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Alterations to DNA. Any thoughts?

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Quote from Orion on April 5, 2019, 4:07 am

Starting 5th month of low A with rice and beef for 3 meals a day on April 1st, before this I was still getting maybe ~150IU carotenoids from low VA fruit, wheat, oats for the first 4 months.

Started using 750mg activated charcoal first thing in the morning, and teaspoon of zeolite before bed on April 1st as well

My skin has gotten really bad this week, which cannot be a coincidence.  Garret mentioned in a article that carotenoids are cleared first(my hand and feet are no longer orange), so I suspect I am dumping preformed retins now or the zeolite is helping the purge?  Sleep still not improving either.

Thank you Orion for letting me know about the zeolite and/or charcoal triggering a reaction.   Hopefully you're dumping A and its a detox reaction.   So your sleep hasn't improved at all since starting 5 months ago?  That is one of things I struggle the most with too.  Please report your success or lack of success with the zeolite or charcoal if you keep taking them.  If I try zeolite, I'll probably start with a very low dose.  I did try charcoal early on but wasn't sure what to think of it so I quit.

Quote from romaine on April 5, 2019, 5:19 am
Quote from Orion on April 5, 2019, 4:07 am

Starting 5th month of low A with rice and beef for 3 meals a day on April 1st, before this I was still getting maybe ~150IU carotenoids from low VA fruit, wheat, oats for the first 4 months.

Started using 750mg activated charcoal first thing in the morning, and teaspoon of zeolite before bed on April 1st as well

My skin has gotten really bad this week, which cannot be a coincidence.  Garret mentioned in a article that carotenoids are cleared first(my hand and feet are no longer orange), so I suspect I am dumping preformed retins now or the zeolite is helping the purge?  Sleep still not improving either.

Thank you Orion for letting me know about the zeolite and/or charcoal triggering a reaction.   Hopefully you're dumping A and its a detox reaction.   So your sleep hasn't improved at all since starting 5 months ago?  That is one of things I struggle the most with too.  Please report your success or lack of success with the zeolite or charcoal if you keep taking them.  If I try zeolite, I'll probably start with a very low dose.  I did try charcoal early on but wasn't sure what to think of it so I quit.

Sleep has actually improved a lot, but its not perfect yet.   8-9hrs uninterrupted is the goal, I can usually get about 5hrs now without waking some nights, then fall back asleep.  But I wake up in mornings much more energized now then in the last 15yrs, that is a huge improvement.

Grant healed without AC and zeolite, so probably not needed, but will report back if I stop.

Quote from ggenereux on April 4, 2019, 10:33 am

Hi Romaine,

The very functional definition of vitamin A’s action is for the retinoic acid form of it to bind with DNA and subsequently cause gene “expressions”.

So, depending on a ton of individual variables and factors, it could take a long time to recover from its overdose.  Although diet alone is not a quick-fix, it’s the only fix we know of right now. For most people it took many years of slow accumulation to get into the toxic state. Therefore, we should expect it to take a long time to recover; thinking two or more years is not unreasonable.

There are other people sharing their experiences here regarding foods and supplements (such as zinc, vitamin C, and vitamin D,E too) that might help in accelerating one’s recovery. Please apply your own good judgement on it. Obviously, what’s really needed is an antidote.

 

As to some people finding vitamin D helpful: I'm confused. Is there a consensus as to whether D3 is good or bad on the detox? Also, do we need a source of omega-3 fats? I've been avoiding fish, but sardines have no vit. A and lots of omega 3. Are they OK?

Quote from Judy on May 13, 2019, 3:24 pm
Quote from ggenereux on April 4, 2019, 10:33 am

Hi Romaine,

The very functional definition of vitamin A’s action is for the retinoic acid form of it to bind with DNA and subsequently cause gene “expressions”.

So, depending on a ton of individual variables and factors, it could take a long time to recover from its overdose.  Although diet alone is not a quick-fix, it’s the only fix we know of right now. For most people it took many years of slow accumulation to get into the toxic state. Therefore, we should expect it to take a long time to recover; thinking two or more years is not unreasonable.

