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The 1945 study: "Activated carbon diets and early vitamin A deficiency. Application to the preparation of diets without vitamin A" (translated from French)
Zeolites are another option. Well known in the autism community. Here is a good paper on those: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277462/
"The excessive production of ammonia, but also of other gaseous products, including CO2 and H2S, may occur as a consequence of protein-rich or imbalanced diets, or in diverse pathogeneses where excessive protein fermentation occurs, including irritable bowel syndrome, ulcerative colitis, and colorectal carcinogenesis (Hughes and Magee, 2000; Yao et al., 2016). Clinoptilolite has a high affinity toward ammonium and may prove useful in these cases as an adjuvant to the standard therapy (Yao et al., 2016). "
"Consequences of exercise at exhaustion levels include increased number of leukocytes due to the damage of muscle fibers and connective tissue (Morillas-Ruiz and Hernández-Sánchez, 2015) as well as elevated lipid-peroxidation marker MDA in the plasma (Pingitore et al., 2015). It is, therefore, not surprising that a number of professional athletes show gastrointestinal symptoms, which may result in medical problems, infections, and autoimmune disease (Waterman and Kapur, 2012; Oliveira et al., 2014). Interestingly, the supplementation with Panaceo Sport positively influenced the intestinal wall integrity, which was witnessed through decreased concentrations of the tight junction modulator zonulin, a marker of increased intestinal permeability (Lamprecht et al., 2015)."
"Moreover, clinoptilolite incorporated into the diet may be effective in fighting mycotoxins by direct absorption. Affinity toward aflatoxins, zearalenone, ochratoxin, and the T2 toxin was proven in vitro in the presence of aminoacids and vitamins, where the latter were not absorbed by the clinoptilolite material (Tomasevic-Canovic et al., 1996)"
"All these documented effects are due to the clinoptilolite capacity to adsorb harmful substances in the gastrointestinal tract that are not confined only to micotoxins and ammonia but include heavy metals and organic compounds as well."
"The results published thus far show that clinoptilolite does not affect the homeostasis of trace elements and micronutrients, but acts rather selectively on heavy-metals and toxicants. For instance, clinoptilolite-treated dairy goats showed no changes in serum concentrations of fat-soluble vitamins, macro-elements, and trace elements, or activities of hepatic enzymes. In addition, clinoptilolite supplementation improved milk fat percentage and milk hygiene (Katsoulos et al., 2009). No effects of clinoptilolite on physiological mineral levels have been observed in cows (Katsoulos et al., 2005a; Valpotić et al., 2017)."
"shown a positive effect of clinoptilolite supplementation on lowering the total lipid count and LDL (low density lipoproteins), which may also be indirectly correlated with its general antioxidative effect (Cutovic et al., 2017)."
There's many more positive studies shown.
I actually have the expensive bottles of TRS I need to use it!
@jessica2 I think it depends on the particle size and type of the charcoal on what metals it can adsorb. But yes that review was just on sorbents as a whole. Lots of literature out there on this! But when I try googling activated charcoal not much comes up. I guess we need to look up the right terms.
Quote from Frank on February 7, 2024, 6:09 pmQuote from Janelle525 on February 7, 2024, 5:21 pmCharcoal extends lifespan of old rats:
"The effect of repeated courses of enter0sorption upon the mean and maximal lifespan
and some functional and metabolic indices was determined in 28-month-old Wistar rats. Significant increase of mean and maximal lifespan of old rats was noted at certain regimens of enterosorption. The experimental animals demonstrated less marked age-related structural and ultrastructural changes in the liver, kidneys, myocardium, intestines, pancreas, as compared with
control animals. Enterosorption leads to a reduction of pentobarbital-induced sleep, decrease of
content of cytochrome P-450, blood cholesterol and triglycerides, cardiac and cerebral tissue
cholesterol, total lipids, liver cholesterol and triglycerides. Enterosorption was found to increase
the RNA and protein biosynthesis in the liver, kidneys and adrenals of old animals."Read study, not abstract. Math is wrong, no reported variance, not all results reported!
Control age mean (at 50%, 80%, 100% mortality):
937, 972, 993 days.
