Quote from
tim on January 25, 2022, 12:34 pm
Vitamin C status (more than intake) correlates with cardiovascular health. Elevated levels of retinoic acid deplete vitamin C due to collagen breakdown. Because humans are one of the few mammals that don't endogenously produce vitamin C I think that makes us more sensitive to excess vitamin A. Most senior citizens have Hypervitaminosis A, avoiding that into old age will probably confer longevity benefits. Everyone has a different ability to process vitamin A so while Hypervitaminosis A is correlated with dietary intake it's not a perfect correlation.
Vitamin C status (more than intake) correlates with cardiovascular health. Elevated levels of retinoic acid deplete vitamin C due to collagen breakdown. Because humans are one of the few mammals that don't endogenously produce vitamin C I think that makes us more sensitive to excess vitamin A. Most senior citizens have Hypervitaminosis A, avoiding that into old age will probably confer longevity benefits. Everyone has a different ability to process vitamin A so while Hypervitaminosis A is correlated with dietary intake it's not a perfect correlation.
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