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Lactoferrin
Quote from r on February 2, 2024, 4:11 amQuote from Jessica2 on February 2, 2024, 3:55 am@r-2 No, Smith is NOT advocating for eating eggs now, he might be more against them than he was a year ago, though he has flipped on niacin.
Yes the pubmed issue is one I've recognized as well. We are supposed to believe the studies that show negative outcomes about vitamin A, but we aren't to believe any of the other ones except the ones he handpicks and presents as backups to his opinions? You literally could present PubMed studies to back up any opinion that you have. For instance the egg studies that Smith often quotes are in large part epidemiological and rely on food questionnaires which are widely and notoriously the most unreliable studies you could have on the subject. Yet he presents them as gospel truth and proof of the fact that eggs are "poison".
He ignores a whole large body of evidence that choline is hepatoprotective and prevents fatty liver in favor of epidemiological studies saying the opposite by studying forms of choline that aren't present in eggs and relying on patient recall of egg intake. My favorites were the ones that studied patients in "group homes"; assisted living and nursing facilities, so we're talking old sick people already that supposedly showed negative outcomes with egg intake. Really jokes of studies. I've posted many studies showing the exact opposite in my bile and choline threads.
One way to not get in trouble is to not guide your health journey based on PubMed , rather your own gut feeling and how to react . Often times I have gotten in trouble because I read too much unnecessary and then ended up believing in something which really messed up my health again . Old saying goes well . "if it aint broken , no need to fix it " .
Partly I believe why grant has done well is because he stayed away from "PubMed" . If bean , beef and rice works well he didnt plan to tinker with it .
I dont read much these days , instead I read my body
Quote from Jessica2 on February 2, 2024, 3:55 am@r-2 No, Smith is NOT advocating for eating eggs now, he might be more against them than he was a year ago, though he has flipped on niacin.
Yes the pubmed issue is one I've recognized as well. We are supposed to believe the studies that show negative outcomes about vitamin A, but we aren't to believe any of the other ones except the ones he handpicks and presents as backups to his opinions? You literally could present PubMed studies to back up any opinion that you have. For instance the egg studies that Smith often quotes are in large part epidemiological and rely on food questionnaires which are widely and notoriously the most unreliable studies you could have on the subject. Yet he presents them as gospel truth and proof of the fact that eggs are "poison".
He ignores a whole large body of evidence that choline is hepatoprotective and prevents fatty liver in favor of epidemiological studies saying the opposite by studying forms of choline that aren't present in eggs and relying on patient recall of egg intake. My favorites were the ones that studied patients in "group homes"; assisted living and nursing facilities, so we're talking old sick people already that supposedly showed negative outcomes with egg intake. Really jokes of studies. I've posted many studies showing the exact opposite in my bile and choline threads.
One way to not get in trouble is to not guide your health journey based on PubMed , rather your own gut feeling and how to react . Often times I have gotten in trouble because I read too much unnecessary and then ended up believing in something which really messed up my health again . Old saying goes well . "if it aint broken , no need to fix it " .
Partly I believe why grant has done well is because he stayed away from "PubMed" . If bean , beef and rice works well he didnt plan to tinker with it .
I dont read much these days , instead I read my body
Quote from lil chick on February 2, 2024, 9:42 amAnd you can't even go by "what makes you feel good". As I just posted, going off alcohol has brought back detox...
Studies!... , you guys are right! haha, not very much help (shaking my head).
And we can't even go entirely with tradition (just because a food is ubiquitous doesn't mean it is healthy) or even our gut feelings (we're going to have our addictions....)
Still and all, I do like to live this way lately: I fast between meals. When hungry, I eat what I'm in the mood for. After I eat it, I listen to see if there is some sort of lingering want. If so, I eat a little of that too.
We almost have to do the right thing just because we intuit that it is right.
I have this current interest in the speeches of Alan Watts on the channel Afterskool. I can't find the speech right now, but he talks about the difference between spotlight-focus and flood-light focus. Spotlight focus might be when you are thinking of one nutrient, say, vitamin C. Spot-light focus is very narrow and only good for little puzzles. A math problem or a crossword puzzle. Flood-light focus is for complicated things, like most of real life. For real life you need a higher realm of awareness that accesses everything you *know*, and maybe even beyond that. (!)
In a more scientific way, I think Dr. O'Mara's habit of evaluating whether people are, in the months after changes are made, losing their visceral fat--or NOT-- as being useful. It's important, I think, not to get too caught up in how you look and feel *daily*, though. But if, over the long term, a food keeps making you feel bad, that is something for the "flood-light focus" to take into account.
