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Copper and zinc metabolism
Quote from
tim on June 12, 2021, 3:28 am
When I try very hard lower my copper intake I still get RDA lol
This is so true, it's very hard to eat a low copper diet.
I think it's likely that B vitamin deficiencies, particularly riboflavin deficiency play a major role in poor regulation of iron and copper in the body. Riboflavin deficiency affects well over half the population too, it's more common even than iodine and vitamin D deficiency. Riboflavin is needed at multiple steps in vitamin A metabolism and it's needed for making liver iron stores bio-available.
@jiri
When you were trying to lower copper levels how did sugar consumption affect that given that excess fructose is thought to cause copper deficiency?
When I try very hard lower my copper intake I still get RDA lol
This is so true, it's very hard to eat a low copper diet.
I think it's likely that B vitamin deficiencies, particularly riboflavin deficiency play a major role in poor regulation of iron and copper in the body. Riboflavin deficiency affects well over half the population too, it's more common even than iodine and vitamin D deficiency. Riboflavin is needed at multiple steps in vitamin A metabolism and it's needed for making liver iron stores bio-available.
@jiri
When you were trying to lower copper levels how did sugar consumption affect that given that excess fructose is thought to cause copper deficiency?
Quote from
Jiří on June 12, 2021, 3:46 am
@tim-2 I don't know my low copper diet is rice and meat heh. Not so much sugar with fructose. Fructose is burden for the liver for sure. Estrogen, iron, copper, fructose, vit A etc. All that in excess gives liver very hard time..
@tim-2 I don't know my low copper diet is rice and meat heh. Not so much sugar with fructose. Fructose is burden for the liver for sure. Estrogen, iron, copper, fructose, vit A etc. All that in excess gives liver very hard time..
tim has reacted to this post.
Quote from
Jiří on June 12, 2021, 4:21 am
@jiri
What copper antagonists and liver/adrenal support would you recommend for copper toxicity?
From what I've seen, supplementing with molybdenum and eating whole food Vitamin C is good to do, in addition to getting a higher zinc:copper ratio?
Did eating copper make you feel kind of jittery/shaky when you were toxic with it? I recently tried supplementing with a tiny amount (0.25mg of copper glycinate) and I felt pretty strange several hours afterward. The copper seemed like the only thing that would explain the sensation.
I get stimulated by eating copper. Which I can even measure with heart rate and blood pressure. Most of the time my BP is normal or low under 120. When my serum free copper goes up(copper dump) I will get high BP 140+.. That's why vegans say they feel good. They are eating like 5-10mg a day no problem maybe even more.. But to me it's not pleasant energy. It's exactly like you say this jittery, anxious type of energy.. Copper antagonists vit C, zinc, molybdenum are the strongest. But the problem is when you have toxicity most of the time you don't have high serum free copper. If you do like I did and you know it by blood test you can increase vit C, zinc, molybdenum to lower this very damaging high free copper, but most of the time people toxic in copper have low serum copper and you don't wat to lower it even more and end up with some serious copper deficiency issues like even aneurysm... I had a lot of vein issues from it. So I have plenty of spider veins like some 80 yo lady.. I'ts better to not eat high copper foods and like you said keeping good zinc:copper ratio. Which is easily done by simply eating only food with good zinc:copper ratio for example I was eating buckwheat a lot for years.. That's why I for example stopped eating buckwheat and stared with oats. Much lower copper and higher zinc.. and taking copper antagonists only low dose like vit C no more than 500mg a day and minerals not taking daily. I take like 15mg of zinc every other day and 400mcg of molybdenum maybe once a week.. I think basically everyone is deficient in molybdenum. Sme with chromium.. Hair test is great way to know your micro mineral status.. It's the only way for now actually..
@jiri
What copper antagonists and liver/adrenal support would you recommend for copper toxicity?
From what I've seen, supplementing with molybdenum and eating whole food Vitamin C is good to do, in addition to getting a higher zinc:copper ratio?
Did eating copper make you feel kind of jittery/shaky when you were toxic with it? I recently tried supplementing with a tiny amount (0.25mg of copper glycinate) and I felt pretty strange several hours afterward. The copper seemed like the only thing that would explain the sensation.
I get stimulated by eating copper. Which I can even measure with heart rate and blood pressure. Most of the time my BP is normal or low under 120. When my serum free copper goes up(copper dump) I will get high BP 140+.. That's why vegans say they feel good. They are eating like 5-10mg a day no problem maybe even more.. But to me it's not pleasant energy. It's exactly like you say this jittery, anxious type of energy.. Copper antagonists vit C, zinc, molybdenum are the strongest. But the problem is when you have toxicity most of the time you don't have high serum free copper. If you do like I did and you know it by blood test you can increase vit C, zinc, molybdenum to lower this very damaging high free copper, but most of the time people toxic in copper have low serum copper and you don't wat to lower it even more and end up with some serious copper deficiency issues like even aneurysm... I had a lot of vein issues from it. So I have plenty of spider veins like some 80 yo lady.. I'ts better to not eat high copper foods and like you said keeping good zinc:copper ratio. Which is easily done by simply eating only food with good zinc:copper ratio for example I was eating buckwheat a lot for years.. That's why I for example stopped eating buckwheat and stared with oats. Much lower copper and higher zinc.. and taking copper antagonists only low dose like vit C no more than 500mg a day and minerals not taking daily. I take like 15mg of zinc every other day and 400mcg of molybdenum maybe once a week.. I think basically everyone is deficient in molybdenum. Sme with chromium.. Hair test is great way to know your micro mineral status.. It's the only way for now actually..
