I needed to disable self sign-ups because I’ve been getting too many spam-type accounts. Thanks.
Omega 3 supplementation: to be avoided at all cost
Quote from John Fry on January 22, 2019, 11:24 amThanks, that was entertaining to hear and see Brian at his "most ripped". I'm going to screen capture his slides and audio tape his presentation for the archives. It's hard to send his lectures to friends. Most people can't seem to get past his personality.
I have his PEO Solution book which is a really good read. Quite a few "eye-openers". The product based on his recommendations, YES PEO, is well-liked at Amazon's comment section. He's been "chased" a bit by the authorities, but that just seems to make him more adamant. He does go back at least ten years (his YouTube channel) and he was warning about the dangers of fish oil back then and probably earlier. I did a deep-dive on him and the subject he presents, just prior to discovering Grant's work. We were taking some YES PEO capsules, but not consistently or at therapeutic levels.
It is interesting how this overlaps the dangers of the Retinoids, and no doubt the other side of the damaged-tissue coin, which is having sufficient and proper building-blocks to make new cell membranes for the cells that are themselves making/repairing the membranes of higher-order structures in the body. It's kind of fractal.
Some of the content of the video of Dr. Matheson's clinical experience with the oils, which is like Part 2 of this one, (same conference) is almost unbelievable, but plausible. It's worth a two-month experiment with the oils at higher intake levels.
Since his product is somewhat expensive, I replicated it last year, pretty closely anyway, through buying the refrigerated nutritional oils separately; the ones made by Flora in Canada and then tried approximating Brian's ratios.
Buying UDO's 3-6-9 from Flora is also pretty close I think to what Brian has developed. Udo Erasmus wrote Fats That Heal, Fats That Kill a long time ago and he covered some of this material. I'm tempted to read that again and compare to knowledge gained since he wrote it. There is some debate, that is there would be if you could get the folks on the same platform, about the appropriate LA-to-ALA ratio (Omega 6-to-Omega 3).
(did an edit above - reversed the LA-to-ALA terminology in the first draft)
Patricia and Ed Kane have written an excellent history, with the conclusion that LA-to-ALA should be 4-to-1 based on a study in Israel from the early 90's. They give credit to the Flax/Cottage Cheese promoter from Germany, Johanna Budwig, a famous biochemist, but also show how she got it wrong. Wikipedia dismisses Budwig for her anti-cancer claims and only alludes to the importance of her fight against the hydrogenation industry and their adulteration of oils (1950's timeframe), which at the time was literally heroic as I understand it. Here's a snip from Wiki. Note her focus on a "low oxygen environment", just as Brian Peskin is pointing at in the video. I like how Brian talked about "cellular respiration" being like a mitochondrial blast-furnace. That particular membrane might be the most important one in existence.
While working as a researcher at the German Federal Health Office she noted many cancer drugs being evaluated in the 1950s contained sulphydryl groups. Budwig believed sulphydryl compounds were important to cellular metabolism and cellular respiration.[1] Budwig researched the theory that a low oxygen environment would develop in the absence of sulphydryl groups and/or fatty acid partners that would encourage the proliferation of cancerous cells.[1] With H.P. Kaufmann she developed paper chromatography techniques to identify and quantify fatty acids.[1] Budwig used these techniques to compare the fatty acid profiles of sick and healthy individuals. This made her one of the first scientists to consider the health implications of fat consumption, according to Mannion et al. in a 2010 paper in the journal Nutrients.[1]
Brian does reference Patricia Kane (I think it was once in his book), but doesn't give much credit as I recall. Anyway, here's the pdf from the BodyBio Bulletin. http://becknatmed.com/doc/BodyBioBulletin-4to1Oil.pdf
Ed and Patricia Kane's product BodyBio Balance Oil is found at Amazon. It only has Sunflower and Flax oils, whereas Brian's includes Pumpkin seed and Evening Primrose in addition to those two (maybe one other as well).