And you can't even go by "what makes you feel good". As I just posted, going off alcohol has brought back detox...
Studies!... , you guys are right! haha, not very much help (shaking my head).
And we can't even go entirely with tradition (just because a food is ubiquitous doesn't mean it is healthy) or even our gut feelings (we're going to have our addictions....)
Still and all, I do like to live this way lately: I fast between meals. When hungry, I eat what I'm in the mood for. After I eat it, I listen to see if there is some sort of lingering want. If so, I eat a little of that too.
We almost have to do the right thing just because we intuit that it is right.
I have this current interest in the speeches of Alan Watts on the channel Afterskool. I can't find the speech right now, but he talks about the difference between spotlight-focus and flood-light focus. Spotlight focus might be when you are thinking of one nutrient, say, vitamin C. Spot-light focus is very narrow and only good for little puzzles. A math problem or a crossword puzzle. Flood-light focus is for complicated things, like most of real life. For real life you need a higher realm of awareness that accesses everything you *know*, and maybe even beyond that. (!)
In a more scientific way, I think Dr. O'Mara's habit of evaluating whether people are, in the months after changes are made, losing their visceral fat--or NOT-- as being useful. It's important, I think, not to get too caught up in how you look and feel *daily*, though. But if, over the long term, a food keeps making you feel bad, that is something for the "flood-light focus" to take into account.
Quote from kularity on May 14, 2024, 5:58 amQuote from Orion on November 18, 2021, 3:41 pmQuote from Hermes on November 18, 2021, 2:57 pmHave you found a good night of sleep supplementing with lactoferrin?
@christian I will keep you updated here, want to see how this first week goes, last night was decent, did ~6hr stretch to 5:30am, woke then slept til 7:30am, wakings now usually only last about ~5mins. In the past wakings were jolts, wide awake, heart beating fast, almost impossible to fall back asleep quickly.
I have tried so many many many ideas/diets/supps/drugs that getting to low VA is the last thing I will ever try, I had given up and laughed when I discovered Grant's ideas, but after reading, said this is last attempt at some hypothesis. Least I feel more normal than for long time, and don't take any supplements to feel this way. These gut modifiers are the last supps I will attempt, I do think the gut will be tough to heal after accutane, like the last piece of the puzzle, clean liver and gut. In the end I just want to be free of ever having to know any of this last decade of health research! lol
I have been channeling all my positive vibes into my guitar, lots of growth there and always make time for friends on weekends
This hit me in the feels. The process of trying thing after thing yet not finding the right thing can really grind you down.
Whats the latest on you progress?
What Supplements worked? what type of diet worked?
Quote from Orion on November 18, 2021, 3:41 pmQuote from Hermes on November 18, 2021, 2:57 pmHave you found a good night of sleep supplementing with lactoferrin?
@christian I will keep you updated here, want to see how this first week goes, last night was decent, did ~6hr stretch to 5:30am, woke then slept til 7:30am, wakings now usually only last about ~5mins. In the past wakings were jolts, wide awake, heart beating fast, almost impossible to fall back asleep quickly.
I have tried so many many many ideas/diets/supps/drugs that getting to low VA is the last thing I will ever try, I had given up and laughed when I discovered Grant's ideas, but after reading, said this is last attempt at some hypothesis. Least I feel more normal than for long time, and don't take any supplements to feel this way. These gut modifiers are the last supps I will attempt, I do think the gut will be tough to heal after accutane, like the last piece of the puzzle, clean liver and gut. In the end I just want to be free of ever having to know any of this last decade of health research! lol
I have been channeling all my positive vibes into my guitar, lots of growth there and always make time for friends on weekends
This hit me in the feels. The process of trying thing after thing yet not finding the right thing can really grind you down.
Whats the latest on you progress?
What Supplements worked? what type of diet worked?
Quote from kularity on May 14, 2024, 6:00 amQuote from r on February 1, 2024, 11:59 pmQuote from Jiří on February 1, 2024, 11:48 pmWonder why Smith or his people no longer talk about lactoferrin? Not even one word about it even from Charlie on Ray Peat forum who basically transformed Ray peat Forum to low vit A diet forum hehe.. I also wonder when lactoferrin binds to iron what happens next with it. When it is floating in the blood with iron on the back can the body use that iron? Are there any research on that?
One thing I don't like about Smith is his typical American capitalistic mindset, i.e., 'Let's try to package things as gold and sell them.' After all, he is trying to turn Vitamin A detox into a business, and I understand he has to desperately make it look different from what we are doing here or even what Grant is doing. What all the experiments in diet, here and elsewhere, have revealed is that we can't rely on these nutritional studies. I have seen students in the university try to copy-paste anything from the internet to get their research papers published.