Carbon Group 2 age mean (at 50%, 80%, 100% mortality):
977, 1023, 1055 days.
Group 2 divided by Control in percent is:
104%, 105%, 106%
So Group 2 carbon lived ~5% longer (on average but no measure of variance reported). Very small difference. But they say 47%, 41%, and 44% longer? How?!
They say Carbon Group 3 did worse but don't report number days, only percent. No numbers report or mention at all for Carbon Group 4! Did they all die?
Study is on "old animals". Maybe carbon help when body not work good anymore but harm young healthy animal.
Nobody read studies carefully...
Yeah I tried reading it! Old studies are terrible, they don't give all the info.
Quote from David on February 8, 2024, 4:12 amWhy did the all rats in this French 1945 study die within 125 days?
The life-span of laboratory rats in captivity is at least 2 years (730 days), see attached table with life development stage for rats taken from this 2021 paper called:
"The laboratory rat: Age and body weight matter"
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564917/125 /730 = 17 % of some average excpected life span in captivity (this was the rats the lived the longest without any intervention).
How come?
-Certainly some research scientists shouldn't have pets.
No rats die in 1945 on "Vitamin A fortified diet", only die when no/low Vitamin A diet. I already summarize for everyone, very clear. Read again...closely.
Quote from Janelle525 on February 8, 2024, 7:51 amQuote from Frank on February 7, 2024, 6:09 pmQuote from Janelle525 on February 7, 2024, 5:21 pmCharcoal extends lifespan of old rats:
"The effect of repeated courses of enter0sorption upon the mean and maximal lifespan
and some functional and metabolic indices was determined in 28-month-old Wistar rats. Significant increase of mean and maximal lifespan of old rats was noted at certain regimens of enterosorption. The experimental animals demonstrated less marked age-related structural and ultrastructural changes in the liver, kidneys, myocardium, intestines, pancreas, as compared with
control animals. Enterosorption leads to a reduction of pentobarbital-induced sleep, decrease of
content of cytochrome P-450, blood cholesterol and triglycerides, cardiac and cerebral tissue
cholesterol, total lipids, liver cholesterol and triglycerides. Enterosorption was found to increase
the RNA and protein biosynthesis in the liver, kidneys and adrenals of old animals."Read study, not abstract. Math is wrong, no reported variance, not all results reported!
Control age mean (at 50%, 80%, 100% mortality):
937, 972, 993 days.
Carbon Group 2 age mean (at 50%, 80%, 100% mortality):
977, 1023, 1055 days.
Group 2 divided by Control in percent is:
104%, 105%, 106%
So Group 2 carbon lived ~5% longer (on average but no measure of variance reported). Very small difference. But they say 47%, 41%, and 44% longer? How?!
They say Carbon Group 3 did worse but don't report number days, only percent. No numbers report or mention at all for Carbon Group 4! Did they all die?
Study is on "old animals". Maybe carbon help when body not work good anymore but harm young healthy animal.
Nobody read studies carefully...
Yeah I tried reading it! Old studies are terrible, they don't give all the info.
So you know you use bad study to defend charcoal? You bias and sell bias, not nice.
Many old studies great, many new studies bad. If you read study closely, you know which good and which bad, and which bias.
USSR carbon study bias: "We also hoped that quite effective could be a longterm sorption of toxic agents, rather than a shortterm course..."
Good science not "hope" anything. Good science observe and report, no bias.
Quote from Jessica2 on February 8, 2024, 7:59 am@janelle525 Zeolite is a fascinating substance. I'm not sure I would ingest it, but maybe. I'd have to look at it again. Interestingly when I was looking up stuff on activated charcoal, bentonite clay was coming up too. Apparently bentonite clay has been shown in the literature to get rid of vitamin A for anyone who's interested. I think there was a poultry study in the 50s on it.
I'm not sure I would ingest it although I know there is a history of ingesting clay in certain cultures and times. Perhaps I would. I thought I would mention it for those interested though to look up themselves.
