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Accutane Side effects - Spud Diet?

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The words "anti nutrient" should be banned from health sites. Nothing is black and white when it relates to our body.

All foods whether cooked or raw have drawbacks (carcinogens, pathogens...). Finding foods that are easy for your body to process is important.

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puddleduck
Quote from Guest on January 5, 2019, 7:18 pm

Please not the raw meat eater cult again and carcinogen please. People been eating cooked food for millenniums according to you everyone should have cancer. Raw food gurus are some of the most bizzare personalities complete wackos. Good luck eating raw ground beef I am sure that's very sanitary and practical because hey you are still alive.

If you have a reaction to a food simply drop it. White rice and white potatoes are generally tolerable by most people regardless of ethnicities. I find ridiculous this obsession over finding anti nutrients that by the way have different functions in your body so the villain status is very questionable.

Anyway, I hope that's not the direction this forum is going aka elimination of every suspect nutrient. I am sure there is a raw primal forum that caters to you.

I think that if anyone should be leaving it's you. You are rude and you're putting words in my mouth. Eat whatever you want but don't expect everyone to agree with you when you go around preaching that all nutrients are poison to the body. This forum is specifically about vitamin A and it's toxicity, not some fringe theory about how all vitamins are bad for you.

That's your position not mine. Reading comprehension isn't your thing.

Quote from ggenereux on January 5, 2019, 9:41 am

Hi Liz,

RE: I used accutane twice in my late teens/early twenties. I did not notice any side effects of it then. Does that still mean I may have permanently damaged my protein building function?

No, not necessarily so. There are a lot of variables.

A good reference site is: https://www.acne.org/accutane.html

See:

https://static.acne.org/ipb_uploads/monthly_2018_08/03-isotretinoin-has-serious-side-effects.jpg.019cce70addbe13c524fd54d2bcd67d3.jpg

And:

https://static.acne.org/ipb_uploads/monthly_2018_08/04-side-effects-of-accutane-isotretinoin.jpg.21ba5567cceda7b349fc87951b2b0f30.jpg

Note the warning:

Isotretinoin affects the entire body and can change not only the skin, but the entire body for the rest of a person’s life. This is why it is only approved for severe nodulocystic acne.

Of course, that has not at all deterred many doctors from prescribing it for mild acne too. Nor, does the now reported 1,700+ suicides attributed to Accutane use, and the 7,000+ cases of IBD.

But, I don’t think the damage is entirely permanent. Once retinoic acid has bound itself to the RNA/DNA, and depending on how severely the genes are damaged by it, the cells will be then be subsequently producing defective proteins and enzymes. That effect could last as long as those cells remain alive. So, maybe about for 7 – 10 years.

Thank you so much for replying Grant. I really appreciate the links, will check them out. I wonder though if the "dysfunction" will die with the cell or of it will follow along with the cell division first, and if so, how many cycles of cell division until this "dysfunction" will be "cut off" . Although, the body is pretty amazing at healing itself...

Quote from Guest on January 5, 2019, 5:30 pm
Quote from DareToBeNaive on January 5, 2019, 2:25 am
Quote from Guest on January 5, 2019, 1:28 am
Quote from DareToBeNaive on January 4, 2019, 4:31 am
Quote from ggenereux on January 3, 2019, 8:35 am

 

There was another person (also an Accutane victim) attempting to use a mostly potatoes diet. In the short-term, it appeared to be working for him. But, in the long run (~4 months) it gave him very negative results.  I really believe a good source of meat protein is essential.

There are two aspects to healing. Phase I is elimination of the toxic substances as best you can. Then, phase II is rebuilding damaged tissues and organ structures. That is going to take both a long time (think years), and the necessary amino acids ( protein building blocks).

You need to understand that this not just a simple poisoning. That is why it's routinely reported that Accutane can permanently damage the body. The reason is that with vit. A, and RA binds to RNA/DNA. With that your cells are now generating defective proteins and enzymes.  The defective proteins are still used as best the body can to maintain and repair itself.  So, you need to give your body the basic nutrients to repair itself correctly. I really don’t think potatoes alone are going to be adequate.

 

I think that eating lots of potatoes causes issues because potatoes are loaded with nutrients and that creates burden for our body. Best option imo is to process them heavily as in French fries. I first cut and boil them for 15-20 minutes and then fry.  And even with French fries if I eat more than a cup or so I have noticed heaviness from nutrition overload which can be felt after eating a lot of meat.

Nonsense. The reason why potatoes cause problems is because of the antinutrients, the solanine. And frying food is just about the single most unhealthy way to prepare food, it forms a ton of carcinogenic acrylamides. Frying barely affects the micronutrient content anyways so I don't see how it even would make sense in your theory.