There are other people sharing their experiences here regarding foods and supplements (such as zinc, vitamin C, and vitamin D,E too) that might help in accelerating one’s recovery. Please apply your own good judgement on it. Obviously, what’s really needed is an antidote.

 

As to some people finding vitamin D helpful: I'm confused. Is there a consensus as to whether D3 is good or bad on the detox? Also, do we need a source of omega-3 fats? I've been avoiding fish, but sardines have no vit. A and lots of omega 3. Are they OK?

Hi Judy,

I have read reports of low va dieters reporting normalisation of D levels from low despite stopping supplementation. I dont get much sun so I take a small amount of D when I remember, I would definitely caution against taking larger amounts though.

In nature the important nutrients dha, iodine and selenium usually come packaged with a bit of VA. Early humans ate insects, eggs and reptiles whole, they got these nutrients in plentiful amounts. Seafood provides these nutrients but most seafood is quite high in VA unfortunately :-/

You have to be careful with assuming the nutritional breakdown of the food you are looking at is correct. I think you will find that sardines have a reasonable amount of VA. Scallops with the roe off have very low levels of VA and are very nutritious. Squid is low VA too.

I have noticed that there is a lot of conflicting info in the various nutrient data bases. Is there one that you think if reliable? I've been using http://www.nutritiondata.self.

I like this one because it shows pro-vitamin breakdown too.

https://www.nutritionvalue.org/Fish%2C_drained_solids_with_bone%2C_canned_in_oil%2C_Atlantic%2C_sardine_nutritional_value.html

 

Quote from Judy on May 14, 2019, 8:43 am

I have noticed that there is a lot of conflicting info in the various nutrient data bases. Is there one that you think if reliable? I've been using http://www.nutritiondata.self.

nutritiondata uses the usda database. Often the VA will say 0 for some foods eg beef fat. This does not mean it is necessarily zero, often they haven't measured it. Unfortunately they dont make this clear.

Quote from tim on May 14, 2019, 7:41 am
Quote from Judy on May 13, 2019, 3:24 pm
Quote from ggenereux on April 4, 2019, 10:33 am

Hi Romaine,

The very functional definition of vitamin A’s action is for the retinoic acid form of it to bind with DNA and subsequently cause gene “expressions”.

So, depending on a ton of individual variables and factors, it could take a long time to recover from its overdose.  Although diet alone is not a quick-fix, it’s the only fix we know of right now. For most people it took many years of slow accumulation to get into the toxic state. Therefore, we should expect it to take a long time to recover; thinking two or more years is not unreasonable.

There are other people sharing their experiences here regarding foods and supplements (such as zinc, vitamin C, and vitamin D,E too) that might help in accelerating one’s recovery. Please apply your own good judgement on it. Obviously, what’s really needed is an antidote.

 

As to some people finding vitamin D helpful: I'm confused. Is there a consensus as to whether D3 is good or bad on the detox? Also, do we need a source of omega-3 fats? I've been avoiding fish, but sardines have no vit. A and lots of omega 3. Are they OK?

Hi Judy,

I have read reports of low va dieters reporting normalisation of D levels from low despite stopping supplementation. I dont get much sun so I take a small amount of D when I remember, I would definitely caution against taking larger amounts though.

In nature the important nutrients dha, iodine and selenium usually come packaged with a bit of VA. Early humans ate insects, eggs and reptiles whole, they got these nutrients in plentiful amounts. Seafood provides these nutrients but most seafood is quite high in VA unfortunately :-/

You have to be careful with assuming the nutritional breakdown of the food you are looking at is correct. I think you will find that sardines have a reasonable amount of VA. Scallops with the roe off have very low levels of VA and are very nutritious. Squid is low VA too.

Thank you, Tim.

Quote from Curious Observer on May 14, 2019, 8:58 am

I like this one because it shows pro-vitamin breakdown too.

https://www.nutritionvalue.org/Fish%2C_drained_solids_with_bone%2C_canned_in_oil%2C_Atlantic%2C_sardine_nutritional_value.html

 

Curious Observer: The Nutrition data.com site gives the RAE too if you go to the drop-down menu. They do seem to have some mistakes and blanks, though. I guess the sardines are out.

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