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Fruit and Vitamin C effects on VA Detox
I have been hearing recently that vitamin C as well as polyphenols may have negative implications as far as detoxing from vitamin A goes. Grant do you know anything in regards to this subject? I am curious because I have removed almost all VA from my diet but still consume a large amount of fruit. Sometimes for both breakfast and dinner. Thanks.
Ok no worries. Thanks for the response.
@joshz About the polyphenols, they are thiamine antagonists:
“Heat-stable thiamine antagonists occur in several plants; ferns, tea, betel nut. They include polyphenols; these and related compounds are found in blueberries, red currants, red beets, brussel sprouts, red cabbage, betel nuts, coffee and tea (Hilker and Somogyi, 1982). They react with thiamine to yield the non-absorbable thiamine disulfide. In addition, some flavonoids have been reported to antagonize thiamine as well as haemin in animal tissues. (See Table 15).”
Source: http://helid.digicollection.org/en/d/Js2900e/8.2.html - “Anti thiamine factors”
So, I avoid drinking tea, eating chocolate or berries at the same time as taking my thiamin supplement or eating high-thiamin foods.
Another interesting interaction with thiamine:
“Vitamin C appears to play a protective role if it is consumed together with thiamine. In animal studies the addition of large amounts of vitamin C to a purified diet reduces the requirement for thiamine. Five percent vitamin C added to a thiamine-free diet prevented or delayed the onset of thiamine deficiency signs (Bhuvaneswaran and Sreenivasan, 1962). However, vitamin C supplementation of the diets of thiamine-deficient rats maintained normal ascorbic acid blood levels but was without effect on blood pyruvate levels.“
Source: http://helid.digicollection.org/en/d/Js2900e/8.1.2.html - “Interaction with other micronutrients”
Maybe this is partly due to vitamin C supplements slowing down the production of the DH enzymes, thus lowering the utilization of thiamine for that process? I dunno.
I used to make high-thiamin nut and seed smoothies and energy bars with chocolate in them, which I no longer do because it defeats the purpose. 😝 But it doesn’t seem like most fruits are super duper high in polyphenols:
https://www.healthline.com/health/polyphenols-foods
Blueberries and black currents are the ones to watch out for.
If you enjoy eating a lot of fruit, I would imagine that your body wants it!
It’s more of a concern if you are consuming handfuls of blueberry Brookside chocolates along with your thiamin supplements and morning coffee or something. 😝
Wow @puddleduck that was super good info! Thank you. Blueberries were intact a staple of my fruit meals in the past so I will change that now 🙂 Guess its time to find the best low polyphenol fruits.