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The 1945 study: "Activated carbon diets and early vitamin A deficiency. Application to the preparation of diets without vitamin A" (translated from French)
Rat study has experimental control. Change one variable each time (carbon or Vitamin A).
No/low Vitamin A and rat die. Add carbon and die faster. Add Vitamin A and rat don't die even with carbon. Vitamin A save rat from carbon.
Mold patient has no experimental control. Take 2 tsp clay for 3 years, then 4 tsp clay for 2.5 years, then charcoal (no amount said) for 4 years. Total years of "experiment" is 9.5. Nothing else change in 9.5 years of life? You believe charcoal story but not Vitamin A study? Strange...
Charcoal extends lifespan of old rats:
"The effect of repeated courses of enter0sorption upon the mean and maximal lifespan
and some functional and metabolic indices was determined in 28-month-old Wistar rats. Significant increase of mean and maximal lifespan of old rats was noted at certain regimens of enterosorption. The experimental animals demonstrated less marked age-related structural and ultrastructural changes in the liver, kidneys, myocardium, intestines, pancreas, as compared with
control animals. Enterosorption leads to a reduction of pentobarbital-induced sleep, decrease of
content of cytochrome P-450, blood cholesterol and triglycerides, cardiac and cerebral tissue
cholesterol, total lipids, liver cholesterol and triglycerides. Enterosorption was found to increase
the RNA and protein biosynthesis in the liver, kidneys and adrenals of old animals."
Highly activated charcoal protected rats from chemotherapy:
AC2 administration promoted significant myeloprotective effect: 1.5-fold increase in leukocytes, 2-fold in neutrophils, 1.5-fold in lymphocytes, and 1.23-fold in platelet count compared to the experimental Melphalan Group. At the same time, AC1 administration resulted in a slight increase in haematological parameters. Both ACs positively corrected important, but diverse, components of oxidative stress. They significantly reduced oxidative modification of blood and liver proteins (especially the AC1 form), normalized the level of reduced glutathione, pro-oxidant/antioxidant ratio and other markers. For some markers, such as ROS production in blood plasma, the use of enterosorbents resulted in non-significant a shift towards normal parameters. Conclusions: Oral activated carbon adsorbents reduce oxidative stress intensity and myelotoxicity; they can be promising means to combat the adverse effects of chemotherapy in clinical practice.
Quote from Janelle525 on February 7, 2024, 5:21 pmCharcoal extends lifespan of old rats:
"The effect of repeated courses of enter0sorption upon the mean and maximal lifespan
and some functional and metabolic indices was determined in 28-month-old Wistar rats. Significant increase of mean and maximal lifespan of old rats was noted at certain regimens of enterosorption. The experimental animals demonstrated less marked age-related structural and ultrastructural changes in the liver, kidneys, myocardium, intestines, pancreas, as compared with
control animals. Enterosorption leads to a reduction of pentobarbital-induced sleep, decrease of
content of cytochrome P-450, blood cholesterol and triglycerides, cardiac and cerebral tissue
cholesterol, total lipids, liver cholesterol and triglycerides. Enterosorption was found to increase
the RNA and protein biosynthesis in the liver, kidneys and adrenals of old animals."
Read study, not abstract. Math is wrong, no reported variance, not all results reported!
Control age mean (at 50%, 80%, 100% mortality):
937, 972, 993 days.
Carbon Group 2 age mean (at 50%, 80%, 100% mortality):
977, 1023, 1055 days.
Group 2 divided by Control in percent is:
104%, 105%, 106%
So Group 2 carbon lived ~5% longer (on average but no measure of variance reported). Very small difference. But they say 47%, 41%, and 44% longer? How?!
They say Carbon Group 3 did worse but don't report number days, only percent. No numbers report or mention at all for Carbon Group 4! Did they all die?
Study is on "old animals". Maybe carbon help when body not work good anymore but harm young healthy animal.
Nobody read studies carefully... 🙁
Why did the all rats in this French 1945 study die within 125 days?
The life-span of laboratory rats in captivity is at least 2 years (730 days), see attached table with life development stage for rats taken from this 2021 paper called:
"The laboratory rat: Age and body weight matter"
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564917/
125 /730 = 17 % of some average excpected life span in captivity (this was the rats the lived the longest without any intervention).
How come?
-Certainly some research scientists shouldn't have pets.
@jessica2
You are funny!
Five year old rats having growth spurs 😀
Stand-up comic gets up and asks:
"Hey experts, should I char this food before I eat it?"
researcher 1: "it's the antidote to any poison!"
researcher 2: "blackening your food makes it poisonous!"
(That being said, my garden plants love char. We aren't plants though.)
"Studies show the high efficiency of detoxification therapy (enterosorption) in the complex treatment of various diseases. Due to the selective adsorption of toxins by enterosorbents, in patients the digestive processes are normalized, the condition of the intestinal mucosa, gastrointestinal tract and the immune system is significantly improved, which contributes to the rapid relief of clinical symptoms and improves the prognosis."
"Against the background of the use of enterosorbents in the treatment of allergic diseases a decrease in the severity of skin itching, edema and the activity of skin rashes is noted. In the formation of allergic reactions, in particular food allergies, the development of intestinal dysbacteriosis, which is the cause of the formation of not only food allergy, but also other pathological processes, plays an important role. At normal preserved intestinal barrier function and normal microflora composition, endotoxins enter the bloodstream in small amounts and are detoxified in hepatocytes. In the case of dysbacteriosis, endogenous intoxication is maintained, due to which the permeability of the intestinal wall increases and the effect of adaptive and protective mechanisms weakens, leading to the occurrence of various diseases [47].
Use of enterosorbents is one of the perspective directions in the prevention and treatment of gastrointestinal diseases of various etiologies. The use of sorbents allows exclude or reduce the intensity of other drug therapy, including antibiotic and hormone therapy [48]."
https://www.sciencedirect.com/science/article/pii/S2215038221001850#bb0170
An interesting thing they said about zinc: A deficiency in zinc causes an apparent demand for vitamin A!!!!!!!!!!!!!!!
Quote from lil chick on February 8, 2024, 5:36 amStand-up comic gets up and asks:
"Hey experts, should I char this food before I eat it?"
researcher 1: "it's the antidote to any poison!"
researcher 2: "blackening your food makes it poisonous!"
(That being said, my garden plants love char. We aren't plants though.)
I think burnt food is different right? Charcoal gets 'activated' so that it can adsorb many times more. Charred food is known to be carcinogenic due to AGE's. I've never heard the same about activated charcoal.