UDO's 3-6-9 has the following ingredients (don't know the ratios) - Omega-3 ALA (alpha-linolenic acid), Omega-6 LA (linoleic acid), GLA (gamma-linolenic acid), Omega-9 OA (oleic acid). Organic flax seed oil, organic sunflower seed oil, organic sesame seed oil, organic coconut oil, organic evening primrose seed oil, organic rice bran oil, organic soy lecithin, organic oat bran oil, mixed tocopherols (non-GMO).
Thanks again for linking the video. I think it's really important stuff.
Thanks again for an interesting post John. I did follow the budwig protocol back in october as I find the theory behind interesting. Quark and best quality flax oil. The quark fxcked me up badly, unsure if it was the quark only or if the oil contributed (phytoestrogens) but it made my endometriosis "explode". I wonder if they pasteurized the quark in Budwig's days..?
I had completely forgotten about udo's oil, it was very popular 20 years ago with fitness competitors back home during their competition diet for keeping skin smooth and soft.
Udo has the right ingredients but the wrong ratio ( 2 to 1 omega 3 to 6) according to Peskin.
i thought I'd purchase a Kindle copy of my Peskin book and post the info you want. The book is, The Hidden Story of Cancer. It doesn't appear to be available on Kindle. I suspect that it'd be available by interlibrary loan. Surely I wasn't foolish enough to discard my book! It now sells for a ridiculously high price these days!
Quote from DWL on January 23, 2019, 4:00 ami thought I'd purchase a Kindle copy of my Peskin book and post the info you want. The book is, The Hidden Story of Cancer. It doesn't appear to be available on Kindle. I suspect that it'd be available by interlibrary loan. Surely I wasn't foolish enough to discard my book! It now sells for a ridiculously high price these days!
Just noticed the same thing for the PEO SOLUTION book. My copy says $27.50 on the back cover. Amazon is quoting $42.50
I read their AI can fool around with the numbers based on "observing" one's habits and interests. Don't know, but it is odd to see that kind of mark-up.
I’m encountering the same problems I had when I first read PEO SOLUTION. Tons of really great information, delivered in a unique style, but then glaring WTF?’s. For example, on page 195 and 196 he has one chart labeled Ratio of Tissue Composition with 5 tissue types on the left and columns titled Percentage of Total Body Weight, Omega 6 PEO, Omega 3 PEO.
For Brain/Nervous System the ratio is 100 to 1. For Skin it’s 1,000 to 1 (with a note that skin has virtually NO omega 3). Organs and other Tissues at 4 to 1. Adipose tissue at 22 to 1. Muscle tissue at 6.5 to 1
Then he segues to a chart showing the predominance of Omega 6 in plasma lipids (with zero reference to where the numbers come from). This time Omega 6 and Omega 3 are on the left-hand column, with 4 Plasma Percentages across the top – Unesterified, Triglycerides, Phospholipids, Cholesterol Esters. Then a ratio for each column at the bottom ranging from 8.5 to 1 - 17.5 to 1 - 115 to 1 - 100 to 1
Then he does the same kind of thing he’s noted for in his lectures – he caroms off into something else that is off the subject he was developing – only to segue back with an odd statement. I’ll add a couple of paragraphs directly below that last chart.
“Since Omega-6 is the only PEO used in cooking, then if nothing is done to offset its adulteration, all organs, tissues, cells (100 trillion cells), and cellular mitochondria have impaired membranes. With 100 trillion cell membranes nonfunctional, would you expect problems? YES”.
(subliminal for his product there, but I digress) (that had zero to do with the theme he was working on - i.e. the proper ratio)
“Claims will be made that the average American consumes twelve to twenty times more Parent omega-6 than Parent omega-3. I have two responses. First, we need an 11:1 ratio, as the above clearly shows. The majority of Parent omega-6 is highly adulterated – at least 50% is not fully functional. Second, to reach a 20:1 ratio is highly improbable because animal-based protein includes Parent omega-3 in its cellular structure, and most people do consume some seafood each week”.
