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Long story short: Discovered my Vitamin A issues through smoking cigarettes.
Quote from
Bella on December 7, 2018, 4:09 pm
Quote from
HeyJude on December 7, 2018, 11:15 am
Fascinating. I too have a genetically low conversion rate for beta-carotene, which I discovered by uploading my ancestry data into Self Decode. I have noticed in recent years that I have dislike for many vegetables and an outright aversion to most cruciferous vegetables, except for cauliflower. I had thought that it was because of the sulfur. Anyway it is likely that my daughter inherited this missense gene. She has disabling mental illness and smokes a pack a day.
JudiBlueHen (in case it posts as guest)
That's so interesting Judi! I might try the self decode with my 23&me raw data. I feel I have some type of genetic predisposition to being unable to handle A. My report showed only heterozygous for macular degeneration and homozygous for celiac. I already have celiac and I'm going against conventional wisdom for macular degeneration prevention by avoiding vitamin A. Oddly (or not) my vision keeps improving with time on low A.
Thanks so much for bringing this up.
Quote from
HeyJude on December 7, 2018, 11:15 am
Fascinating. I too have a genetically low conversion rate for beta-carotene, which I discovered by uploading my ancestry data into Self Decode. I have noticed in recent years that I have dislike for many vegetables and an outright aversion to most cruciferous vegetables, except for cauliflower. I had thought that it was because of the sulfur. Anyway it is likely that my daughter inherited this missense gene. She has disabling mental illness and smokes a pack a day.
JudiBlueHen (in case it posts as guest)
That's so interesting Judi! I might try the self decode with my 23&me raw data. I feel I have some type of genetic predisposition to being unable to handle A. My report showed only heterozygous for macular degeneration and homozygous for celiac. I already have celiac and I'm going against conventional wisdom for macular degeneration prevention by avoiding vitamin A. Oddly (or not) my vision keeps improving with time on low A.
Thanks so much for bringing this up.
Patti has reacted to this post.
Quote from Guest on December 10, 2018, 8:27 am
Hi VH - thank you for posting your mechanism for stress increasing vitamin A. I am very convinced that stress does increase vitamin A just from observations with my own health & I've been thinking about this.
Hi Judi & Bella - Ben Lynch's Strategene does 5 BCO1 SNPs (or it did a while back). I have 4/5 red i.e. I'm a slow betacarotene converter (Ben Lynch suggests vitamin A supplementation - err no thank you!) but it does make me wonder if beta carotene is more problematic in a slow converter? Why does body convert betacarotene to retinol? Is it more toxic?
The smoking thing is just so interesting. Thank you everyone for ongoing interesting discussions.
Best wishes Jenny (JAJ)
Hi VH - thank you for posting your mechanism for stress increasing vitamin A. I am very convinced that stress does increase vitamin A just from observations with my own health & I've been thinking about this.
Hi Judi & Bella - Ben Lynch's Strategene does 5 BCO1 SNPs (or it did a while back). I have 4/5 red i.e. I'm a slow betacarotene converter (Ben Lynch suggests vitamin A supplementation - err no thank you!) but it does make me wonder if beta carotene is more problematic in a slow converter? Why does body convert betacarotene to retinol? Is it more toxic?
The smoking thing is just so interesting. Thank you everyone for ongoing interesting discussions.
Best wishes Jenny (JAJ)
Quote from Guest on December 10, 2018, 4:38 pm
Jenny,
The theory of beta carotene being more toxic than A is one I’ve heard before. Personally I don’t know for certain but I’m sure it’s a distinct possibility and probably highly individual. More than ever I’m coming to respect that our unique genetic makeup is very important. I tried for years eating ‘normal’ as in like the people around me i.e. including gluten/dairy/processed foods in an effort to not be orthorexic and I ended up obese with worsening health and found a new appreciation for listening to my body. I actually ate much less calorie wise and yet wound up sick and uncomfortable due to edema and excess weight.
Thanks for including the information on SNP’s! I’ll definitely check into this soon.
I went on an inadvertent low A diet in 2017 and loss 40 pounds. I never understood why that happened until reading Grants books.
Jenny,
The theory of beta carotene being more toxic than A is one I’ve heard before. Personally I don’t know for certain but I’m sure it’s a distinct possibility and probably highly individual. More than ever I’m coming to respect that our unique genetic makeup is very important. I tried for years eating ‘normal’ as in like the people around me i.e. including gluten/dairy/processed foods in an effort to not be orthorexic and I ended up obese with worsening health and found a new appreciation for listening to my body. I actually ate much less calorie wise and yet wound up sick and uncomfortable due to edema and excess weight.
Thanks for including the information on SNP’s! I’ll definitely check into this soon.
I went on an inadvertent low A diet in 2017 and loss 40 pounds. I never understood why that happened until reading Grants books.
Quote from Guest on December 11, 2018, 10:53 am
I don't understand what you guys are saying. If you have a poor conversion from beta carotene to vitamin a then would you be able to get away with eating more fruits and vegetable containing that because you wouldn't convert it to vitamin a????