Well, if the same research paper that claimed Vitamin A as a necessary vitamin is what we are refuting here, meanwhile, Dr. Smith blatantly quotes headings from PubMed as if they are a word from God. Logically and rationally, we can juggle our way to prove anything with some Google searches and PubMed searches. For example, anyone with access to PubMed can prove a vegan diet is a cure for all diseases.
I'm starting to wonder if Smith doesn't think before 'claiming' facts from PubMed just to prove his point.
Moreover, over the past four years of following his research, he has changed his position on diets/supplements drastically. I mean, it's a good thing not to be stubborn about one belief, but if that's the case, then he shouldn't be so confident at the first instance of declaring something as a fact.
For example, once he was strictly against eggs, and he used to disparage consuming them. Now he is for the consumption of eggs, the same with supplements and various other foods.
A word of advice for Dr. Smith: it's okay to believe in something, but always add a caveat that you're not sure 100%
Yeah seems like there is a lot of speculation dressed up as truth in the low-vitamin-a community. makes it hard for someone new to figure out what to do except the obvious thing of reducing high vitamin-a food. Any advice for a newcomer?
Quote from r on February 1, 2024, 11:59 pmQuote from Jiří on February 1, 2024, 11:48 pmWonder why Smith or his people no longer talk about lactoferrin? Not even one word about it even from Charlie on Ray Peat forum who basically transformed Ray peat Forum to low vit A diet forum hehe.. I also wonder when lactoferrin binds to iron what happens next with it. When it is floating in the blood with iron on the back can the body use that iron? Are there any research on that?
One thing I don't like about Smith is his typical American capitalistic mindset, i.e., 'Let's try to package things as gold and sell them.' After all, he is trying to turn Vitamin A detox into a business, and I understand he has to desperately make it look different from what we are doing here or even what Grant is doing. What all the experiments in diet, here and elsewhere, have revealed is that we can't rely on these nutritional studies. I have seen students in the university try to copy-paste anything from the internet to get their research papers published.
Well, if the same research paper that claimed Vitamin A as a necessary vitamin is what we are refuting here, meanwhile, Dr. Smith blatantly quotes headings from PubMed as if they are a word from God. Logically and rationally, we can juggle our way to prove anything with some Google searches and PubMed searches. For example, anyone with access to PubMed can prove a vegan diet is a cure for all diseases.
I'm starting to wonder if Smith doesn't think before 'claiming' facts from PubMed just to prove his point.
Moreover, over the past four years of following his research, he has changed his position on diets/supplements drastically. I mean, it's a good thing not to be stubborn about one belief, but if that's the case, then he shouldn't be so confident at the first instance of declaring something as a fact.
For example, once he was strictly against eggs, and he used to disparage consuming them. Now he is for the consumption of eggs, the same with supplements and various other foods.
A word of advice for Dr. Smith: it's okay to believe in something, but always add a caveat that you're not sure 100%
Yeah seems like there is a lot of speculation dressed up as truth in the low-vitamin-a community. makes it hard for someone new to figure out what to do except the obvious thing of reducing high vitamin-a food. Any advice for a newcomer?
Quote from Orion on May 14, 2024, 8:53 am@kularity sticking with low VA and no supplements, except for some B5 daily. Progress slow, but has been steady, every time I try to mess with supplements progress halts. Been doing it for 5.5yrs
@kularity sticking with low VA and no supplements, except for some B5 daily. Progress slow, but has been steady, every time I try to mess with supplements progress halts. Been doing it for 5.5yrs
Quote from kularity on May 15, 2024, 8:26 amwhats the reasoning for B5?
I have seen some people talking about B1 but have missed the B5.
Yeah seems like all the supplements (fiber included) are speculative.
whats the reasoning for B5?
I have seen some people talking about B1 but have missed the B5.
Yeah seems like all the supplements (fiber included) are speculative.
Quote from To on February 27, 2025, 3:20 amHG7 protocol supposedly allow for consumption of much more lactoferrin without adverse effects
Alright it should be the end of week 1 for @charlieI made claims of benefits after one week. Would you describe what you have experienced so far?I am about a week in,. Only a bit of nausea every now and then. My eyes went through some kind of heavy detox, stuff poured out of them for about 5 days or so, it is finally slowing down. The whites of my eyes are much whiter now. The stuff was oozing out my eyes at such an incredible rate, it was a bear to get through because it burned too. I also got a stye. The amount of yellow and odd colored stuff that came out is almost unbelievable. I pushed through it and seem to be on the other side of that.
