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Niacin

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@jiri  I’ll look into it, thanks. Anecdotally, I have heard that people taking niacin do much better on nicotinic acid than niacinamide.

Quote from John on March 17, 2024, 9:22 am
Quote from puddleduck on March 17, 2024, 4:29 am

Yeah, I’m an over-methylator it seems, so I think that’s why I generally responded positively to niacin. Do you think your overall pattern is under-methylation @jiri?

 

Any other reason to believe why you may be an over-methylator?

Are you asking for general information on this subject, @john? If so, check out this article from Catherine Crow:

https://butternutrition.com/signs-of-overmethylation/

I haven't read this whole thread, has this been discussed?

https://www.nih.gov/news-events/nih-research-matters/how-excess-niacin-may-promote-cardiovascular-disease

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Joe2

https://www.orlandohealth.com/content-hub/can-vitamins-be-too-much-of-a-good-thing

This article says that too much vitamin b3/niacin may cause liver damage, increased blood sugar and lower blood platelets. 

Also mentions effects of too much vitamin A, vitamin D, B6 and vitamin C.  

Quote from Arios on January 19, 2024, 4:22 am

I have two theory regarding G.Smith sudden gain of interest in high dose Niacin supplementation

The first one is to balance the zinc intake of his protocol/diet, because too much zinc from your diet or via supplementation can act like a neurotoxin and deplete amongs other things your NAD+ level. 

The second hypothesis is that he will certainly in the near future want to sell his own 100% Nicotinic acid supplement.

 High doses of niacin can induce serotonin syndrome and insulin resistance.I find that is a bit irresponsible for G.Smith to recommend a "vitamin" that causes so many problems without a warning.

 

 

Links to pubmeds or scihubs or whatever on those problems?

The defense to this article allegations against nicotinic acid claimed by Garrett Smith is that nicotinic acid is different than all the other forms of niacin and that nicotinic acid does not cause all these problems.

https://www.nih.gov/news-events/nih-research-matters/how-excess-niacin-may-promote-cardiovascular-disease

Any replies to that argument are appreciated.

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