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Copper issues with Vitamin A toxicity
Thanks! Should I test for Wilson decease?
Hi @jiri
While I'm waiting for my Wilson's decease test results, I wanted to ask you one more question - if my liver fails to make proper amounts of caruloplasmin, would it be possible it also fails to produce enough retinol-binding protein, and thus make lots of vitamin A in my blood unbound, i.e. more toxic? Is there such a thing as free retinol? My serum retinol and b-carotene are within range, however, I don't feel good after eating either. However, if my liver was super toxic with vitamin A, I guess it would mean that I'd feel awful all the time, which is not the case. I was thinking there might be some "threshold" of free vitamin A or copper in my blood, which I exceed by eating food containing them, going from feeling okayish to lousy.
@viktor yes RPB is in the same category like ceruloplasmin. I don't think you have wilsons disease. You would already know that something is really wrong a long time ago... Don't complicate things so much. Just be nice to your liver. Don't eat a lot of fructose, fat, retinol, copper and give the liver some time to recover.. For that you need good amount of protein, B vitamins (especially choline. I take choline bitartrate with inositole 250mg 3x a day) and some minerals like molybdenum, zinc, selenium...
Hi @viktor
I have never posted here before but I have followed this blog for a while. Your post really got my attention since I was in a very similar situation as you. I don't think I was very high in vitamin a though, but I probably had some levels of over saturation. Anyways before I actually started the low vitamin a diet I actually had all the symptoms you described here and I'm quite sure they are because oxalate toxicity, I didn't realize about it before. I would feel quite sick after eating ( dizzy, vision issues, hot flashes, super sleepy, sometimes headaches, shoulder and back pain) and as you I was eating a lot of buckwheat, I started quitting all my foods one by one because I had the idea they were making me sick, ended up eating only white bread, white rice, coconut milk (it was fortified with vitamin a) , meats, some iceberg lettuce and maybe some fruits here and there. As you can see the diet I took that made me feel way better in a matter of days was probably lower in vitamin a since I was eating dairy before and some high vitamin A veggies but it was also way lower in oxalates. I didn't know this back then I thought I was perimenopausal having estrogen issues and that maybe too much fiber was lowering my estrogen levels, lab tests didn't shed any light into my issues.
Anyways I was feeling way better for two years but sometimes the issues would come back when I eat some high oxalate foods like dark chocolate, spinach salads so I wasn't all satisfied and ran into this blog and started a low vitamin a diet. It was good at the beginning but because I started adding some other foods like black beans, oats then symptoms started back again.
I finally now found info on oxalates and I have been eating low oxalates for a while but as I progressed in low vitamin A diet hot flashes started returning and some vision issues, I was very very puzzled by this, since I'm not eating much oxalates at all and found references to the article bellow where it links vitamin a deficiency to endogenous production of oxalates, not good 🙁 ). So I think this is where I'm now and I'm going to try to get my vitamin a increased again but while keeping my dietary oxalates to a minimum for the time being, I will never eat dairy again though.
Anyways this is my case but you are probably in the early stages where really you are just eating too much oxalates and your body is saturated with it. Buckwheat was my worse enemy. I guess this is a warning if you get too low in vitamin A you might get other problems down the road,
https://www.jstage.jst.go.jp/article/jcbn1986/11/3/11_3_205/_pdf