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Grant's new Diabetes Blog Post
Quote from puddleduck on August 6, 2020, 10:47 am@lil-chick That makes a LOT of sense. And yeah, the only type one diabetic I know was always skinny (and still is), however the type twos in my life all have rolls or big belleys. I am guessing the lack of body fat is one reason I developed CFS/ME and mental illness as a teen. 🧠 Wish I knew why the VA (if it does work as we suspect) goes to the bones and joints in this person, or the pancreas in that person.
I had a similar situation. I was always a skinny child but then went on to develop an eating disorder so likely impeded any attempt my body made to put on protective fat. Developed CFS and mental health problems. I too have wondered if my natural body shape and perhaps also me forcing low weight later (no way of knowing if my body would have accumulated protective fat) have made my health problems from VA toxicity worse.
Quote from Arena on August 4, 2020, 1:04 pm@orion: hope you are right, because I feel like a zombie 😀 think I’m gonna ease down on the running for a couple of days, though!
@jiri I had a bad reaction after I tried some low fat ground beef one day, but I wasn’t sure what the cause was as there were other factors (e.g. air pollen was high that day), but I might try again. I was under the impression that the expensive stuff was quality, hence Grant’s choice of beef.
@are Can I ask what was your reaction? Some (very few) are allergic to red meat after a tick bite. https://www.webmd.com/allergies/news/20140813/tick-bites-red-meat-allergy
Also, ground beef is high in histamine which can cause problems.
Quote from tim on August 4, 2020, 4:32 pmvA intake hasn't gone up in accordance with an increase in diabetes though. I think it's possible that carotenoid consumption has steadily grown but not total vitamin A intake. One of the studies that Garrett Smith found was of rates of Hypervitaminosis A in NZ in the 1960s. Hypervitaminosis A was common, butter intake was high and many took fish liver oil back then. Hypervitaminosis A has been common for a long time, it's not a change in total vA intake that is purely responsible for an increase in diabetes.
It could easily tie in though. Hypothyroidism slows down vA metabolism, if that has increased then that could explain it. Perhaps the cause is a medication that blocks vA metabolism. One in six americans are now on some type of psychiatric medication. Medication's have such a profound impact on physiology, I think they must be considered a prime suspect. Or perhaps vaccinations play a role?
Did pesticides or toxins from plastics like BPA increase in the food supply in that time?
Another thing to consider is car exhaust, with the switch to unleaded petrol cars started emitting a lot of benzene.
Increased rates of illness are possibly increasing due to inherited poor health. It becomes very hard to find the cause. That's why I prefer to look at the direct effects of things rather than statistics.
One thing is clear, thing are getting worse...
I think one of the key players is glyphosate. Glyphosate suppresses P450 enzymes, which are responsible for breaking down cellular retinoic acid. Interesting you should mention vaccines, because I recently came across some information indicating that vaccinations can also suppress P450 enzymes. This comes from the website of a New Zealander, no less: http://www.beyondconformity.co.nz/about-the-trust
Glyphosate is not the only thing we spray on our food that is bad. Atrazine also messes with RA metabolism, increases RALDH that turns retinaldehyde to retinoic acid and downregulates RBP production: https://peerj.com/preprints/2880.pdf
You are also right about SSRIs. There are other medications as well--birth control being a big one. Garrett has dug into this pretty extensively and shown that there are a lot of things that exacerbate vitamin A toxicity: https://nutritionrestored.com/blog-forum/forum/compounds-that-stimulate-poison-vitamin-a-activity-in-a-bad-way/
I suspect this is all only the tip of the iceberg.
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I think polyunsaturated fats (vegetable oils) are a big part of it -- they cause hypothyroidism and also stress/inflame the pancreatic cells, killing beta cells.
Quote from Tim on August 13, 2020, 10:04 amI think polyunsaturated fats (vegetable oils) are a big part of it -- they cause hypothyroidism and also stress/inflame the pancreatic cells, killing beta cells.
Hi Tim, do you mean linoleic acid itself or do you mean when it is oxidized? I don't doubt you but if you have any studies please post them.
Quote from Arena on August 13, 2020, 1:21 pmSo now I can’t eat my salty chips for calories anymore, I thought sunflower oil was safe, but that is packed with linoleic acid... damn
They often use high oleic sunflower oil which is much better, you can check the fat amounts in the nutritional info to see what kind they used. I wouldn't fill up on chips though, potatoes are high in oxalates and copper and they are a nightshade and deep frying will mean they contain oxidized PUFA as well. Potatoes are nutritious but I dont eat large amounts.
Quote from tim on August 13, 2020, 5:00 pmQuote from Arena on August 13, 2020, 1:21 pmSo now I can’t eat my salty chips for calories anymore, I thought sunflower oil was safe, but that is packed with linoleic acid... damn
They often use high oleic sunflower oil which is much better, you can check the fat amounts in the nutritional info to see what kind they used. I wouldn't fill up on chips though, potatoes are high in oxalates and copper and they are a nightshade and deep frying will mean they contain oxidized PUFA as well. Potatoes are nutritious but I dont eat large amounts.
how many potatoes do you eat in a day ? I like eating them boiled , I think that has an effect on reducing oxalates
I eat about one medium sized potato per day. It's probably fine to eat more than that but I wouldn't make them a staple just as I wouldn't make whole grains a staple. I have a bowl of whole grain cereal for breakfast. I have legumes once every couple of days. Refined grain and meat/chicken/fish are my staples. It's not a good idea to make a staple out of any whole plant food.
Quote from tim on August 14, 2020, 12:07 amI eat about one medium sized potato per day. It's probably fine to eat more than that but I wouldn't make them a staple just as I wouldn't make whole grains a staple. I have a bowl of whole grain cereal for breakfast. I have legumes once every couple of days. Refined grain and meat/chicken/fish are my staples. It's not a good idea to make a staple out of any whole plant food.
Tim, what do mean by "refined grains"? White bread, white rice, white flour products such as pasta noodles, and etc.. Also, does it matter if the refined grains are fortified with minerals such as iron, calcium or fortified with B vitamins?