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Yeah , it this problem
I'm 99% sure that most sick people have severe iron deficiency. Hepcidin levels rise with inflammation and infection. Everyone has chronic inflammation. Therefore, iron builds up in the body and isn't used. When iron isn't used, vitamin A builds up in the liver and causes problems. The solution isn't to take iron or stop taking vitamin A, but rather to regulate the inflammation caused by trauma and chronic stress. 99% of people have iron deficiency, and so vitamin A isn't used and builds up in the liver and is toxic
A diet high in iron and reducing inflammation and stress is more the solution. Every vitamin A you eat will be toxic because you can't use the iron. A carnivorous diet, just meat and dextrose, I think is the solution. Meat, iron. Dextrose to reduce inflammation and increase iron, and vitamin A begins to be used. The carnivorous diet creates more inflammation over time, and you'll only be able to eat meat. And any food with vitamin A will make you sick. Fermented goat's milk also works; iron is mobilized, and vitamin A begins to be utilized. Older people have more inflammation, more accumulated iron, more iron that you can't use.
dairy with meat, creates inflammation and iron accumulates and is not absorbed.
Why goat's milk and cow's milk don't work: The high amount of calcium in cow's milk can inhibit iron absorption in the intestine.
Can cause blood loss:
Consuming too much cow's milk can cause micro-injuries in the intestines, leading to small amounts of blood and contributing to iron deficiency anemia.
Only fermented goat's milk, yogurt, or kefir can be used. Regular milk is not.
When noting iron deficiency in these cases, are you talking about people with adequate or more than adequate iron intake but inability to access and or utilize that iron and therefore suffer from deficiency in spite of having plenty of iron?
Yes. High-calorie diets can increase levels of interleukin-6 (IL-6), a pro-inflammatory cytokine, especially when they contain high levels of added fructose or are associated with obesity, as macrophages in adipose tissue release IL-6 in response to this excess energy. An inflammatory dietary pattern, characterized by a high consumption of red meat and sweets, is also correlated with an increase in this cytokine.
Inflammation: Stress can cause inflammatory responses, which in turn activate the production of cytokines such as interleukin-6 (IL-6).
Hepcidin production: IL-6 and other inflammatory and stress stimuli (such as early life stress) increase the expression and production of hepcidin in the liver.
Reduced iron availability: Hepcidin acts on ferroportin (the only iron-exporting protein) in the intestine and macrophages, causing its degradation. This decreases:
The absorption of iron from food.
The release of iron by macrophages and other tissues.
Anemia of chronic disease: The result is a decrease in circulating iron in the blood, as it is "sequestered" within cells (intestines, liver, macrophages), even if the body is not actually iron deficient.
In summary: Stress can be a triggering factor for anemia associated with chronic diseases by activating the hepcidin-ferroportin pathway, resulting in sequestration of body iron and reduced availability of this essential mineral.
Is this why so many former and current keto and carnivore are talking about donating blood now to get their ferritin levels down?
What is ferritin? What does it do? What does it indicate? Why would anyone want to get their levels down?
Also of note, when I started low vA I came off 12 years of keto. Symptoms indicated lack of bifido. Way too much lacto. Been slowly bringing back bifido since. Was told that keto and carnivore starves bifido out. Complete lack of bifido is routine for everyone keto carnivore.
Quote from Joe2 on September 15, 2025, 5:30 pmIs this why so many former and current keto and carnivore are talking about donating blood now to get their ferritin levels down?
What is ferritin? What does it do? What does it indicate? Why would anyone want to get their levels down?
Also of note, when I started low vA I came off 12 years of keto. Symptoms indicated lack of bifido. Way too much lacto. Been slowly bringing back bifido since. Was told that keto and carnivore starves bifido out. Complete lack of bifido is routine for everyone keto carnivore.
If too much meat causes inflammation, iron is not absorbed and is stored. Iron moves through the body bound to the protein transferrin, which transports it through the blood to distribute it to tissues, especially to the bone marrow for the production of hemoglobin in red blood cells. Hepcidin, a hormone produced in the liver, regulates the amount of iron released and absorbed, controlling its balance in the body.
The Role of Transferrin
Transferrin is the main iron transport protein in the blood.
It binds to iron and transports it to the places where it is needed, such as the bone marrow to form red blood cells.
The liver, where it is primarily synthesized, is responsible for transferrin production.
The Regulation of Hepcidin
Hepcidin is a hormone produced in the liver that controls the absorption and movement of iron.
It works by degrading ferroportin, a protein that transports iron out of cells, thus regulating the body's iron stores.
Other factors and components
Ceruloplasmin
: Helps convert iron into a form that can be absorbed by transferrin.
Copper
: Necessary to ensure iron moves properly to its destination in the body.
Vitamin C (ascorbic acid)
: Improves the absorption of non-heme iron (from plant sources) when consumed at the same meal.
Foods with phytates and tannins
: Compounds present in whole grains, tea, and coffee, which can hinder iron absorption if consumed together.
¿Es por esto que tantos antiguos y actuales seguidores de la dieta cetogénica y carnívora están hablando de donar sangre ahora para reducir sus niveles de ferritina?
¿Qué es la ferritina? ¿Qué función tiene? ¿Qué indica? ¿Por qué alguien querría reducir sus niveles?
Cabe destacar que, cuando empecé con baja acidez vascular (VA), abandoné 12 años de dieta cetogénica. Los síntomas indicaban falta de bífido. Demasiada lactosa. Desde entonces, he ido recuperando poco a poco el bífido. Me dijeron que la dieta cetogénica y la carnívora eliminan el bífido por inanición. La falta total de bífido es habitual en todas las dietas cetogénicas y carnívoras.
Sí, ahora estoy empezando a ver que mis bífidos, que ya estaban en apuros, probablemente murieron a causa de mi dieta carnívora (con pocas fibras añadidas... quién sabe qué habría pasado si no hubiera hecho eso).
Era/es una espiral descendente que se perpetúa. Los problemas que tenía, que me llevaron a eliminar mucha comida con el tiempo para encontrar alivio, me llevaron (sin darme cuenta) a disminuir mis niveles de bífidos, y estos niveles bajos, a su vez, empeoraron mi digestión y debilitaron mi sistema inmunitario, etc. Esto explica perfectamente por qué nunca podía pasar un solo día sin tomar probióticos.
It's not the bifidobacteria that's the problem, it's the inflammation. Something happens when you get extremely sick or something that deactivates your entire body.