I have also been doing the protocol and sometimes using Lactoferrin in place of EGCG. I am taking 2 grams of Lactoferrin which is an incredible feat itself. I could barely handle a couple hundred milligrams of it before. But with this protocol much higher doses are tolerable. I am going to push up to 3 grams of Lactoferrin soon. I am also doing two of the protocols a day now with most of the protocols being with EGCG.
As far as benefits I am going to withhold sharing for now, but I see no reason to stop. From my personal observations this protocol seems to be moving a TON of metals out. I can smell the metals coming out of me.
Does this look promising from what experience I have with it so far? At this point in time I would cautiously say yes. But I am only a week in and want to see this further. I have family members chomping at the bit and wanting to start it up but I want to make sure it does what it is supposed to. The potential of this is truly mind blowing if it plays out the way most of us want it to.
HG7 protocol supposedly allow for consumption of much more lactoferrin without adverse effects
Alright it should be the end of week 1 for @charlieI made claims of benefits after one week. Would you describe what you have experienced so far?I am about a week in,. Only a bit of nausea every now and then. My eyes went through some kind of heavy detox, stuff poured out of them for about 5 days or so, it is finally slowing down. The whites of my eyes are much whiter now. The stuff was oozing out my eyes at such an incredible rate, it was a bear to get through because it burned too. I also got a stye. The amount of yellow and odd colored stuff that came out is almost unbelievable. I pushed through it and seem to be on the other side of that.
I have also been doing the protocol and sometimes using Lactoferrin in place of EGCG. I am taking 2 grams of Lactoferrin which is an incredible feat itself. I could barely handle a couple hundred milligrams of it before. But with this protocol much higher doses are tolerable. I am going to push up to 3 grams of Lactoferrin soon. I am also doing two of the protocols a day now with most of the protocols being with EGCG.
As far as benefits I am going to withhold sharing for now, but I see no reason to stop. From my personal observations this protocol seems to be moving a TON of metals out. I can smell the metals coming out of me.
Does this look promising from what experience I have with it so far? At this point in time I would cautiously say yes. But I am only a week in and want to see this further. I have family members chomping at the bit and wanting to start it up but I want to make sure it does what it is supposed to. The potential of this is truly mind blowing if it plays out the way most of us want it to.
Quote from Jiří on February 27, 2025, 4:52 am@to the guy that created HG7 or even Charlie the admin of the forum don't even understand the difference between lactoferrin and APOlactoferrin. In fact they don't even know that different forms exist.. They also don't know that lactoferrin can't chelate iron from the body. It just reduces free iron and keeps it from doing damage to the tissues..
@to the guy that created HG7 or even Charlie the admin of the forum don't even understand the difference between lactoferrin and APOlactoferrin. In fact they don't even know that different forms exist.. They also don't know that lactoferrin can't chelate iron from the body. It just reduces free iron and keeps it from doing damage to the tissues..
Quote from Pepe on December 10, 2025, 12:21 pmHi, I (accutane damaged) am new to the party – been lurking here for a while and just want to tell you what I know about metal chelation.
It is crucial when to take the metal chelator. I have been doing the Cutler Protocol with Alpha-Lipoic-Acid (ALA) and DMSA, with fantastic results for quite a while now. So ALA, DMSA and APOlactoferrin are all metal chelators. Metal chelators can increase or decrease the burden or certain metals. In the case of ALA it goes like this:
ALA on an empty stomach -> Mercury, Calcium and other metals leave the body.
ALA together with calcium -> Calcium absorption is increased.
I have tested it time and time again: If I take ALA together with calcium I get really bad headaches.
I hypothesize the same also applies to APOlactoferrin:
APOlactoferrin on empty stomach -> Iron, and other metals leave the body.
APOlactoferrin together with a meal with iron -> Iron absorption is increased, nothing will leave the body.
Hi, I (accutane damaged) am new to the party – been lurking here for a while and just want to tell you what I know about metal chelation.
It is crucial when to take the metal chelator. I have been doing the Cutler Protocol with Alpha-Lipoic-Acid (ALA) and DMSA, with fantastic results for quite a while now. So ALA, DMSA and APOlactoferrin are all metal chelators. Metal chelators can increase or decrease the burden or certain metals. In the case of ALA it goes like this:
ALA on an empty stomach -> Mercury, Calcium and other metals leave the body.
ALA together with calcium -> Calcium absorption is increased.
I have tested it time and time again: If I take ALA together with calcium I get really bad headaches.
I hypothesize the same also applies to APOlactoferrin:
APOlactoferrin on empty stomach -> Iron, and other metals leave the body.
APOlactoferrin together with a meal with iron -> Iron absorption is increased, nothing will leave the body.