It’s like listening to a Jack Kruse lecture, where the firing of his synapses reminds one of a disco-ball dance hall. Granted, the whole book doesn’t read like that, and there’s a great deal of important info conveyed, but still, how many non-sequiturs are allowed in clear communication?
And I don’t get the math at all. How can he possibly come up with his odd ratio from those figures above? Not to mention the source of those numbers.
“First, we need an 11:1 ratio”. I’d be really interested to see the math on that.
And then, why is the product he’s involved with (yes, at an arm’s length; after some state-level hounding) much less than that? I don’t want to quote exactly what it is, since I was just flipping through the book when I came across my notes in the margin on that discrepancy above, and I can’t recall what his ratio actually is. 2.x - to - 1? Guest above says 2 - to - 1 Sounds right to me.
I think anyone seriously concerned about their lipid status should invest in a RBC Lipid Panel performed at the Kennedy Krieger Lab at Johns Hopkins and interpreted by Ed and Patricia Kane. The case studies at the end of the paper I linked are quite dramatic and the protocols are based on that lipid panel. I may do one just to report back on how messed up mine might still be from doing every diet and oil experiment under the sun over 30 years. It’s been on my do-list for a year now.
Fortunately, a lot of my intake was a version of the Budwig Protocol, only instead of blending Flax into Cottage Cheese (been there, done that) I used Hemp Oil instead, off and on for quite a few years. I even remember when it had a bit of THC left in it and a few of us wondered when the authorities would clamp down. Hemp oil is at a 3.8-to-1 ratio and is mentioned favorably by both the Kane’s and Udo Erasmus.
Getting this raw-material ratio part right is critical, especially for those of us who have already damaged our tissues with the Retinoids and would like our replacement cells to be as good as they can be.
To his credit, Brian does mention Patricia Kane (which also means he’s well aware of the Kane's 4-to-1 ratio, published since the mid-1990’s) when on page 162 under the heading – Carbohydrates Contribute to Cellular EFA (PEO) Deficiency And Insulin Resistance, Making Diabetes Even Worse! -he writes:
“For years I thought that, in addition to overdosing on carbohydrates, diabetics must be deficient in Parent omega-6 (EFAs) in the cell membranes. This would impair insulin effectiveness and cause insulin resistance. We have a worldwide diabetes epidemic and must do everything possible to stop its proliferation. My suspicion was justified, and I thank Patricia Kane, PhD, for confirming its metabolic pathway – release of Lp-PLA(2), which is increased in diabetics, making them more insulin resistant”.
I don’t have the bandwidth to verify just how much chutzpah is embedded in that paragraph, but from what I can intuitively sense, it’s partially a egotistic kind of back-handed compliment. And I still like the guy. He’s a pit-bull and we need that kind of passion, but we need to keep our discernment at a high level on this stuff, especially when products are being sold. I’d like to tour the plant that manufactures his capsules. Same for Patricia Kane’s BodyBio Balance Oil. I was an engineer and GMP, ISO, FDA audits, TQM and internals were part of my CV for 25 years. The thing that gives me more confidence with the Kane’s (product and narrative) is that they start patients with the base requirement of O-6 and O-3; before determining the needs for the other lipids and derivatives. And the high-level of their Phosphatidyl Choline product's status on a global basis. They’re in an elite group there. Thanks for reading.
P.S. - now that I think about it I'll probably just go back to mixing 80:20 with the two Flora refrigerated oils again (Sunflower:Flax) for a few months and then do the Kane's RBC lipid panel for the overview on paper. I'll let y'all know how it goes.
Quote from somuch4food on January 22, 2019, 1:58 pmInteresting paper analysing the differences between freshly pressed sunflower oil and refined.
It shows no alterations in fatty acid profile: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486537/
I'm thinking that oil bought from stores are Ok, but products made from those oils are rancids.
Ed Kane covers the need for cold-pressed processing under a blanket of nitrogen and immediate refrigeration in dark-colored bottles. He says light is 1000 times more damaging to the oils than exposure to air. It's on page 11 under Seed Oils.
http://becknatmed.com/doc/BodyBioBulletin-4to1Oil.pdf
I read the paper, thanks for that.
