying problem that is not being treated, and not a condition in itself. Treat the mercury and yes it will go away. e.g. My zinc now is higher than my copper, I've never been able to do that before chelation."

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