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DiscussionLet's talk about it: The science of itZeolite

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Zeolite

#1 · February 22, 2019, 1:19 pm

Quote from Guest on February 22, 2019, 1:19 pm
Heard on another site that some recommend zeolite for detox. Any opinions on whether it's worth the risk?

Food Chem Toxicol. 2001 Jul. The effect of the zeolite clinoptilolite on serum chemistry and hematopoiesis in mice.

Zeolites are natural or synthetic crystalline alumosilicates with ion exchanging properties. Supplied in fodder, they promote biomass production and animal health. Our aim was to assess the effects of the natural zeolite, clinoptilolite, on hematopoiesis, serum electrolytes and essential biochemical indicators of kidney and liver function in mice. Two preparations differing in particle size were tested: a powderized form obtained by countercurrent mechanical treatment of the clinoptilolite (MTCp) and normally ground clinoptilolite (NGCp). Young adult mice were supplied with food containing 12.5, 25 or 50% clinoptilolite powder. Control animals received the same food ration without the clinoptilolite. After 10, 20, 30 and 40 days, six animals from each group were exsanguinated to obtain blood for hematological and serum for biochemical measurements as well as to collect femoral bone marrow for determination of hematopoietic activity. Clinoptilolite ingestion was well tolerated, as judged by comparable body masses of treated and control animals. A 20% increase of the potassium level was detected in mice receiving the zeolite-rich diet, without other changes in serum chemistry. Erythrocyte, hemoglobin and platelet levels in peripheral blood were not materially affected.

NGCp caused leukocytosis, with concomitant decline of the GM-CFU content in the bone marrow, which was attributed to intestinal irritation by rough zeolite particles.

The mechanically treated clinoptilolite preparation caused similar, albeit less pronounced, changes. In a limited experiment, mice having transplanted mammary carcinoma in the terminal stage showed increased potassium and decreased sodium and chloride levels, severe anemia and leukocytosis, decreased bone marrow cellularity and diminished content of hematopoietic progenitor cells in the marrow. The clinoptilolite preparations ameliorated the sodium and chloride decline, whereas the effects on hematopoiesis were erratic.

Cellular Zeolite and Anemia          https://www.livestrong.com/article/460566-side-effects-of-cellular-zeolite/

When ingested, zeolites have been found to inhibit granulocyte-macrophage progenitor, or GMP, according to Sloan-Kettering Cancer Center.

GMP is a compound found in human and animal bone marrow that is responsible for the growth and maintenance of healthy bone tissue.

GMP also supports a process called myelopoiesis, which is involved in the production of the cells found in your bone marrow that produce red blood cells.

Inhibiting GMP production in your bone marrow may lead to a decrease in red blood cell production, which may cause conditions such as anemia.

From Sloan-Kettering site       https://www.mskcc.org/cancer-care/integrative-medicine/herbs/zeolite#references-25

Zeolites are hygroscopic compounds with a fine porous cage-like structure that allows for its ion-exchanging, adsorbent, anticaking, chelating, and desiccant characteristics ⁽²²⁾ ⁽²³⁾. Its ion-exchanging properties may alter the ionic composition, pH and buffering capacity of the gastrointestinal tract under conditions of overexposure ⁽²²⁾.

Zeolites may also have both immunosuppressive and immune-stimulating effects, causing a decline of GM-CFU in the bone marrow ⁽²⁵⁾, but also increasing graft-versus-host (GvH) reaction ⁽²⁶⁾. Zeolite can affect brain serotonergic receptor activities of mammary carcinoma-bearing mice ⁽²⁷⁾, but the clinical implications for humans is unclear. Zeolite supplementation did not prolong survival in tumor-bearing animals ⁽²⁵⁾.

