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Mushrooms, Beta-Glucans and Bile Excretion
@jiri Have you tried betaine HCL? Which is more potent, pure HCL or betaine HCL?
With betaine capsules I can get up to 10x650mg. Instead, by drinking HCL drops in water the amount of HCL will be less than 2 mg.
I have a very weak stomach acid, by doing the HCL challenge test I have gone up to do 8x650mg and still I haven't felt any burning sensation.
@mattia I tried betaine. pure HCL is much cheaper and because it's liquid I think it works better. But you shouldn't drink it. I use the biggest gelatine capsules where I can fit like 15 drops and eat that capsule with last bites of food.. Now I take it only if I eat bigger meal with meat. You need to find out why you have low stomach acid. Is it chronic stress or deficiency in things like B1, zinc, sodium chloride, potassium, amino acids especially histidine etc.? It could be also from bad eating habits. For example eating in hurry, not chewing your food enough, watching tv, pc, play with phone while eating etc.. I have hard time eating slowly without watching youtube or something.. It's good to use betaine or HCL so you can start absorbing minerals, amino acids again and make your own HCL or when you know you have a lot of stress you can supplement with it, but it's not a good idea take it long term. Maybe if you are 60+ yo at that age I think almost everyone should take hcl and digestive enzymes..
https://atm.amegroups.com/article/view/3396/4247
...
In our study we focused on evaluation of effects of an insoluble, fungi-derived β(1-3)(1-6)-D-glucan as dietary supplement in piglets. We measured the growth, phagocytosis of peripheral blood cells and interleukin 2 (IL-2) and tumor necrosis factor alpha (TNF-α) production after feeding with 15 mg of glucan/kg/day.
Conclusions: Following supplementation, β(1-3)(1-6)-D-glucan has been shown to stimulate growth, phagocytic activity, and IL-2 production. In addition, it significantly lowered the cortisol and TNF-α levels after lipopolysaccharide (LPS(endotoxin)) challenge.
"Highly potent immuno-stimulators:: Glucans in mushroom extract cocktail provide boost
https://www.nutritioninsight.com/news/highly-potent-immuno-stimulators-glucans-in-mushroom-extract-cocktail-provides-boost.html
^^^ Iherb sells this stuff as a supplement.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187869/
In wild-type C. albicans, the outer mannan layer of the wall masks the inner layer of β(1-3)-glucan from exposure and detection by innate immune effector molecules like the C-type signaling lectin Dectin-1
+++
Modulatory role of vitamin A on the Candida albicans-induced immune response in human monocytes
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232755/
Moreover, atRA significantly suppressed the expression of Dectin-1, a major fungal pattern recognition receptor, as well as the Dectin-1-dependent cytokine production.
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Dexamethasone induced inhibition of Dectin-1 activation:
https://www.nature.com/articles/s41598-017-04558-z
(beta-glucans are sugars that could be found in the cell walls of bacteria/fungi/yeasts and some plants, such as oats and barley)
...
β-Glucan, extracted from oat, enhances disease resistance against bacterial and parasitic infections
https://academic.oup.com/femspd/article/35/1/67/529284
The effect of β-glucan, extracted from oats, on the enhancement of resistance to infections caused by Staphylococcus aureus and Eimeria vermiformis was studied in mice. In vitro study using macrophages isolated from the peritoneal cavity showed that β-glucan treatment significantly enhanced phagocytic activity. In vivo study further demonstrated that β-glucan treatment induced a significant (P<0.05) protection against the challenge with 5×108 of S. aureus in mice. Fecal oocyst shedding in the C57BL/6 mice infected with E. vermiformis was diminished by β-glucan treatment by 39.6% in intraperitoneal and 28.5% in intragastric group compared to non-treated control. Patency period was shorter and antigen (sporozoites and merozoites) specific antibodies were significantly (P<0.05–0.01) higher in β-glucan-treated group compared to non-treated control group. There were an increasing number of splenic IFN-γ-secreting cells in glucan-treated group via intraperitoneal route, which might be responsible for the enhancement of the disease resistance. Glucan treatment was able to effectively change the lymphocytes population (Thy 1.2+, CD4+ and CD8+ cells) in the mesenteric lymph nodes and Peyer's patches in mice infected with E. vermiformis. In conclusion, the oral or parenteral oat β-glucan treatment enhanced the resistance to S. aureus or E. vermiformis infection in the mice.
Damn, I recently had a bad reaction to honey mushrooms. Googling, I found that they have no formed vitamin A, but a lot of carotenoids. In general, the color rule works best: eat white.
I enjoy eating mushrooms. I was probably eating 150-200 grams of mushrooms a day throughout detox. May have been helpful for some B vitamins that I wasnt getting from high beef. The oats seemed to 'speed' up detox too much for me and was on verge of headaches. I'm better now with oats (and beans incidentally) after eating eggs for more choline. Many years ago I ate loads of oats for what might have been high vit A toxicity and they were very helpful until I overdid them as usual.