I'm thinking the product has a low ratio to be more marketable to mainstream. Omega 3s are seen as good and 6s as bad (since we already consume so much in processed foods), so selling a product with a 10:1 or 20:1 wouldn't be as profitable.
I don't think we need to worry too much about the exact ratio, just get more 6s than 3s from quality oils. Do you really think that life would have survived if it relied on exact ratios of anything?
I'm also not sure that the chemical treatment really alters the PEO profile of oils. I'm thinking it has more to do with the products made with those oils being exposed to light/air during production and handling.
Quote from somuch4food on January 23, 2019, 10:51 amI'm thinking the product has a low ratio to be more marketable to mainstream. Omega 3s are seen as good and 6s as bad (since we already consume so much in processed foods), so selling a product with a 10:1 or 20:1 wouldn't be as profitable.
I don't think we need to worry too much about the exact ratio, just get more 6s than 3s from quality oils. Do you really think that life would have survived if it relied on exact ratios of anything?
I'm also not sure that the chemical treatment really alters the PEO profile of oils. I'm thinking it has more to do with the products made with those oils being exposed to light/air during production and handling.
I hear ya, it's a bit of a conundrum, especially the survival thing. It's like we're so far from our ancestors way of life that now we're relying on a different kind of understanding, one that's not traditional, or local, for the most part. On the marketability idea, I'd bet Brian would never fess up to that. We should watch for one of his lectures in our area and ask him about it. As for chemical treatment? That was quite an extensive flow-chart in the paper, and Brian reproduces the same in his book. Guess it's partly about process-control, but there may be other variables they're overlooking. I don't know enough about lipid chemistry to understand what kind of damage to the lipids might be occurring, ones that they're not able to discern via chromatography or spectroscopy or whatever they're using. Kind of like missing Retinoic Acid in the early animal experiments. Reading Vit A papers and reviews at PubMed has led me to think some of this stuff can be conjured-up, which makes it difficult to sort the chaff from the wheat.
Quote from Liz on January 22, 2019, 10:12 pmQuote from John Fry on January 22, 2019, 11:24 amThanks, that was entertaining to hear and see Brian at his "most ripped". I'm going to screen capture his slides and audio tape his presentation for the archives. It's hard to send his lectures to friends. Most people can't seem to get past his personality.
I have his PEO Solution book which is a really good read. Quite a few "eye-openers". The product based on his recommendations, YES PEO, is well-liked at Amazon's comment section. He's been "chased" a bit by the authorities, but that just seems to make him more adamant. He does go back at least ten years (his YouTube channel) and he was warning about the dangers of fish oil back then and probably earlier. I did a deep-dive on him and the subject he presents, just prior to discovering Grant's work. We were taking some YES PEO capsules, but not consistently or at therapeutic levels.
It is interesting how this overlaps the dangers of the Retinoids, and no doubt the other side of the damaged-tissue coin, which is having sufficient and proper building-blocks to make new cell membranes for the cells that are themselves making/repairing the membranes of higher-order structures in the body. It's kind of fractal.
Some of the content of the video of Dr. Matheson's clinical experience with the oils, which is like Part 2 of this one, (same conference) is almost unbelievable, but plausible. It's worth a two-month experiment with the oils at higher intake levels.
Since his product is somewhat expensive, I replicated it last year, pretty closely anyway, through buying the refrigerated nutritional oils separately; the ones made by Flora in Canada and then tried approximating Brian's ratios.
Buying UDO's 3-6-9 from Flora is also pretty close I think to what Brian has developed. Udo Erasmus wrote Fats That Heal, Fats That Kill a long time ago and he covered some of this material. I'm tempted to read that again and compare to knowledge gained since he wrote it. There is some debate, that is there would be if you could get the folks on the same platform, about the appropriate LA-to-ALA ratio (Omega 6-to-Omega 3).