Adverse Reactions: Pulmonary fibrosis ⁽²⁹⁾Pneumoconiosis ⁽⁷⁾Mesothelioma: A high incidence in humans exposed to erionite, a type of airborne fibrous zeolite, dust ⁽⁸⁾ ⁽⁹⁾ ⁽¹⁰⁾Aberrant metaphase: Statistically significant increases found in human peripheral blood lymphocytes and cells from exposed mice ⁽⁷⁾Leukocytosis, decline in bone marrow CFU-GM, and myelopoiesis inhibition in animal studies ⁽²⁵⁾Graft-versus-host (GvH) reaction in animals studies ⁽²⁶⁾

Warnings: Erionite, a type of fibrous zeolite, is carcinogenic when inhaled ⁽⁸⁾ ⁽⁹⁾ ⁽¹⁰⁾. Zeolites may also cause local irritation and may alter the ionic composition, pH and buffering capacity of the gastrointestinal tract under conditions of overexposure ⁽²²⁾. Vulkansandkuren, a zeolite product marketed in Europe, was found to contain high levels of heavy metals including arsenic, lead, mercury, cadmium, nickel, copper, and chromium ⁽²⁸⁾. Do not apply liquid zeolite directly into eyes or ears.

·         General: Since zeolites have chelating properties ⁽²³⁾ and may increase gastrointestinal pH ⁽²⁴⁾, they can potentially interact with many prescription drugs when consumed together. In addition, premature disintegration of enteric coated medications may occur with concomitant use.

·         Antibiotics and ferrous drugs: Because zeolites have chelating ⁽²³⁾ and ion-exchanging effects ⁽¹⁶⁾, they can potentially bind to tetracycline derivatives, quinolones, and iron resulting in decreased bioavailability.

·         Chemotherapy: Zeolites may have antioxidant effects ⁽¹⁸⁾ and can potentially interfere with the actions of some chemotherapy drugs.

·         Immunosuppressants: Zeolites may also provoke graft versus host reaction ⁽²⁶⁾ and therefore should not be used with other immunosuppressants or in transplant patients.

Heard on another site that some recommend zeolite for detox. Any opinions on whether it's worth the risk?

Food Chem Toxicol. 2001 Jul. The effect of the zeolite clinoptilolite on serum chemistry and hematopoiesis in mice.

Zeolites are natural or synthetic crystalline alumosilicates with ion exchanging properties. Supplied in fodder, they promote biomass production and animal health. Our aim was to assess the effects of the natural zeolite, clinoptilolite, on hematopoiesis, serum electrolytes and essential biochemical indicators of kidney and liver function in mice. Two preparations differing in particle size were tested: a powderized form obtained by countercurrent mechanical treatment of the clinoptilolite (MTCp) and normally ground clinoptilolite (NGCp). Young adult mice were supplied with food containing 12.5, 25 or 50% clinoptilolite powder. Control animals received the same food ration without the clinoptilolite. After 10, 20, 30 and 40 days, six animals from each group were exsanguinated to obtain blood for hematological and serum for biochemical measurements as well as to collect femoral bone marrow for determination of hematopoietic activity. Clinoptilolite ingestion was well tolerated, as judged by comparable body masses of treated and control animals. A 20% increase of the potassium level was detected in mice receiving the zeolite-rich diet, without other changes in serum chemistry. Erythrocyte, hemoglobin and platelet levels in peripheral blood were not materially affected.

NGCp caused leukocytosis, with concomitant decline of the GM-CFU content in the bone marrow, which was attributed to intestinal irritation by rough zeolite particles.

The mechanically treated clinoptilolite preparation caused similar, albeit less pronounced, changes. In a limited experiment, mice having transplanted mammary carcinoma in the terminal stage showed increased potassium and decreased sodium and chloride levels, severe anemia and leukocytosis, decreased bone marrow cellularity and diminished content of hematopoietic progenitor cells in the marrow. The clinoptilolite preparations ameliorated the sodium and chloride decline, whereas the effects on hematopoiesis were erratic.

Cellular Zeolite and Anemia https://www.livestrong.com/article/460566-side-effects-of-cellular-zeolite/

When ingested, zeolites have been found to inhibit granulocyte-macrophage progenitor, or GMP, according to Sloan-Kettering Cancer Center.

GMP is a compound found in human and animal bone marrow that is responsible for the growth and maintenance of healthy bone tissue.

