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Rachel-2 my vitamin D

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Vitamin A toxicity reduces serum levels of vitamin D and antagonizes vitamin D activity.

See here from Garrett's blog: https://nutritionrestored.com/blog-forum/topic/natural-endogenous-vitamin-d-effects-are-antagonized-inhibited-interfered-with-by-poison-vitamin-a/

Other deficiencies such as zinc and esp. magnesium can impair proper functioning of vitamin D receptors. Bacterial infections such as mycoplasma can block vitamin D receptors.

There are many problems with vitamin D blood tests (just as with vitamin A). With vitamin D, the active molecule is 1,25 D but most tests only check the storage form 25(OH)D. People who seem to have "low" vitamin D are very rarely deficient in the active form. Next time you get a vitamin D test, ask them to also check your 1,25D levels. Also, there are several 25D molecules that the blood test doesn't check so it isn't even a comprehensive test for 25D.. Plus the current standard for what counts as low vitamin D has a problematic (and very recent) history and is arguably not evidence-based. And there is good evidence that longterm supplementation does more harm than good.
 
Oftentimes the symptoms of vitamin D deficiency are not due to an actual deficiency but rather a lack of other nutrients vitamin D needs to operate properly, especially magnesium and zinc. Sometimes bacterial infections can block the vitamin D receptors (so-called vitamin D receptor ligands such as mycoplasma I believe), which causes the symptoms of vitamin D deficiency but all that is needed is to take some concentrated rosemary to clear the receptors. 
 
Long story short: vitamin D supplements can do longterm harm. Better to get it naturally through sunshine or a UVB lamp. 
 
Here are more resources on vitamin D in support of the above statements: 
 
https://www.facebook.com/notes/garrett-smith/all-you-need-to-know-about-raising-vitamin-d-in-one-mega-post-please-share/1803607903016705/
 
https://mpkb.org/home/pathogenesis/vitamind/mechanisms#recent_research

https://mpkb.org/home/publications/marshall_bioessays_2008

https://mpkb.org/home/publications/albert_autoimmunity_reviews_2009

 
https://www.facebook.com/notes/garrett-smith/whos-been-saying-vit-d-supps-are-bad-dont-work-for-5-years-vitamin-d-supps-dont-/2013535978690562/

https://www.facebook.com/notes/garrett-smith/vitamin-d-testing-supplements-are-being-shown-to-be-a-fraud-and-low-carb-keto-ca/1954979161212911/

 
https://www.facebook.com/notes/garrett-smith/research-shows-that-vitamin-d-supplements-show-no-benefit-i-say-they-cause-many-/1951044064939754/
 
If you are on Facebook you should look at the posts by a guy named Jim Stephenson, Jr. 
 
tim and Rachel-2 in Colorado have reacted to this post.
timRachel-2 in Colorado

I am at 350 feet above sea level

@jiri

Oh man you ate a diet that low in fat for years? That could definitely cause liver and bile issues. Do you think that is a big thing that made you sick?

What do you think of the idea in bodybuilding that the body doesn't use much more than 30 grams of protein per meal for muscle growth?

I hate to jinx myself but I did not get "SAD" and hubs brought home something yucky from a trip to california (perhaps possibly even covid, although it was early in the game for that) and I didn't catch it from him, in fact, I didn't catch anything all winter last year.

@josh

My understanding is that 1,25(OH)2D lowers only when 25(OH)D is very low so do you not see much point in measuring 25(OH)D and see it as simply a background storage form of D?

Can you please elaborate on what differences you see between taking D3 and getting it from the sun?

Quote from tim on October 13, 2020, 8:08 am

@josh

My understanding is that 1,25(OH)2D lowers only when 25(OH)D is very low so do you not see much point in measuring 25(OH)D and see it as simply a background storage form of D?

Can you please elaborate on what differences you see between taking D3 and getting it from the sun?

@tim-2 Caveat: my understanding of vitamin D is almost entirely informed by Jim Stephenson, Jr. If you have Facebook, you should friend him and read through his posts. Tons of information. There is also a FB group he helped start secosteroid hormone D that has a lot of information, especially listed in their files. They believe that vitamin A is good for you (and even necessary for vitamin D receptor activation), which is something I disagree with but I know you are not entirely sold on that idea so you may find their perspective useful. 

If you don't have Facebook, I could try to dig up some of Jim's posts about D3 specifically. Let me know.

One of his recent posts was that although we tend to think of these as 3 different molecules (D3 D25 and D1,25), in fact there are many many different forms of each one, each with a different biological function. But if you're taking D3 as a supplement, you're only getting one form of the molecule, which itself is metabolized into one or a limited set of D25 molecules, etc. So you're much better off trying to get real D3 from the sun. But there are also dangers to D3 supplementation. 

Another thing he posts about a lot is how the mainstream recommendation for high 25D numbers is all wrong. 

Tim, what is your D25 number?

@tim-2 yes bodybuidling diet especially 10 years ago was high protein, moderate carbs, low fats. I was eating like I said lean meat, rice etc.. I had some "cheat meals" high in fats like once a week.. I think that "you can use only 40g per meal" is a myth because people when they killed animal they were eating a lot at once. What you don't eat will go bad or other animals will eat.. But I am 100% sure that for building muscles, speed up metabolism etc.. is eating every 3-4 hours the best for sure.. So you end up eating 30-50g of protein per meal. Some people try to claim that intermittent fasting is better, but I can tell you that nobody who has some result is doing that.. Everyone is eating constantly. Now I don't care about building more muscles so I do at least 12 hour fast during the night. I think it is ideal for most people..

@josh & @tim-2

About the "vitamin D from sun" vs supplemental D thing, I remember that Stephanie Seneff has written a few very detailed articles about it (dont have the links now but you'll find them easily through google).

Basically from what I remember she showed that the true form of the vitamin is made only through the skin from cholesterol and sulfate and something else. She told something like "if sulfate is deficient then taking vitamin D is actually dangerous but that cant happen through sun exposure" and she thinks that many people are sulfate deficient because of the high load of toxins everywhere.

I guess that supplementing vitamin D can also be dangerous is one if deficient in boron, magnesium or other cofactor while it won't happen through sun exposure as the body will hold on.

Josh and Rachel-2 in Colorado have reacted to this post.
JoshRachel-2 in Colorado

Guys pls when you say D3 supplementation can be dangerous. What about also saying in what dose? Don't tell me that doses like 1000-5000iu a day which you can also get from high fatty fish diet is dangerous as well.. If that was the case everyone would be dropping dead. Since almost everyone is taking at least multivitamin where are doses 1-5000iu.. + Almost all people who are "trying to be healthy" take much more like 10000 iu +...

Rachel-2 in Colorado has reacted to this post.
Rachel-2 in Colorado

@tim-2 Btw Grant is doing also very low fat diet. I don't know why. It is detrimental in a long term for sure... 

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