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wrong forum, dumb question, but still.
So Grant and Smith have both said that we can visually very easily tell that the liver is toxic, in the case of fatty liver syndrome, because it is yellow. And yellow is the color of vitamin-A.
I have a question that might be stupid. Is the reason that pee is yellow because we are eliminating vitamin-A.
The more yellow it is the more we are detoxing. I have no way of measuring such things but it is not the dumbest hypothesis in the world.
Again I know this is a stupid question. Does anyone know pee is yellow.
The reason I'm asking is because I noticed that whenever I'm fasting my pee is a darker yellow than normally. And it has more gravity to it.
And I'm not dehydrated.
5 sec on google https://www.healthline.com/health/bright-yellow-urine#causes
Quote from Jiří on April 16, 2020, 11:39 am5 sec on google https://www.healthline.com/health/bright-yellow-urine#causes
I'm well aware that for every question there is an official wrong answer. Plus that article didn't really answer my question
You asked "Again I know this is a stupid question. Does anyone know pee is yellow."
first sentence in the article
"Urine color generally ranges from a pale-yellow color to deep amber. This coloring is primarily caused by the pigment urochrome, also known as urobilin."
From what I can put together, in the breakdown of red blood cells, bilirubin is produced from breakdown of heme, bilirubin is bright yellow, urobilin is one the by-products in this pathway and is yellow as well. Supp'ing riboflavin makes some nice bright yellow urine, so wasted B2 might be part of this too, and I would think the glucuronidated retinoic acid in the urine would again add to the yellow color! I think bile is mostly yellow as well? lots of yellow going on here
I'm not 100% sure , but when my urine is consistently clearer, looks like I'm lower on symptoms, than when it's consistently yellow. And I noticed the riboflavin effect too.
I'm thinking that various biologic sources of yellow would have to depend on their fat makeup, since vitamin A is fat-soluble. Pee doesn't have much fat (ideally!!), so it makes sense that the yellow in urine would come from non-vitamin A sources. Liver, on the other hand, would be the idea place to sequester fat-soluble Substances along with some extra fat to keep it in...
Just my quick thoughts
Yeah, urine is for water soluble waste. Vitamin A is fat soluble. Even beta carotene is absorbed better with fat. So I think you’re going to be excreting all forms of vitamin A primarily through bowl movements (especially when you are eating soluble fibre, because it grabs onto your bile for removal—bile is where the body’s fat soluble waste is sent).
If you aren’t pooping, you aren’t really getting rid of vitamin A. So I’m not sure long fasts would makes sense when you have vitamin A toxicity, because it would probably trigger your body to put the vitamin A back into storage (even under-eating can trigger the body to store vitamin A, because you don’t have enough nutrition to run the detox pathways).
Okay, so this is TMI for frank descriptions of poo, so be warned. 💩 If you are excreting vitamin A through your bowels, it can burn or cause cramping sometimes. You might have more gas. Constipation will happen, too, especially if you don’t have enough fibre in your diet or you undereat. And if you consumed a lot of beta carotene at any point like I did, your turds will have orange/yellow pigment clouds coming off of them, like when you rinse a paintbrush in water. When I researched this, it seemed as though typically the only thing that colours poo that way would be beta carotene, but I don’t know how to test it to confirm that. Personally, the pigment thing has been happening constantly ever since I started the detox over a year ago now, even though I don’t eat anything orange/yellow whatsoever. 😝 (I ate LOADS of beta carotene in my past, it was obscene.)
@grapes You can control how clear your urine by adjusting how much water you drink (more water makes your urine clearer). So maybe you feel better when you’re more hydrated?
Hey guys, I feel bad because apparently I toldja wrong about the vitamin A not really leaving body in the urine. 😑 Sorry about that.
@jaj In another thread, you said: “This [soluble fiber] is not the only way to get rid of vA as a substantial amount leaves in urine (I’ve recently been looking into this).”
Do you have any interesting references to post on that, JAJ?
Whoops, I see @jaj already posted some stuff in the other thread, so I will just paste it here for you @diogenes and @grapes and anyone else who comes across this so they are not misinformed:
“‘Excretion
22. The excretion of vitamin A metabolites has been reported to be about 60% in urine and 40% in faeces (Gropper et al., 2005). The amount of excreted vitamin A compounds in bile increases if the level of vitamin A in liver exceeds a critical concentration, suggesting a protective mechanism (IOM, 2001). The oxidised products of vitamin A metabolism, conjugated to glucuronic acid or taurine, are excreted into the bile for further elimination in the faeces (Gropper et al., 2005). Faecal metabolites include retinoic acid glucuronide and 4-oxoretinoic acid glucuronide, which can be absorbed and returned to the liver through enterohepatic circulation. No information was found on excretion specifically in infants or children.’
“The relevant section in Gropper:
“‘Vitamin A is excreted in both the urine and feces with the relative amounts varying based on vitamin intake. Urinary excretion of vitamin A metabolites usually accounts for up to about 60% of vitamin A excretion, and fecal excretion accounts for the remaining 40%; however, with higher intakes, fecal excretion generally exceeds urinary excretion [3]. For urinary excretion, retinol and retinoic acid are typically oxidised at the beta-ionone ring and then conjugated to generate polar, water-soluble metabolites. Many of these metabolites, especially those that are short chain and acidic, are excreted by the kidneys. Small amounts of vitamin A, however, may be expired by the lungs as CO2. Oxidised products of vitamin A that contain intact chains and have been conjugated to glucuronic acid, such as retinoic acid glucuronide and 4-oxoretinoic acid glucoronide (Figure 10.10), or to taurine are generally secreted into the bile for ultimate fecal excretion.’”