 

I bet you you wont feel heavy if you eat your meat raw, especially not white meat.

Solanine is formed only if potatoes were exposed to sunlight which is noticeable by it's green coloration. And even if there is small amount it's usually just beneath the skin of the potato.

Don't sure about frying being unhealthy. I don't believe everything that science says. Fried potatoes are the most appetizing and I trust my senses. Raw meat is not appetizing at all so I don't think I should be eating it.

Wrong, solanine is in all potatoes. And if it gets green there is a ton of it. Most of it is in the skin, just like how most of the carotenoids in fruits are on the skin. If taste is all you care about maybe you should start eating icecream again, surely it must be good for you. And raw meat can be very appetizing, there are raw meat dishes in all cultures. Wait a minute, if cooked meat is appetizing, yet it makes you feel bad, doesn't that disprove your whole theory? Lmao. And no I don't watch Tufano.

I peel my potatoes . Skin actually does look very rough and unappetizing so another reason to trust our senses. I will experiment with butter and cream in the future exactly because I like the taste.

I don't feel bad after  cooked meat. If I consume let's says 300 g of red meat in one sitting i  just feel heaviness from satiation. Cooking meat actually enables us to extract more nutrition out of it with much less quantity.

Quote from ggenereux on January 4, 2019, 2:19 pm

Hi Alex,

I don't know what the mechanism is. But, please be aware that potatoes are also quite high in formaldehyde. So, eventually, potatoes will contribute to depleting alcohol dehydrogenase enzymes. That’s one of the enzymes is used to neutralize retinoic acid too.

Yes, there is some rebound type of effect going on too. It appears that the liver is releasing more of its stored retinal back in to circulation when people are in the first phase of this diet.

Best regards,

Grant

 

 

Thanks, so when it is being released back in to circulation, it is still necessary to get it out of circulation? I recall reading that somewhere otherwise it will still be in the the body and continue in circulation.. How does one do this? Zinc/ vitamin c etc?

 

Alex.

Has anyone else experimented with this diet?

Quote from ggenereux on January 5, 2019, 9:41 am

Hi Liz,

RE: I used accutane twice in my late teens/early twenties. I did not notice any side effects of it then. Does that still mean I may have permanently damaged my protein building function?

No, not necessarily so. There are a lot of variables.

A good reference site is: https://www.acne.org/accutane.html

See:

https://static.acne.org/ipb_uploads/monthly_2018_08/03-isotretinoin-has-serious-side-effects.jpg.019cce70addbe13c524fd54d2bcd67d3.jpg

And:

https://static.acne.org/ipb_uploads/monthly_2018_08/04-side-effects-of-accutane-isotretinoin.jpg.21ba5567cceda7b349fc87951b2b0f30.jpg

Note the warning:

Isotretinoin affects the entire body and can change not only the skin, but the entire body for the rest of a person’s life. This is why it is only approved for severe nodulocystic acne.

Of course, that has not at all deterred many doctors from prescribing it for mild acne too. Nor, does the now reported 1,700+ suicides attributed to Accutane use, and the 7,000+ cases of IBD.

But, I don’t think the damage is entirely permanent. Once retinoic acid has bound itself to the RNA/DNA, and depending on how severely the genes are damaged by it, the cells will be then be subsequently producing defective proteins and enzymes. That effect could last as long as those cells remain alive. So, maybe about for 7 – 10 years.

That's an extremely interesting point Grant.

My name is Lee, I have shared some correspondence with you before by email. I have taken Accutane and am doing all I can to recover from this.

I've been doing a low Vitamin A diet eating mostly beef, potatoes and rice for months now. I've had a breakthrough and found what might  be the missing link for me in the form of extended intermittent fasting.

Since doing daily 16/8 fasts and monthly 48 hour fasts the improvements in my fatigue, fibromyalgia type pain and sinus and eye issues has been dramatic.

I wonder if this could be because the longer fasts induce the natural process of autogphagy and perhaps speed up the regeneration of said defective proteins and enzymes you mention.

It's early days but I really believe the combination of low Vitamin A diet plus fasting will be the key to depleting my vitamin A levels and repairing the damage in the fastest possible time. It's already happening and i've tried everything including fecal microbial transplantation in my 5 years struggle post accutane.

Wishing everyone here the best of luck.

Regards,

Lee

 

 

 

 

Hello Lee,

Thanks for commenting and the update. That's really interesting to hear about your experience with fasting. Fasting is said to increase the production of HGH. So, I guess it makes sense that it could help. I'm glad to hear that things are working out for you.

Grant

Much appreciated Grant, thank you.

And thanks for making your work available to us all.

Regards,

Lee

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