GMP also supports a process called myelopoiesis, which is involved in the production of the cells found in your bone marrow that produce red blood cells.

Inhibiting GMP production in your bone marrow may lead to a decrease in red blood cell production, which may cause conditions such as anemia.

From Sloan-Kettering site https://www.mskcc.org/cancer-care/integrative-medicine/herbs/zeolite#references-25

Zeolites are hygroscopic compounds with a fine porous cage-like structure that allows for its ion-exchanging, adsorbent, anticaking, chelating, and desiccant characteristics ⁽²²⁾ ⁽²³⁾. Its ion-exchanging properties may alter the ionic composition, pH and buffering capacity of the gastrointestinal tract under conditions of overexposure ⁽²²⁾.

Zeolites may also have both immunosuppressive and immune-stimulating effects, causing a decline of GM-CFU in the bone marrow ⁽²⁵⁾, but also increasing graft-versus-host (GvH) reaction ⁽²⁶⁾. Zeolite can affect brain serotonergic receptor activities of mammary carcinoma-bearing mice ⁽²⁷⁾, but the clinical implications for humans is unclear. Zeolite supplementation did not prolong survival in tumor-bearing animals ⁽²⁵⁾.

Adverse Reactions: Pulmonary fibrosis ⁽²⁹⁾Pneumoconiosis ⁽⁷⁾Mesothelioma: A high incidence in humans exposed to erionite, a type of airborne fibrous zeolite, dust ⁽⁸⁾ ⁽⁹⁾ ⁽¹⁰⁾Aberrant metaphase: Statistically significant increases found in human peripheral blood lymphocytes and cells from exposed mice ⁽⁷⁾Leukocytosis, decline in bone marrow CFU-GM, and myelopoiesis inhibition in animal studies ⁽²⁵⁾Graft-versus-host (GvH) reaction in animals studies ⁽²⁶⁾

Warnings: Erionite, a type of fibrous zeolite, is carcinogenic when inhaled ⁽⁸⁾ ⁽⁹⁾ ⁽¹⁰⁾. Zeolites may also cause local irritation and may alter the ionic composition, pH and buffering capacity of the gastrointestinal tract under conditions of overexposure ⁽²²⁾. Vulkansandkuren, a zeolite product marketed in Europe, was found to contain high levels of heavy metals including arsenic, lead, mercury, cadmium, nickel, copper, and chromium ⁽²⁸⁾. Do not apply liquid zeolite directly into eyes or ears.

· General: Since zeolites have chelating properties ⁽²³⁾ and may increase gastrointestinal pH ⁽²⁴⁾, they can potentially interact with many prescription drugs when consumed together. In addition, premature disintegration of enteric coated medications may occur with concomitant use.

· Antibiotics and ferrous drugs: Because zeolites have chelating ⁽²³⁾ and ion-exchanging effects ⁽¹⁶⁾, they can potentially bind to tetracycline derivatives, quinolones, and iron resulting in decreased bioavailability.

· Chemotherapy: Zeolites may have antioxidant effects ⁽¹⁸⁾ and can potentially interfere with the actions of some chemotherapy drugs.

· Immunosuppressants: Zeolites may also provoke graft versus host reaction ⁽²⁶⁾ and therefore should not be used with other immunosuppressants or in transplant patients.

#2 · February 23, 2019, 12:45 pm

I’d like to hear more about this. Dr. Smith has me on zeolite. Thanks!

#3 · March 31, 2019, 8:15 am

Quote from Guest on February 23, 2019, 12:45 pm

I’d like to hear more about this. Dr. Smith has me on zeolite. Thanks!

Hi How long have you been taking zeolite and have you seen any improvements or changes in conditions?

#4 · March 31, 2019, 9:10 am

What are zeolite?

Where do you buy them ?

Are they the same as clay powder ?? Can we use that ??

When do you take them and how much

Thanks

#5 · March 31, 2019, 12:13 pm

Look in diets and foods under the topic Dr Smith's vitamin a package, page 3.