I don't understand what you guys are saying. If you have a poor conversion from beta carotene to vitamin a then would you be able to get away with eating more fruits and vegetable containing that because you wouldn't convert it to vitamin a????
jzuc37 has reacted to this post.
Quote from Guest on December 11, 2018, 10:53 am
I don't understand what you guys are saying. If you have a poor conversion from beta carotene to vitamin a then would you be able to get away with eating more fruits and vegetable containing that because you wouldn't convert it to vitamin a????
It would be the opposite. Free carotenoids are prone to oxidation (which is probably why vegetables contain antioxidants). The body converts them to "vitamin A" to store them safely and prevent oxidative damage. When the body runs out of storage (or can't convert fast enough), health issues develop like autoimmune diseases, diabetes or obesity. I personally don't think carotenoids/vitamin A are the only thing causing the health issues today, but they seem to play a major part.
Quote from Guest on December 11, 2018, 10:53 am
I don't understand what you guys are saying. If you have a poor conversion from beta carotene to vitamin a then would you be able to get away with eating more fruits and vegetable containing that because you wouldn't convert it to vitamin a????
It would be the opposite. Free carotenoids are prone to oxidation (which is probably why vegetables contain antioxidants). The body converts them to "vitamin A" to store them safely and prevent oxidative damage. When the body runs out of storage (or can't convert fast enough), health issues develop like autoimmune diseases, diabetes or obesity. I personally don't think carotenoids/vitamin A are the only thing causing the health issues today, but they seem to play a major part.
Quote from Guest on December 11, 2018, 12:50 pm
Ok I see your point.
Last year after watching many videos about the benefit of eating animal liver I started incorporating it into my diet. Few months later I had dry skin and seborrheic dermatitis on my scalp and beard area. ( I am 32 and never had that problems prior.) I never connected the dots until last week. I had been eating liver twice a week thanks to the YouTube carnivore community raving about it. It's been so long I been trying to solve this and trust me I have tried every cure under the sun. This makes sense to me. I was convinced that liver is healthy and even tried converting my family into organ eaters even though we all hated the taste. My parents always thought it was toxic. I cut out the liver now. I still eat sweet potatoes so I will switch to white.
I remember in the summer time they said the sun (uvb) would help with my condition. The thing it was also pointed out that the sun depletes vitamin a. So I would go tanning then eating liver after. I never saw any progress and my skin got drier and drier.
I am going to try infrared sauna to help with detox. Supplements I take: vitamin D ( conflicted about this one), borage oil (omega6), zinc, magnesium, b6, boron. I also just cut cod liver oil And I think I will throw this one out. My next supplements to try were emu oil and fulvic acid. Not sure now but I will definetly reduce vitamin A from any source.
Ok I see your point.
Last year after watching many videos about the benefit of eating animal liver I started incorporating it into my diet. Few months later I had dry skin and seborrheic dermatitis on my scalp and beard area. ( I am 32 and never had that problems prior.) I never connected the dots until last week. I had been eating liver twice a week thanks to the YouTube carnivore community raving about it. It's been so long I been trying to solve this and trust me I have tried every cure under the sun. This makes sense to me. I was convinced that liver is healthy and even tried converting my family into organ eaters even though we all hated the taste. My parents always thought it was toxic. I cut out the liver now. I still eat sweet potatoes so I will switch to white.
I remember in the summer time they said the sun (uvb) would help with my condition. The thing it was also pointed out that the sun depletes vitamin a. So I would go tanning then eating liver after. I never saw any progress and my skin got drier and drier.
I am going to try infrared sauna to help with detox. Supplements I take: vitamin D ( conflicted about this one), borage oil (omega6), zinc, magnesium, b6, boron. I also just cut cod liver oil And I think I will throw this one out. My next supplements to try were emu oil and fulvic acid. Not sure now but I will definetly reduce vitamin A from any source.
Donald has reacted to this post.
Quote from Guest on December 11, 2018, 1:09 pm
Quote from Guest on December 11, 2018, 12:50 pm
Ok I see your point.
Last year after watching many videos about the benefit of eating animal liver I started incorporating it into my diet. Few months later I had dry skin and seborrheic dermatitis on my scalp and beard area. ( I am 32 and never had that problems prior.) I never connected the dots until last week. I had been eating liver twice a week thanks to the YouTube carnivore community raving about it. It's been so long I been trying to solve this and trust me I have tried every cure under the sun. This makes sense to me. I was convinced that liver is healthy and even tried converting my family into organ eaters even though we all hated the taste. My parents always thought it was toxic. I cut out the liver now. I still eat sweet potatoes so I will switch to white.
I remember in the summer time they said the sun (uvb) would help with my condition. The thing it was also pointed out that the sun depletes vitamin a. So I would go tanning then eating liver after. I never saw any progress and my skin got drier and drier.
I am going to try infrared sauna to help with detox. Supplements I take: vitamin D ( conflicted about this one), borage oil (omega6), zinc, magnesium, b6, boron. I also just cut cod liver oil And I think I will throw this one out. My next supplements to try were emu oil and fulvic acid. Not sure now but I will definetly reduce vitamin A from any source.
seems like borage has some carotenoids too https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008743/
Quote from Guest on December 11, 2018, 12:50 pm
Ok I see your point.
