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Our Family - Behavioral Outburts, Acne, Urinary Problems, Hormones...Oh My!
@Neilky - if you haven't done so already (and even if you have) I'd suggest reading Chapter 5 of Poisoning for Profits - The Botched Deficiency Experiments. I think Grant covered this Retinol-Retinoic Acid-Lard-Casein-Butter subject in sufficient detail to give pause to any considerations of consuming these foods, relative contents of Retinol-Retinoic Acid notwithstanding. It could be the most important thing he's written to date. I'm using it as a hand-out, along with Chapter 3 to initiate discussion and understanding with students in medical school, practitioners of all kinds, and lay-persons who express any interest at all. I've found recently there is no way to get the whole point across in simpler hand-outs. Even though the printing-costs are higher, I figure if I'm serious about conveying the story well, and spending the time to generate a greater curiosity to get people to visit the website, then it makes the best sense compared to anything I could ever summarize. Standing back and thinking about how Grant put all of that together, and how much time it must have consumed to make all of the necessary connections and locate all the papers, just continues to amaze me every time I re-read them. I can't help but think that his previous toxicity left him with an expanded number of highly-functional brain cells. I can really sense a major cognitive improvement in the last year, so I'm taking this even much more seriously now than I already have. When I performed the Avogadro's Number and Molar Mass calculations a week or two ago, it just blew my mind regarding how many actual molecules we are talking about, even at microgram levels of either of them. I've been eating a lot of ground lamb of late and one nice thing about that is being able to do a low-temp cook in a bit of water, and then draining-off the fat. That just gave me an idea that it will be interesting to see if there's fluorescence in either portion. I'll make it a point to talk with the folks at the BioNutrient Food Association to see if their proto-type meter picks up on the Retinol content of foods. That would be pretty cool. It's being produced in Ann Arbor at some specialty lab. Thanks for reading and best of sailing to you.
Yes, I have read it and it is amazing stuff. I'm now having beef burgers and decaf for breakfast after 4 years of bacon and eggs with a bullet proof coffee! There is no arguing with egg and butter having vitamin A. Pork seems contentious?
Quote from Neilky on October 8, 2019, 5:50 amI had suffered from cracked lips for a long time but that has resolved. I would only have to drink a bullet proof coffee and my lips would peel. I have checked my blood glucose and don't think that is an issue. When I started carnivore for a month I ate a lot of fatty meat and my vision was almost instantly blurry. My eye floaters also became much more noticeable. After ditching carnivore for keto my problems persisted and having ditched Keto my blurry vision has slowly improved. I was eating nearly a full bar of butter a day at times.
I still have peeling lips and have not given up my coffee with milk.... perhaps it is time. Thanks for posting this (regarding the bullet-proof coffee, which maybe people don't know, contains typically BUTTER and MCT oil). It really could be about the topical dose of the milk! I suspected that waaay back, but it is hard to change sometimes.
@Orion - I found something odd while doing Thiamine research. When I did a search on PubMed for "Thiamine and Eczema" it yielded quite a few papers from the 50's, 60's and 70's with no abstracts available. Almost all of them were Russian research. I don't know if that's common on PubMed due to age of study or language considerations. It just seems really strange that if the Russian researchers were all-over-this Thiamine angle way back then, that there wouldn't be a slew of papers from other countries following the same line of thought. The old papers end in 1978 and then there's a gap until 2019. There's only 17 papers in total. Even one of the 2019 papers doesn't have an abstract. I'm going to run the same kind of search against other autoimmune conditions and see if there's any commonality in results. Wonder if the Russians were making any connections to Retinoic Acid depleting Thiamine, (on top of it ruining stem cell processes). The Folate paper from the other day comes to mind. Searching "Thiamine Deficiency and Eczema" only yields 3 papers, all of which are on the other search.
Here's some of the titles.