Josh talks about zeolite and leaves a couple of links

#6 · April 14, 2019, 2:47 am

Quote from Josh on April 14, 2019, 2:47 am

Quote from Guest on February 22, 2019, 1:19 pm

Heard on another site that some recommend zeolite for detox. Any opinions on whether it's worth the risk?

I don't really think there's much risk here. The only problem they've found with zeolite is a type that isn't used for human consumption. The only 'risk' is wasting money a watered-down zeolite liquid or not taking enough. Zeolite is better than clays because clays can release the metals they've absorbed before being excreted. Zeolite holds onto them much better. My kids and I have been taking zeolite for a month and it has been fine. My kids both has some muscle soreness in the first few days. A few weeks in, my younger son complained of stomach ache so he stopped taking it for a few days then resumed at a lower dose and he has been fine so far. I don't know if it was the zeolite or the detox that was causing the stomach ache. I doubt it was the zeolite itself but I guess it's possible. Here are some links to research on zeolit I posted in a different thread:

In this study they compared the detoxing effect in humans of Zeo Health powder compared to some others, showing that it is far superior at removing (chelating) heavy metals from the body.

https://www.zeohealth.com/zeolitestudyek.pdf

Here is a link to some information about safety, manufacturing and quality testing information on the Zeo Health website:

http://www.zeohealth.com/aboutzeolite/zeolitesafety.html

Here is a link is to a recent comprehensive review of in vivo studies of zeolite, showing that it has not been found to be toxic but has been found to have many health benefits.

https://www.frontiersin.org/articles/10.3389/fphar.2018.01350/full

Here is are two studies specifically on zeolite and cancer:

http://zeolitefacts.org/wp-content/uploads/2014/10/cancer-study.pdf

https://www.ncbi.nlm.nih.gov/pubmed/12820427

Here is a website of testimonials of people who have used zeolite:

http://zeolitetestimonials.com/

Here is a link to other research on zeolite:

http://zeolitefacts.org/52-2/

Finally, here is a link to an MA thesis in chemical engineering that examines what happens to zeolite in various acids, including gastric acid (see section 6.2.2). He shows that it is highly stable in gastric acid. There is also a good literature review on zeolite starting on page 17 (section 3.2).

https://core.ac.uk/download/pdf/47253141.pdf

Quote from Guest on February 22, 2019, 1:19 pm

Heard on another site that some recommend zeolite for detox. Any opinions on whether it's worth the risk?

I don't really think there's much risk here. The only problem they've found with zeolite is a type that isn't used for human consumption. The only 'risk' is wasting money a watered-down zeolite liquid or not taking enough. Zeolite is better than clays because clays can release the metals they've absorbed before being excreted. Zeolite holds onto them much better. My kids and I have been taking zeolite for a month and it has been fine. My kids both has some muscle soreness in the first few days. A few weeks in, my younger son complained of stomach ache so he stopped taking it for a few days then resumed at a lower dose and he has been fine so far. I don't know if it was the zeolite or the detox that was causing the stomach ache. I doubt it was the zeolite itself but I guess it's possible. Here are some links to research on zeolit I posted in a different thread:

In this study they compared the detoxing effect in humans of Zeo Health powder compared to some others, showing that it is far superior at removing (chelating) heavy metals from the body.

https://www.zeohealth.com/zeolitestudyek.pdf

Here is a link to some information about safety, manufacturing and quality testing information on the Zeo Health website:

http://www.zeohealth.com/aboutzeolite/zeolitesafety.html

Here is a link is to a recent comprehensive review of in vivo studies of zeolite, showing that it has not been found to be toxic but has been found to have many health benefits.

https://www.frontiersin.org/articles/10.3389/fphar.2018.01350/full

Here is are two studies specifically on zeolite and cancer:

http://zeolitefacts.org/wp-content/uploads/2014/10/cancer-study.pdf

https://www.ncbi.nlm.nih.gov/pubmed/12820427

Here is a website of testimonials of people who have used zeolite:

http://zeolitetestimonials.com/

Here is a link to other research on zeolite:

http://zeolitefacts.org/52-2/

Finally, here is a link to an MA thesis in chemical engineering that examines what happens to zeolite in various acids, including gastric acid (see section 6.2.2). He shows that it is highly stable in gastric acid. There is also a good literature review on zeolite starting on page 17 (section 3.2).

https://core.ac.uk/download/pdf/47253141.pdf

puddleduck has reacted to this post.

