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Antidote?
When I started my 'healthier' eating over 23 years ago I was definitely looking at the GLA factor and eating borage leaves from my garden (in smoothies cause tastes awful), drinking blackcurrant kvass and eating hemp seeds for a period of time. Then after a period of stress 7 years later I did indeed get psoriasis. I then went on a high fat diet and got rid of the psoriasis. I thought it was the taurine that helped but it may have been the fats in lamb hearts and other organ meats that did the trick.
Loss of delta-6-desaturase activity is hypothesised as a key factor in aging. Diabetes, alcohol and radiation inhibit D6D activity too. cAMP levels fall as we age perhaps D6D impairment also affects cAMP involved in psoriasis. D6D impairment possibly being the abnormal function hypothesised to cause psoriasis. Could it be aldehydes do something similar ? D6D is also affected by severity of liver health too.
Up to the point that D6D enzyme starts working better then there may be an increased need for fats which some on the low fat approach may be sabotaging inadvertently. It would seem that replenishing choline, biotin, inositol and betaine helps liver health and improves fat absorption and digestion and there may be some connection to improving D6D at that point or before simply by reducing aldehydes. I havent found a direct link yet though. When I started eating more eggs I also switched from brazil nuts to sunflower seeds and they may be very beneficial in some way also. I ate a few cashew nuts and occasionally peanuts as well. I think a more moderate fat amount from these sources might have been preferable. Avoiding lamb might have been another mistake I made.
D6D and aging. https://www.sciencedirect.com/science/article/abs/pii/0306987781900645?via%3Dihub
@pattycake this is all really interesting. And thank you for saying that. My reaction to grass fed beef fat is consistent with the other symptoms I attribute to VA. The primary ones are headaches, facial inflammation, and anxiety, but there are multiple others that play a smaller role.
@pattycake will do. I added in scallops on Tuesday, and the heart palpitations resolved that day, and the dry scaly rash was mostly gone within a few days. I took them out for one day yesterday, and the heart palpitations came back. Of course, it could have been anything in the scallops leading to these effects, but EPA/DHA seem most likely. I am planning to swap walnuts for them pretty soon and will report back.
Quote from Jessica2 on April 9, 2023, 4:08 amThis essential fatty acid factsheet lists frequent urination as a symptom of essential fatty acid deficiency. I remember while in the throes of CLO and recovery, I was getting up at least 3 times a night to go. It was worse than during pregnancy.
Note that poor night vision and sensitivity to light are also symptoms of EFA deficiency:
https://www.fabresearch.org/uploads/itemUploads/6698/FACTSHEET%20002-PFADS%202003-11.pdf
Ironically, Someone on the LYL network posted yesterday about her daughter's bladder urgency and urinary incontinence issues that have progressively gotten worse over the past two years, in spite of being on the LYL program since 2019. (my daughter has recently developed the same issue, so this caught my attention.) So I thought, what the heck, I will do a search for PUFA's and urinary incontinence. There was a survey study (I know, not the best, correlation does not equal causation etc) but the conclusion was "the ratio of saturated fat intake to polyunsaturated fat intake was positively associated with UI (highest quintile vs. lowest: adjusted odds ratio = 2.48, 95% confidence interval: 1.22, 5.06) and was strongly associated with severity (Ptrend < 0.0001). Conclusion: In this population-based cross-sectional study, women who had a higher SFA:PUFA ratio or higher total daily calorie intake had significantly greater odds of urinary incontinence. No associations were observed for total fat, carbohydrate, or protein intake. (My daughter started taking some oils about a week ago, so I will be curious to see if she sees improvements.)
I have only skimmed the article, but here it is, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877472/
https://www.gbhealthwatch.com/Science-Omega3-Omega6.php
Researchers found that olive oil consumption promotes healthy gut microbiota and hinders the development of gut pathogens that impair immune function. Researchers have found a positive correlation between following the Mediterranean diet and decreased prevalence of autoimmune diseases.
I always felt good when using olive oil and avocado oil; that was before I started eating a bunch of cheese, butter, cream, etc with keto/carnivore. I may try olive oil and see how that goes. I'm going with the California Olive Ranch as that has a paper trail.
Uploaded files:
https://www.nature.com/articles/s41569-018-0078-9
In 2015, the group reported that a natural product found in cold-pressed extra-virgin olive oil, 3,3-dimethyl-1-butanol (DMB), inhibits microbiotal choline TMA lyase activity, leading to reductions in plasma TMAO level and in atherosclerotic lesion development in mice.
https://www.sciencedirect.com/science/article/abs/pii/S0899900718301023
In relation to diet, it has been proven that olive oil can have a beneficial effect. Several studies conclude that its intake can significantly reduce the deposit of fat in the liver. In a recent study, olive oil was administered in the diet to 32 patients with fatty liver for 12 weeks and compared with 34 others who took sunflower oil. In those patients in whom their diet included olive oil, it was found a higher decrease in liver fat and in the percentage of body fat than in those who received sunflower oil. Other studies have shown a similar effect when comparing olive oil with other types of oil (such as soy and safflower oil).
My problem with these kinds of things is... I really want to try the 4:1 omega six to omega three ratio. But do I test beforehand, and after? As some sort of proof for myself, you guys? That'd be the best of course. But it's also €80 per test, add in possible vitamin A tests (not doing these) for proof and it adds up quickly.
I did just order the first test, everytime I was psoriasis free I also ate 1-3 tablespoons of ground flax seed per day. Let's see what's what with my lipids.
Looking for a nice way to eat the oil and ground flax seeds. Maybe I'll just buy the expensive hemp oil that's close to the perfect 4:1 ratio? I used to eat the ground flax seeds in yogurt, and I kind of quit dairy because vA scaremongering. I'd love something similar but low A style. Or would it be good enough to just reheat my beans and add the omega 6 oil and ground flax over it? Let's say the beans are still 80C, would that be too hot? Maybe cold sushi rice would work?
Edit:
Also a bit worried about the phytoestrogens in freshly ground flax seeds. Flaxseed oil doesn't have this, but all oils are practically rancid. I hope the hemp oil holds a bit better? I can find cold pressed organic. Now let's hope it isn't rancid.