Use of vitamin B1 in therapy of eczema and some other skin diseases
Therapeutic importance of vitamin B1 in treatment of eczema and other dermatoses
Vitamin B1 in eczema and neurodermatitis in children
VITAMIN B-1 AND B-2 CONCENTRATION IN THE BLOOD AND SKIN OF PATIENTS WITH ECZEMA
Vitamin therapy of Eczema in children
The effect of prolonged loading with vitamins B1 and C on the level of pyruvic acid in the urine of patients with eczema
The role of disorders of metabolism of vitamin B1, vitamin C and of the trace element copper in the pathogenesis of eczema
The effect of different methods of treatment on the urinary excretion and concentration of vitamin "C" in the blood of microbial eczema patients
Vitamin B 1 metabolism disorders in microbial eczema
Activity of certain enzymes and dynamics of the content of vitamins C, B1, and A in blood serum in patients with eczema
Role of change in the blood content of trace elements--copper, zinc, manganese and vitamins C, B1, and A in the pathogenesis of eczema
Disorders of some metabolic processes in patients with microbial eczema
Transketolase activity as a parameter for the vitamin B1 provision in some dermatoses (herpes zoster, psoriasis, drug eruptions, excema, and urticaria
Here's the 2019 paper without an abstract.
Zinc deficiency and severe protein-energy malnutrition in a child with atopic eczema.
Author information
- 1 - Department of Dermatology, The James Cook University Hospital, Middlesbrough, North Yorkshire, UK.
- PMID:30062797
"Thiamine and Crohn's" search had this one that might be helpful.
Acta Med Scand. 1985;218(1):129-31.
Aggravation of thiamine deficiency by magnesium depletion. A case report.
Dyckner T, Ek B, Nyhlin H, Wester PO.
Abstract
A patient with Crohn's disease and long-standing diarrhea resulting in a combined thiamine and magnesium deficiency is presented. Despite massive doses of thiamine i.v., the symptoms of thiamine deficiency could not be suppressed until the magnesium deficiency was corrected as well. This case report emphasizes the dependence of thiamine on magnesium for an adequate function in the body.
PMID:4050546
Good stuff, I wonder if throwing the other names thiamine tetrahydrofurfuryl disulfide TTFD would help in searching or Cocarboxylase (active thiamine). Thanks
I wonder if that is retinol being mobilised from the liver because of the fat?
What evidence have you seen for fat mobilizing retinol from the liver? Ethanol mobilizes retinol by interacting with various aspects of liver physiology, the exact mechanisms aren't known. If drinking alcohol doesn't give you eye symptoms then maybe that suggests that pork belly mobilizing retinol is less likely to be the cause?
Also when you have eaten liver without much fat have you experienced eye symptoms? Because if you didn't that would rule out exogenous VA as causing the symptoms as well.
If indeed fat does mobilize retinol from the liver I don't see that as a negative or a positive without further information.
Quote from tim on October 8, 2019, 3:43 pmI wonder if that is retinol being mobilised from the liver because of the fat?
What evidence have you seen for fat mobilizing retinol from the liver? Ethanol mobilizes retinol by interacting with various aspects of liver physiology, the exact mechanisms aren't known. If drinking alcohol doesn't give you eye symptoms then maybe that suggests that pork belly mobilizing retinol is less likely to be the cause?
Also when you have eaten liver without much fat have you experienced eye symptoms? Because if you didn't that would rule out exogenous VA as causing the symptoms as well.
If indeed fat does mobilize retinol from the liver I don't see that as a negative or a positive without further information.
Good points Tim and thanks for responding. I have no evidence at all and that statement "from the liver" is very speculative. All I actually know is I get blurry vision from high fat consumption. My blood sugar never really spikes or falls ranging from 6.0 to 5.2, however, Keto has increased my fasting blood glucose to approx 5.8. Tthe morning after alcohol it will be down at 5.2 and good vision. My fasting level is usually the highest level for the day as once I eat my pancreas shoots insulin and it comes down. Highly strange I know, so despite the small movement, I can't rule out BS as a cause in one way or another. Maybe fat increases insulin resistance in me, but the blood sugar won't rise after consuming fat.
I am pretty sure the same thing happened with beef fat also so can't point the finger at pork. The very first time I got blurred vision, I had just consumed a massive portion of pork belly, on my first day of carnivore diet, it was so profound I will never forget it. Of course I put it down to fat adaptation as is the nature of Keto chat. I never had an issue prior.
Your point with regards to consuming liver is excellent. No, I would not have the same immediate effect. However, how is that exogenous vit A metabolized. It has to pass through a series of steps in order to enter the blood stream, how long does that take? I don't have that answer.
My bro-science theory is based on the fact that Vit A is fat soluble and that consuming a high fat meal emulsifies the Vit A in the body (liver/blood) making it more bioavailable. This will increase Vit A toxicity symptoms while the fat is in circulation... I have a high serum Retinol of 3.0 which is high on the scale, pointing to saturation.