Last year after watching many videos about the benefit of eating animal liver I started incorporating it into my diet. Few months later I had dry skin and seborrheic dermatitis on my scalp and beard area. ( I am 32 and never had that problems prior.) I never connected the dots until last week. I had been eating liver twice a week thanks to the YouTube carnivore community raving about it. It's been so long I been trying to solve this and trust me I have tried every cure under the sun. This makes sense to me. I was convinced that liver is healthy and even tried converting my family into organ eaters even though we all hated the taste. My parents always thought it was toxic. I cut out the liver now. I still eat sweet potatoes so I will switch to white.
I remember in the summer time they said the sun (uvb) would help with my condition. The thing it was also pointed out that the sun depletes vitamin a. So I would go tanning then eating liver after. I never saw any progress and my skin got drier and drier.
I am going to try infrared sauna to help with detox. Supplements I take: vitamin D ( conflicted about this one), borage oil (omega6), zinc, magnesium, b6, boron. I also just cut cod liver oil And I think I will throw this one out. My next supplements to try were emu oil and fulvic acid. Not sure now but I will definetly reduce vitamin A from any source.
seems like borage has some carotenoids too https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008743/
Quote from Guest on December 11, 2018, 1:40 pm
Yea you are right but its a small amount really negligible. I have bigger fish to fry at this point. Eating two full animal liver not to even mention heart and other organs must have overloaded my vitamin a. I think cutting those out might be enough. I will take some charcoal although I am not sure when I am supposed to take it? Seems like timing is important. But my goal isn't to get zero vitamin A. Just reduce drastically.
Yea you are right but its a small amount really negligible. I have bigger fish to fry at this point. Eating two full animal liver not to even mention heart and other organs must have overloaded my vitamin a. I think cutting those out might be enough. I will take some charcoal although I am not sure when I am supposed to take it? Seems like timing is important. But my goal isn't to get zero vitamin A. Just reduce drastically.
Quote from Guest on December 11, 2018, 1:58 pm
Also, just based on observation. A lot of smokers do have good skin especially when they are younger. Rarely do I see smokers with acne or any other blemishes hmmm
Also, just based on observation. A lot of smokers do have good skin especially when they are younger. Rarely do I see smokers with acne or any other blemishes hmmm
Quote from
who_am_i on December 11, 2018, 9:28 pm
Smoking and rosacea:
The relationship between smoking and rosacea is poorly understood. We aimed to conduct the first cohort study to determine the association between smoking and risk of incident rosacea. We included 95,809 women from Nurses’ Health Study II (1991–2005). Information on smoking was collected biennially during follow-up. Information on history of clinician-diagnosed rosacea and year of diagnosis was collected in 2005. We used Cox proportional hazards models to estimate age- and multivariable-adjusted hazard ratios and 95% confidence intervals for the association between different measures of smoking and risk of rosacea. During follow-up, we identified 5,462 incident cases of rosacea. Compared with never smoking, we observed an increased risk of rosacea associated with past smoking (multivariable-adjusted hazard ratio = 1.09, 95% confidence interval: 1.03, 1.16) but a decreased risk associated with current smoking (hazard ratio = 0.65, 95% confidence interval: 0.58, 0.72). We further found that increasing pack-years of smoking was associated with an elevated risk of rosacea among past smokers (P for trend = 0.003) and with a decreased risk of rosacea among current smokers (P for trend < 0.0001). The risk of rosacea was significantly increased within 3–9 years since smoking cessation, and the significant association persisted among past smokers who had quit over 30 years before.
Source: https://academic.oup.com/aje/article/186/1/38/3791463
Smoking and rosacea:
The relationship between smoking and rosacea is poorly understood. We aimed to conduct the first cohort study to determine the association between smoking and risk of incident rosacea. We included 95,809 women from Nurses’ Health Study II (1991–2005). Information on smoking was collected biennially during follow-up. Information on history of clinician-diagnosed rosacea and year of diagnosis was collected in 2005. We used Cox proportional hazards models to estimate age- and multivariable-adjusted hazard ratios and 95% confidence intervals for the association between different measures of smoking and risk of rosacea. During follow-up, we identified 5,462 incident cases of rosacea. Compared with never smoking, we observed an increased risk of rosacea associated with past smoking (multivariable-adjusted hazard ratio = 1.09, 95% confidence interval: 1.03, 1.16) but a decreased risk associated with current smoking (hazard ratio = 0.65, 95% confidence interval: 0.58, 0.72). We further found that increasing pack-years of smoking was associated with an elevated risk of rosacea among past smokers (P for trend = 0.003) and with a decreased risk of rosacea among current smokers (P for trend < 0.0001). The risk of rosacea was significantly increased within 3–9 years since smoking cessation, and the significant association persisted among past smokers who had quit over 30 years before.
Source: https://academic.oup.com/aje/article/186/1/38/3791463
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