There is no such a thing as [well defined state of] vit D deficiency - the active metabolite calcitriol depends on the free part of D25 which is independent on the lab-measured D25(i.e. bound to vitamin D binding protein aka DBP)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976473/
Specifically, it is unbound, ‘free’ 25OHD that drives many of the non-classical actions of vitamin D.
...
Based on recent studies, it is possible that free or bioavailable 25OHD will provide a more meaningful marker of vitamin D function. For example, an individual with low serum 25OHD according to current parameters (less than 50 nM 25OHD), might nevertheless have adequate levels of free 25OHD
Trying to recover health by matching the values of vitamins/minerals to those in a healthy body is a well known fallacy - sometimes it leads to the temporal state of feeling better, but almost never to the state of being better.
There is no such a thing as [well defined state of] vit D deficiency - the active metabolite calcitriol depends on the free part of D25 which is independent on the lab-measured D25(i.e. bound to vitamin D binding protein aka DBP)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976473/
Specifically, it is unbound, ‘free’ 25OHD that drives many of the non-classical actions of vitamin D.
...
Based on recent studies, it is possible that free or bioavailable 25OHD will provide a more meaningful marker of vitamin D function. For example, an individual with low serum 25OHD according to current parameters (less than 50 nM 25OHD), might nevertheless have adequate levels of free 25OHD
Trying to recover health by matching the values of vitamins/minerals to those in a healthy body is a well known fallacy - sometimes it leads to the temporal state of feeling better, but almost never to the state of being better.
Jenny and Retinoicon have reacted to this post.
Quote from
tim on June 12, 2021, 8:04 am
@rockarolla
It's true that there is debate over the normal range for calcidiol and to make it more complicated there is evidence that genetic differences mean that normal ranges vary on an individual basis however the effects of vitamin D deficiency are clearly established.
Trying to recover health by matching the values of vitamins/minerals to those in a healthy body is a well known fallacy - sometimes it leads to the temporal state of feeling better, but almost never to the state of being better.
It's just about identifying the cause.
If someone is deficient or toxic in a nutrient because of deficiency or excess in the diet of course it's going to help... when it comes to vitamin A restoring normal serum/liver levels has enormous health benefits.
@rockarolla
It's true that there is debate over the normal range for calcidiol and to make it more complicated there is evidence that genetic differences mean that normal ranges vary on an individual basis however the effects of vitamin D deficiency are clearly established.
Trying to recover health by matching the values of vitamins/minerals to those in a healthy body is a well known fallacy - sometimes it leads to the temporal state of feeling better, but almost never to the state of being better.
It's just about identifying the cause.
If someone is deficient or toxic in a nutrient because of deficiency or excess in the diet of course it's going to help... when it comes to vitamin A restoring normal serum/liver levels has enormous health benefits.
Quote from
lil chick on June 14, 2021, 1:16 pm
Can anyone on this thread tell me why I just had an epic-ally bad reaction to two days of 1/2 dose of zinc supp? accepting guesses!
Can anyone on this thread tell me why I just had an epic-ally bad reaction to two days of 1/2 dose of zinc supp? accepting guesses!
Quote from
Jiří on June 14, 2021, 1:30 pm
Quote from
lil chick on June 14, 2021, 1:16 pm
Can anyone on this thread tell me why I just had an epic-ally bad reaction to two days of 1/2 dose of zinc supp? accepting guesses!
how many mg a day it was and what is bad reaction?
Quote from
lil chick on June 14, 2021, 1:16 pm
Can anyone on this thread tell me why I just had an epic-ally bad reaction to two days of 1/2 dose of zinc supp? accepting guesses!
how many mg a day it was and what is bad reaction?
lil chick has reacted to this post.
Quote from
lil chick on June 14, 2021, 1:16 pm
Can anyone on this thread tell me why I just had an epic-ally bad reaction to two days of 1/2 dose of zinc supp? accepting guesses!
Probably because you are zinc-deficient. I have no response to zinc since eating meat based diet, but high brain fog from either nuts or direct copper supplements, so I must be copper-deficient instead. 🙂 😀
Quote from
lil chick on June 14, 2021, 1:16 pm
Can anyone on this thread tell me why I just had an epic-ally bad reaction to two days of 1/2 dose of zinc supp? accepting guesses!
Probably because you are zinc-deficient. I have no response to zinc since eating meat based diet, but high brain fog from either nuts or direct copper supplements, so I must be copper-deficient instead. 🙂 😀
lil chick has reacted to this post.
Quote from
lil chick on June 14, 2021, 2:15 pm
Hi Guys, @jiri, @rockarolla I took half a pill for two days (which would make it about 25mg each, as the pills are 50 mg). I literally felt my stomach cramp up when the pill hit the stomach at breakfast this morning. Then it worked it's way through to explosive runs and cramps.
Hi Guys, @jiri, @rockarolla I took half a pill for two days (which would make it about 25mg each, as the pills are 50 mg). I literally felt my stomach cramp up when the pill hit the stomach at breakfast this morning. Then it worked it's way through to explosive runs and cramps.
Quote from
lil chick on June 14, 2021, 2:18 pm
I took the pills thinking that my worsening tinitus and night blindness might be helped.
I took the pills thinking that my worsening tinitus and night blindness might be helped.
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