#7 · April 14, 2019, 7:56 am

This site says zeolite contains lots of aluminum as well as lead arsenic and uranium.

https://www.naturalnews.com/051761_zeolites_heavy_metals_lab_tests_aluminum.html

Granular seems safe but the powder form that gets absorbed into the blood stream can be dangerous because the toxic metals would also be absorbed.

Personally even in granular form I wouldn’t ingest anything’s that has more metal in them when I’m tryin to detox from metals.

Judy has reacted to this post.

#8 · April 14, 2019, 8:51 pm

Quote from John on April 14, 2019, 7:56 am

This site says zeolite contains lots of aluminum as well as lead arsenic and uranium.

https://www.naturalnews.com/051761_zeolites_heavy_metals_lab_tests_aluminum.html

Granular seems safe but the powder form that gets absorbed into the blood stream can be dangerous because the toxic metals would also be absorbed.

Personally even in granular form I wouldn’t ingest anything’s that has more metal in them when I’m tryin to detox from metals.

Dr G has debunked the natural news zeolite article in his sheet. From what I understand he will make a post on zeolite in his public forum as well. The zeolite he has his patients on is perfectly safe according to the MSDS (safety data sheet).

I personally don't consider naturalnews a reliable source (of anything) and would take anything on there with a bucket of salt.

#9 · April 15, 2019, 12:49 am

Quote from John on April 14, 2019, 7:56 am

This site says zeolite contains lots of aluminum as well as lead arsenic and uranium.

https://www.naturalnews.com/051761_zeolites_heavy_metals_lab_tests_aluminum.html

Granular seems safe but the powder form that gets absorbed into the blood stream can be dangerous because the toxic metals would also be absorbed.

Personally even in granular form I wouldn’t ingest anything’s that has more metal in them when I’m tryin to detox from metals.

There are a lot of problems with that study. Also Mike Adams used that to promote some other product he was selling. One potential risk with zeolite is that it isn't a regulated market, so you can end up with some sketchy or useless products if you don't know what you're looking for. Zeolite adsorbs heavy metals like uraniaum and arsenic. It pulls them out of your body and holds onto them tightly. It doesn't release them into the body, nor will stomach acid dissolve it (see the last study I linked to). If the zeolite isn't properly sourced or prepared, then I suppose it could potentially be harmful. The specific product recommended in the links I shared has been proven safe and effective for something like 20 years now.

puddleduck has reacted to this post.

#10 · April 15, 2019, 3:19 pm

Quote from Liz on April 14, 2019, 8:51 pm

Quote from John on April 14, 2019, 7:56 am

This site says zeolite contains lots of aluminum as well as lead arsenic and uranium.

https://www.naturalnews.com/051761_zeolites_heavy_metals_lab_tests_aluminum.html

Granular seems safe but the powder form that gets absorbed into the blood stream can be dangerous because the toxic metals would also be absorbed.

Personally even in granular form I wouldn’t ingest anything’s that has more metal in them when I’m tryin to detox from metals.

Dr G has debunked the natural news zeolite article in his sheet. From what I understand he will make a post on zeolite in his public forum as well. The zeolite he has his patients on is perfectly safe according to the MSDS (safety data sheet).

I personally don't consider naturalnews a reliable source (of anything) and would take anything on there with a bucket of salt.

@liz
That was just one site. There are many other sites warning about zeolite containing other metals. Andy Cutler is also against claims that it can chelate metals. There are many on his site that have tried zeolite with very bad side effects. Whether it was a bad manufacturer or not, it's just a risk I'm not willing to take. With anything, just pay attention to how you feel when using it.

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