(did an edit above - reversed the LA-to-ALA terminology in the first draft)
Patricia and Ed Kane have written an excellent history, with the conclusion that LA-to-ALA should be 4-to-1 based on a study in Israel from the early 90's. They give credit to the Flax/Cottage Cheese promoter from Germany, Johanna Budwig, a famous biochemist, but also show how she got it wrong. Wikipedia dismisses Budwig for her anti-cancer claims and only alludes to the importance of her fight against the hydrogenation industry and their adulteration of oils (1950's timeframe), which at the time was literally heroic as I understand it. Here's a snip from Wiki. Note her focus on a "low oxygen environment", just as Brian Peskin is pointing at in the video. I like how Brian talked about "cellular respiration" being like a mitochondrial blast-furnace. That particular membrane might be the most important one in existence.
While working as a researcher at the German Federal Health Office she noted many cancer drugs being evaluated in the 1950s contained sulphydryl groups. Budwig believed sulphydryl compounds were important to cellular metabolism and cellular respiration.[1] Budwig researched the theory that a low oxygen environment would develop in the absence of sulphydryl groups and/or fatty acid partners that would encourage the proliferation of cancerous cells.[1] With H.P. Kaufmann she developed paper chromatography techniques to identify and quantify fatty acids.[1] Budwig used these techniques to compare the fatty acid profiles of sick and healthy individuals. This made her one of the first scientists to consider the health implications of fat consumption, according to Mannion et al. in a 2010 paper in the journal Nutrients.[1]
Brian does reference Patricia Kane (I think it was once in his book), but doesn't give much credit as I recall. Anyway, here's the pdf from the BodyBio Bulletin. http://becknatmed.com/doc/BodyBioBulletin-4to1Oil.pdf
Ed and Patricia Kane's product BodyBio Balance Oil is found at Amazon. It only has Sunflower and Flax oils, whereas Brian's includes Pumpkin seed and Evening Primrose in addition to those two (maybe one other as well).
UDO's 3-6-9 has the following ingredients (don't know the ratios) - Omega-3 ALA (alpha-linolenic acid), Omega-6 LA (linoleic acid), GLA (gamma-linolenic acid), Omega-9 OA (oleic acid). Organic flax seed oil, organic sunflower seed oil, organic sesame seed oil, organic coconut oil, organic evening primrose seed oil, organic rice bran oil, organic soy lecithin, organic oat bran oil, mixed tocopherols (non-GMO).
Thanks again for linking the video. I think it's really important stuff.
Thanks again for an interesting post John. I did follow the budwig protocol back in october as I find the theory behind interesting. Quark and best quality flax oil. The quark fxcked me up badly, unsure if it was the quark only or if the oil contributed (phytoestrogens) but it made my endometriosis "explode". I wonder if they pasteurized the quark in Budwig's days..?
I had completely forgotten about udo's oil, it was very popular 20 years ago with fitness competitors back home during their competition diet for keeping skin smooth and soft.
Sorry to hear that Liz. I had mixed-reviews about 25 years ago when the book came out and again 10 years later. Nothing like endometriosis going off the charts, but random things that were hard to pin down. Don't you wish these outdated books would come with an addendum? I haven't thought to add a comment at Amazon, but it makes sense. Short and sweet - refer readers to the better science and put in a plug for Grant's amazing work!!
Thanks for your comments, it's cool to share this stuff and learn from others on the front lines. I've got Grant's details printed on business cards and pass them out here and there. I'm seeing so many challenged kids wherever I go these days, but it's hard to walk up to their parents and say - "Hi, you might want to read this guys website and books." Wherever it makes sense I take the chance that I won't piss somebody off. Usually folks are OK and might even ask for details, but normally I don't hear back from anyone, no matter how close of friends or acquainted we are. But, it's still planting seeds, and I don't think most people throw business cards away. So it's there when they go, "what was that I heard about Vitamin A"?
I'm gonna experiment by removing most processed foods made in factories that contain oils (think long shelf life) and replacing with homemade goods or store bought foods made fresh on location.
I posted in another thread that I thought too much sugar was not making me feel good. I'm thinking it might have more to do with those sugary foods being made with fats that go rancid.