I needed to disable self sign-ups because I’ve been getting too many spam-type accounts. Thanks.
Accutane is associated with dysbiosis, malabsorption and signs of dysimmunity by way of progressive atrophy of the jejunal mucosa and has long-lasting consequences
"Isotretinoin (Accutane) is associated with dysbiosis, malabsorption (with visceral fat decrease) and signs of dysimmunity. Symptoms develop more than 20 years after the intake of the medication taken at usual range and duration. A facilitating role of Propionibacterium acnes cannot be excluded. Isotretinoin is known to impair stem cells renewal and TLR2 expression in the mucosa of the small gut. These pharmacological effects may induce the progressive atrophy of the jejunal mucosa and its long-lasting consequences. No therapy is available yet. Patients, prescribers and authorities should be aware of this adverse event which incidence is high (2.6% of outward gastroenterological consultations) especially when multi-annual surveillance for several years are expected."
I am leaning towards this being the main reason us who were Accutaned experience such catastrophic after effects, perhaps by way of overloading the liver, which is a known contributor to SIBO and other gut disorders.
Have others here discovered SIBO/dysbiosis etc and treated it?
I remember there was a user here, @bludicka who seemed to have treated their issues, they never came back here at least..
The thread "Tim's log" have a comment about himself using herbal antibiotics for what sounded like Small Intestinal Bacterial Overgrowth (SIBO), comment #219:
https://ggenereux.blog/discussion/topic/tims-log/?part=22
In that comment Tim mentions this 2014 study called :
"Herbal Therapy Is Equivalent to Rifaximin for the Treatment of Small Intestinal Bacterial Overgrowth"