Interesting! I have taken clay in small doses to try and help with my chronic vomiting. I have also seen good effects of using it topically. I heard it has a lot of aluminum, so maybe topically is better. I think that pesto bismol has clay in it, so maybe clay might be useful for upset due to too much of something that is toxic? I once had food poisoning and another guy who ate the same food also got it too and he took pepto bismol and I took antibiotics and he got better faster. I've read that trad people say that water from unglazed clay pots is very healthful. But now we are talking about microscopic amounts. But maybe that is good over the long term. Helpful enough without poisoning you in some other way.
Quote from Frank on February 8, 2024, 12:05 pmQuote from Janelle525 on February 8, 2024, 7:51 amQuote from Frank on February 7, 2024, 6:09 pmQuote from Janelle525 on February 7, 2024, 5:21 pmCharcoal extends lifespan of old rats:
"The effect of repeated courses of enter0sorption upon the mean and maximal lifespan
and some functional and metabolic indices was determined in 28-month-old Wistar rats. Significant increase of mean and maximal lifespan of old rats was noted at certain regimens of enterosorption. The experimental animals demonstrated less marked age-related structural and ultrastructural changes in the liver, kidneys, myocardium, intestines, pancreas, as compared with
control animals. Enterosorption leads to a reduction of pentobarbital-induced sleep, decrease of
content of cytochrome P-450, blood cholesterol and triglycerides, cardiac and cerebral tissue
cholesterol, total lipids, liver cholesterol and triglycerides. Enterosorption was found to increase
the RNA and protein biosynthesis in the liver, kidneys and adrenals of old animals."Read study, not abstract. Math is wrong, no reported variance, not all results reported!
Control age mean (at 50%, 80%, 100% mortality):
937, 972, 993 days.
Carbon Group 2 age mean (at 50%, 80%, 100% mortality):
977, 1023, 1055 days.
Group 2 divided by Control in percent is:
104%, 105%, 106%
So Group 2 carbon lived ~5% longer (on average but no measure of variance reported). Very small difference. But they say 47%, 41%, and 44% longer? How?!
They say Carbon Group 3 did worse but don't report number days, only percent. No numbers report or mention at all for Carbon Group 4! Did they all die?
Study is on "old animals". Maybe carbon help when body not work good anymore but harm young healthy animal.
Nobody read studies carefully...
Yeah I tried reading it! Old studies are terrible, they don't give all the info.
So you know you use bad study to defend charcoal? You bias and sell bias, not nice.
Many old studies great, many new studies bad. If you read study closely, you know which good and which bad, and which bias.
USSR carbon study bias: "We also hoped that quite effective could be a longterm sorption of toxic agents, rather than a shortterm course..."
Good science not "hope" anything. Good science observe and report, no bias.
Actually I made a mistake, I used a study Dr Ray Peat is known for quoting on the benefits of charcoal. I Finally read it and ya know it doesn't exactly say what he thinks it says. But doesn't negate the use of charcoal either.
Quote from tim on November 1, 2023, 3:05 pmI think Frank is Gadzooks. Regardless, it's a troll account.
Quote from tim on November 1, 2023, 3:37 pmFor those that don't know Frank is the ghost of a boy Donnie killed in the movie Donnie Darko. He haunts Donnie.
The username frank-2 is a mimic of mine.
Two quotes from from tim in this thread from 2023:
https://ggenereux.blog/discussion/topic/paul-saladino-pushing-vita-hard/?part=6
Don't feed the trolls.
Is that Aussie talk, LOL? what is "a mimic of mine"? Real question. Does he mean that Frank just trolls him on every turn?
I thought "mimic" meant someone who copies you.
Quote from David on February 8, 2024, 11:41 pmQuote from tim on November 1, 2023, 3:05 pmI think Frank is Gadzooks. Regardless, it's a troll account.
Quote from tim on November 1, 2023, 3:37 pmFor those that don't know Frank is the ghost of a boy Donnie killed in the movie Donnie Darko. He haunts Donnie.
The username frank-2 is a mimic of mine.
Two quotes from from tim in this thread from 2023:
https://ggenereux.blog/discussion/topic/paul-saladino-pushing-vita-hard/?part=6Don't feed the trolls.
Sorry, I forget this Vitamin poison A safe place where you decide "facts" yourself. I try harder to remember rules now.
1945 study does say all rats die. Vitamin A make rats die faster. Carbon make rats die slower.
Did I get "facts" right?